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Companion Diagnostic Collaboration and Licensing Deals 2010-2026

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    Report

  • 300 Pages
  • May 2026
  • Region: Global
  • CurrentPartnering
  • ID: 2300209

The definitive benchmark for companion diagnostic dealmaking

Companion diagnostic partnering is driven by the integration of diagnostics with therapeutic development, with deal structures reflecting co-development strategies, regulatory alignment, and precision medicine approaches.

This report provides a comprehensive and structured analysis of 560+ companion diagnostic collaboration and licensing deals, delivering a clear and evidence-based view of how partnerships are designed, negotiated, and executed across the market.

Establish a clear view of market standards

The report enables a precise understanding of how companion diagnostic deals are structured in practice, allowing you to:

  • Benchmark comparable transactions with confidence
  • Detailed analysis of upfronts, milestones, and royalty structures across relevant deals
  • Define realistic market parameters
  • Clear insight into how deal terms vary by technology type, therapeutic alignment, and partner profile
  • Support valuation and structuring decisions with evidence
  • Ground internal discussions in real transaction data rather than assumptions
  • Understand how leading companies approach dealmaking
  • Visibility into partner behaviour and recurring deal structures across a precision medicine-driven and co-development-focused landscape

Designed for real-world BD and strategy use

The report is widely used to:

  • Structure and benchmark diagnostic-therapeutic partnerships
  • Prepare for negotiations with well-defined market context
  • Evaluate co-development and licensing opportunities
  • Support internal strategy with robust, defensible data

What’s included?

  • 560+ companion diagnostic collaboration and licensing deals
  • Financial terms, including upfronts, milestones, and royalties where disclosed
  • Fully searchable deal directory (by company, technology, and therapeutic alignment)
  • Direct access to SEC-filed agreements and source documents
  • Analysis of deal trends, key transactions, and active dealmakers
  • A trusted, evidence-based reference for companion diagnostic dealmaking
Combining comprehensive deal coverage with contract-level insight, this report provides a trusted, evidence-based reference for how companion diagnostic partnerships are structured, negotiated, and valued.

Table of Contents

Executive SummaryChapter 1 - Introduction
Chapter 2 - Trends in companion diagnostic dealmaking
2.1. Introduction
2.2. Companion diagnostic deals over the years
2.3. Most active companion diagnostic dealmakers
2.4. Companion diagnostic deals by deal type
2.5. Companion diagnostic deals by therapy area
2.6. Companion diagnostic deals by industry sector
2.7. Deal terms for companion diagnostic deals
2.7.1 Companion diagnostic deals headline values
2.7.2 Companion diagnostic deal upfront payments
2.7.3 Companion diagnostic deal milestone payments
2.7.4 Companion diagnostic royalty rates
Chapter 3 - Leading companion diagnostic deals
3.1. Introduction
3.2. Top companion diagnostic deals by value
Chapter 4 - Most active companion diagnostic dealmakers
4.1. Introduction
4.2. Most active companion diagnostic dealmakers
4.3. Most active companion diagnostic deals company profiles
Chapter 5 - Companion diagnostic contracts dealmaking directory
5.1. Introduction
5.2. Companion diagnostic contracts dealmaking directory
Chapter 6 - Companion diagnostic dealmaking by technology type
Deal directory
  • Deal directory - Companion diagnostic deals by company A-Z
  • Deal directory - Companion diagnostic deals by deal type
  • Deal directory - Companion diagnostic deals by therapy area
  • Deal type definitions
List of Figures
Figure 1: Companion diagnostic deals since 2016
Figure 2: Active companion diagnostic dealmaking activity since 2016
Figure 3: Companion diagnostic deals by deal type since 2016
Figure 4: Companion diagnostic deals by therapy area since 2016
Figure 5: Companion diagnostic deals by industry sector since 2016
Figure 6: Companion diagnostic deals with a headline value
Figure 7: Companion diagnostic deals with an upfront value
Figure 8: Companion diagnostic deals with a milestone value
Figure 9: Companion diagnostic deals with a royalty rate value
Figure 10: Top companion diagnostic deals by value since 2016
Figure 11: Most active companion diagnostic dealmakerssince 2016
Figure 12: Companion diagnostic deals by technology type since 2016

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • 2cureX
  • 20/20 GeneSystems
  • A2 Biotherapeutics
  • Abbisko Therapeutics
  • Abbott Laboratories
  • Abbott Molecular
  • Abbvie
  • Abcam
  • AccuGenomics
  • Achaogen
  • Acrivon Therapeutics
  • ADC Therapeutics
  • Adial Pharmaceuticals
  • Advanced Biological Laboratories
  • Advanced Cell Diagnostics
  • Advanced Nuclear Medicine Ingredients
  • Advaxis
  • Aelan Cell Technologies
  • AEterna Zentaris
  • Affymetrix
  • Agilent Technologies
  • Agios Pharmaceuticals
  • Akili Interactive Labs
  • Akoya Biosciences
  • Albert Einstein College of Medicine
  • Algeta
  • Allarity Therapeutics
  • Allergan
  • Almac Diagnostics
  • Almