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Global Flow Cytometry Market - Product Image

Global Flow Cytometry Market

  • ID: 2142431
  • May 2014
  • Region: Global
  • 158 Pages
  • TriMark Publications

FEATURED COMPANIES

  • Abcam
  • BD Biosciences
  • Clarient (GE Healthcare)
  • Luminex
  • Promega Corporation
  • Spherotech
  • MORE

Flow cytometry is a laboratory analytical technique that can rapidly measure multiple parameters of individual cells or particles as they pass through a beam of light, typically a laser. The global flow cytometry market remains one of the fastest-growing segments of life sciences and clinical diagnostics markets. In the current life sciences research, pharmaceutical drug discovery and development, and clinical diagnostics markets, flow cytometry offers some of the brightest promise for growth and innovation.

The purpose of this report is to provide a detailed analysis of the global flow cytometry market, including size, growth, technology platforms, applications, new instrumentation, industry trends and the internal structure of the sector. The study covers highly attractive growth areas such as stem cell research, biomarkers and companion diagnostics, CD4 testing, high throughput screening and immunology and vaccine development.

It also analyzes almost all of the companies known to be marketing, manufacturing or developing flow cytometry products in the U.S. and worldwide. Additionally, this review provides detailed tables, charts and figures with past and projected sales data by geographic region for North America, Europe, Asia-Pacific and the emerging BRIC (Brazil, Russia, India and China) markets.

FEATURED COMPANIES

  • Abcam
  • BD Biosciences
  • Clarient (GE Healthcare)
  • Luminex
  • Promega Corporation
  • Spherotech
  • MORE

1. Overview
1.1 Statement of Report
1.2 About This Report
1.3 Scope of the Report
1.4 Methodology
1.5 Executive Summary
1.5.1 The Global Picture
1.5.2 Two Major Companies Dominate the Market
1.5.3 Reagents and Consumables Are the Fastest Growing Product Group
1.5.4 The HIV/AIDS Epidemic Has Created a Market for Point-of-Care Flow Cytometry
1.5.5 Flow Cytometry Will Advance Research and Development of New Cellular Therapies, Biologics
and Vaccines

2. Background and Development

3. Market Overview
3.1 Technology and Products
3.2 Market Environment
3.2.1 Global Economic Uncertainty
3.2.2 Lower Healthcare Utilization
3.2.3 Reduced Government Funding for Life Science Research
3.2.4 Consolidation of the Pharmaceutical Industry
3.2.5 Global Aid to Resource Limited Countries

4. Global Flow Cytometry Market 2013-2018
4.1 Global Flow Cytometry Market Size
4.2 Market Drivers
4.3 Market Restrictors
4.4 Flow Cytometry Market by User
4.4.1 Overview
4.4.2 Academic and Government Research Laboratories
4.4.3 Pharmaceutical and Biotechnology Companies
4.4.4 Hospital and Reference Clinical Laboratories
4.4.5 Niche Laboratories

5. Flow Cytometry Projected Revenue by Product. 2013-2018
5.1 Instruments and Service
5.2 Reagents and Consumables
5.3 Software

6. Market Analysis by Region
6.1 Market Size by Region
6.2 Developed Markets
6.2.1 North America
6.2.2 Western Europe
6.2.3 Asia-Pacific
6.3 Emerging Countries
6.3.1 Emerging Countries Projected Flow Cytometry Market
6.3.2 China
6.3.3 India
6.3.4 Brazil
6.3.5 Russia
6.4 Resource Limited Countries

7. Technology
7.1 Principle of Flow Cytometry
7.2 Fluidics
7.3 Optics
7.4 Electronics
7.5 Data Analysis
7.6 Cell Sorting
7.7 Labeling and Detection
7.8 Multiplex Bead Assays
7.9 Imaging Flow Cytometry

8. Applications
8.1 Research Applications
8.1.1 Detection of Cell Signaling Pathways in Single Cells
8.1.2 Cell Proliferation
8.1.3 Cell Viability
8.1.4 Apoptosis
8.1.5 Cell Cycle, DNA Content, Gene Expression
8.1.6 Multiplex Bead Assays
8.1.7 Stem Cell Research
8.1.8 Immunology Research and Vaccine Development
8.2 Clinical Diagnostics
8.2.1 Monitoring T-Cell Markers
8.2.2 Immunophenotyping of Leukemias and Lymphomas
8.2.3 Detection of Minimum Residual Disease
8.2.4 Anti-Neutrophil Antibody Detection in Auto-Immune and Immunodeficiency Disease
8.2.5 Platelet Associated Immunoglobulin Assays
8.2.6 Reticulocyte Count
8.2.7 HLA Crossmatching and Cell Analysis for Stem Cell and Organ Transplantation
8.2.8 Paroxysmal Nocturnal Hemoglobinuria
8.3 Pharmaceutical Applications
8.3.1 Biomarkers and Companion Diagnostics
8.3.2 Drug Discovery and High Throughput Screening
8.3.3 Toxicology
8.3.4 GMP Manufacture of Cellular Therapeutics
8.4 Global Health
8.4.1 Parasitic Diseases and Tropical Medicine
8.4.2 HIV/AIDS, Malaria and Tuberculosis
8.5 Niche Applications
8.5.1 Marine Biology
8.5.2 Plant Biology, Agriculture and Veterinary Medicine
8.5.3 Microbiology
8.5.4 Clinical Microbiology
8.5.5 Industrial Microbiology
8.5.6 Monitor Fermentation Processes
8.5.7 Monitor Water Quality
8.5.8 Screening Raw Materials and Finished Product

9. Flow Cytometry Instruments
9.1 High Performance Multicolor Analyzers
9.2 Midsize Flow Cytometers
9.3 Compact Flow Cytometers
9.4 Cell Sorters
9.5 Flow Cytometry Imaging Systems
9.6 High Throughput and Automated Systems
9.7 Multiplex Systems
9.8 Considerations When Purchasing a Flow Cytometry Instrument
9.9 Pricing

10. Flow Cytometry Reagents
10.1 Leading Suppliers of Reagents and Kits
10.2 Reagent Selection

11. Software and Bioinformatics

12. Competitive Landscape
12.1 Competitors and Market Share
12.2 Key Players
12.2.1 BD Biosciences
12.2.2 Beckman Coulter
12.2.3 Life Technologies
12.2.4 Luminex Corporation
12.2.5 EMD Millipore (Division of Merck KGaA)
12.2.6 Partec GmbH
12.2.7 Miltenyi Biotec
12.2.8 Affymetrix eBioscience

13. Industry Analysis
13.1 Trends
13.1.1 More Lasers, More Fluorescent Dyes, More Data
13.1.2 Moving Flow Cytometry Out of Core Laboratories
13.1.3 Higher Throughput
13.1.4 Clinical Scale Cell Sorting
13.1.5 Point-of-Care Flow Cytometry
13.2 Recent Industry Developments, 2011-2013

14. Innovation and New Technology
14.1 Cell-Analyzing Bio Chips for Point-of-Care Testing.
14.2 Microchip Based Disposable Cell Sorting Technology
14.3 Microfluidic Cell Sorter with Integrated Piezoelectric Actuator
14.4 On-Chip Sorting Using Acoustically Enhanced Magnetophoresis
14.5 NanoCytometry
14.6 Micro-Fabricated Fluorescence-Activated Cell Sorter
14.7 Flow Cytometry and a Cell Phone
14.8 Disposable Devices for CD4 T-Cell Enumeration
14.9 Non-Invasive Technique for Cytometric Analysis of Whole Blood
14.10 Innovative Startup Companies
14.10.1 Nanostring Technologies, Inc.
14.10.2 NanoCellect Biomedical, Inc.
14.10.3 Lamprogen

15. Gaps and Challenges
15.1 Software
15.2 Point-of-Care Flow Cytometry

16. Opportunities
16.1 Integrating Complementary Technologies
16.2 Automated Compound Screening
16.3 Specialized Flow Cytometers
16.4 Veterinary Testing
16.5 Marine Biology Systems
16.6 Plant Biology

17. Strategic Recommendations
17.1 Competing in the Flow Cytometry Market
17.2 International Operations Risks
17.3 Dependence on Government Funding and Healthcare Reform
17.4 Reimbursement for Clinical Diagnostics

18. The Point-of-Care Flow Cytometry Market
18.1 Introduction
18.2 Clinical Significance of the CD4 Test
18.3 Users
18.4 The Market Situation
18.5 The Regional Picture
18.5.1 Sub-Saharan Africa
18.5.2 India
18.5.3 Russia, Eastern Europe, Central Asia
18.5.4 China
18.5.5 Brazil
18.6 Market Projections 2013-2018
18.7 Competitive Landscape
18.8 Gaps and Challenges
18.8.1 Gaps
18.8.2 Challenges
18.9 Point-of-Care Flow Cytometry Innovation and New Technology
18.9.1 Immunochromatography
18.9.2 Cell Stacking/Sedimentation
18.9.3 Affinity Chromatography and Lysate Impedance Spectroscopy
18.9.4 Fluorescence Assay Illumination
18.9.5 Microchip Imaging Cytometry
18.9.6 Flow Cytometry and a Cell Phone
18.10 Point-of-Care Flow Cytometry Recent Industry Developments

19. Company Profiles
19.1 Abcam
19.2 Affymetrix eBioscience
19.3 Alere, Inc.
19.4 ALPCO Diagnostics
19.5 Apogee Flow Systems
19.6 Bangs Laboratories
19.7 Bay Bioscience
19.8 BD Biosciences
19.9 Beckman Coulter (Danaher)
19.10 Biocytex (Stago Group)
19.11 Bio-Rad Laboratories
19.12 BioVision
19.13 Cell Signaling Technology
19.14 Cira Discovery Sciences
19.15 Clarient (GE Healthcare)
19.16 Cytobank, Inc.
19.17 CytonomeST
19.18 Dako A/S
19.19 DVS Sciences, Inc.
19.20 IntelliCyt Corporation
19.21 Life Technologies
19.22 Luminex
19.23 EMD Millipore (Division of Merck KGaA Germany)
19.24 MBio Diagnostics
19.25 Miltenyi Biotec
19.26 Mindray
19.27 MiraiBio Group (Part of Hitachi Solutions America)
19.28 Nihon Kohden
19.29 Partec GmbH
19.30 PointCare Technologies
19.31 Promega Corporation
19.32 Propel Labs
19.33 R & D Systems (Techne Corporation)
19.34 Santa Cruz Biotechnology
19.35 Sigma-Aldrich
19.36 Soft Flow Hungary, Ltd.
19.37 Sony Biotechnology, Inc.
19.38 SouthernBiotech
19.39 Spherotech
19.40 Stratedigm
19.41 Sysmex
19.42 TaKaRa Bio
19.43 Thermo Fisher
19.44 Tree Star
19.45 TTP LabTech
19.46 Union Biometrica
19.48 U.S. Biological
19.49 Verity Software House

20. Acronyms Used in This Report

INDEX OF FIGURES

Figure 4.1: Flow Cytometry Market by User, 2013
Figure 5.1: Projected Market Growth by Flow Cytometry Product, 2013-2018
Figure 5.2: Flow Cytometry Market Distribution by Products, 2013
Figure 5.3: Flow Cytometry Market Distribution by Products, 2018
Figure 6.1: Global Flow Cytometry Market by Region, 2013
Figure 6.2: Global Flow Cytometry Market by Region, 2018
Figure 6.3: Five-Year Projected Flow Cytometry Market by Region, 2014-2018
Figure 6.4: Flow Cytometry Projected Growth Rate by Region, CAGR 2013-2018
Figure 6.5: Western Europe Flow Cytometry Market by Country, 2013
Figure 6.6: Emerging Countries Flow Cytometry Projected Market by Country, 2013-2018
Figure 6.7: Emerging Countries Flow Cytometry Market Share by Country, 2013
Figure 6.8: Emerging Countries Five-Year Growth Rate, CAGR 2013-2018
Figure 7.1: Schematic of a Flow Cell
Figure 7.2: Schematic of a Flow Cytometer Optical Layout
Figure 7.3: Example of a Dot Plot of Lysed Whole Blood
Figure 7.4: Fluorescence Intensity Histogram
Figure 7.4: Principle of Multiplex Bead Assay
Figure 12.1: Flow Cytometry Competitors’ Market Share, 2013
Figure 18.1: Global Distribution of HIV/AIDS Infected Persons Receiving Antiretroviral Therapy in Low-Middle Income Countries, 2012
Figure 18.2: Market Projection for POC Flow Cytometry in Middle to Low Income Countries, 2013-2018
Figure 18.3: Competitors’ Shares, Flow Cytometry and POC Instruments/Reagents/Consumables, 2013

INDEX OF TABLES

Table 2.1: Flow Cytometry Timeline
Table 3.1: Differences between Hematology Analyzers and Flow Cytometers
Table 3.2: Flow Cytometry Market Environment
Table 4.1: Flow Cytometry Projected Market Revenue, 2013-2018
Table 4.2: Flow Cytometry Market Drivers and Restrictors
Table 5.1: Flow Cytometry Projected Revenue by Product, 2013-2018
Table 5.2: Projected Market Growth by Flow Cytometry Product, 2013-2018
Table 6.1: Projected Flow Cytometry Market by Region, 2013-2018
Table 6.2: Flow Cytometry Projected Growth Rate by Region, CAGR 2013-2018
Table 6.3: North America Flow Cytometry Market Projected by Product, 2013-2018
Table 6.4: NIH Historical Spending, 2008-2012
Table 6.5: Flow Cytometry Systems in NIH Flow Cytometry Core Facilities
Table 6.6: CROs Specializing in Flow Cytometry Services
Table 6.7: Western Europe Flow Cytometry Market Projected by Product, 2013-2018
Table 6.8: Western Europe Flow Cytometry Market Projected by Country, 2013-2018
Table 6.9: Asia-Pacific Flow Cytometry Projected Market by Product, 2013-2018
Table 6.10: Emerging Countries Flow Cytometry Projected Market by Country, 2013-2018
Table 6.11: Emerging Countries Five-Year Growth Rate by Country, CAGR 2013-2018
Table 6.12: Emerging Countries Flow Cytometry Projected Market by Product, 2013-2018
Table 6.13: Resource Limited Countries Flow Cytometry Projected Market, 2013-2018
Table 7.1: Common Fluorophores Used in Flow Cytometry
Table 8.1: Cell Types, Proteins and Microbes Detected by Flow Cytometry
Table 8.2: Flow Cytometry Applications in Stem Cell Research
Table 8.3: Flow Cytometry Clinical Diagnostic Applications
Table 8.4: NIH Definition of Biomarkers
Table 8.5: Advantages of Flow Cytometry for High Throughput Screening
Table 8.6: Flow Cytometry Applications for Toxicology
Table 8.7: Neglected Tropical Diseases
Table 8.8: Flow Cytometers Products for Niche Applications
Table 8.9: Microorganisms Detected by Flow Cytometry
Table 9.1: Features: High Performance Analyzers
Table 9.2: Features: Midsize Analyzers for Research and Clinical IVD Applications
Table 9.3: Features: Midsize Analyzers for Research Applications
Table 9.4: Features: Compact Flow Cytometers
Table 9.5: Features: Cell Sorters
Table 9.6: Key Features of Multiplex Bead Systems
Table 9.7: Considerations When Selecting a Flow Cytometer
Table 12.1: Suppliers of Flow Cytometry Instruments, Reagents and Software
Table 12.2: North American Companies Participating in the Flow Cytometry Market
Table 12.3: Western European Companies Participating in the Flow Cytometry Market
Table 12.4: Asian Companies Participating in the Flow Cytometry Market
Table 12.5: BD Biosciences Selection of Flow Cytometry Instruments
Table 12.6: BD Biosciences Flow Cytometry Branded Reagents, Buffers and Solutions
Table 12.7: Beckman Coulter Flow Cytometry Instruments
Table 12.8: Beckman Coulter Branded Flow Cytometry Reagents
Table 12.9: Life Technologies Branded Flow Cytometry Reagents
Table 12.10: Luminex Instruments for Multiple Assay Analysis
Table 12.11: Luminex Branded Multiplex Assays and Reagents
Table 12.12: EMD Millipore Flow Cytometers
Table 12.13: EMD Millipore Brand Flow Cytometry Kits and Reagents
Table 12.14: Partec Flow Cytometry Instruments
Table 12.15: Partec Flow Cytometry Systems for Remote Testing
Table 12.16: Partec Reagents and Kits
Table 12.17: Miltenyi Biotec Branded Cell Separation and Flow Cytometry Products
Table 12.18: Affymetrix eBioscience Branded Reagents
Table 18.1: WHO Recommendations for the Use of Antiretroviral Drugs
Table 18.2: Global Distribution of HIV/AIDS Infected Persons Receiving Antiretroviral Therapy in Low-Middle Income Countries, 2012
Table 18.3: Top 12 Countries by Number of HIV/AIDS Infected Persons, 2012
Table 18.4: Market Projection for POC CD4 Systems in Middle to Low Income Countries, 2013-2018
Table 18.5: Point-of-Care Flow Cytometry Market Drivers and Restrictors
Table 18.6: CD4 Testing Platforms for Low to Middle Income Countries
Table 18.7: Optimal Features of a Point-of-Care CD4 Test System
Table 20.1: List of Acronyms Used in this Report

- Abcam
- Affymetrix eBioscience
- Alere, Inc.
- ALPCO Diagnostics
- Apogee Flow Systems
- Bangs Laboratories
- Bay Bioscience
- BD Biosciences
- Beckman Coulter (Danaher)
- Biocytex (Stago Group)
- Bio-Rad Laboratories
- BioVision
- Cell Signaling Technology
- Cira Discovery Sciences
- Clarient (GE Healthcare)
- Cytobank, Inc.
- CytonomeST
- Dako A/S
- DVS Sciences, Inc.
- IntelliCyt Corporation
- Life Technologies
- Luminex
- EMD Millipore (Division of Merck KGaA Germany)
- MBio Diagnostics
- Miltenyi Biotec
- Mindray
- MiraiBio Group (Part of Hitachi Solutions America)
- Nihon Kohden
- Partec GmbH
- PointCare Technologies
- Promega Corporation
- Propel Labs
- R & D Systems (Techne Corporation)
- Santa Cruz Biotechnology
- Sigma-Aldrich
- Soft Flow Hungary, Ltd.
- Sony Biotechnology, Inc.
- SouthernBiotech
- Spherotech
- Stratedigm
- Sysmex
- TaKaRa Bio
- Thermo Fisher
- Tree Star
- TTP LabTech
- Union Biometrica
- U.S. Biological
- Verity Software House

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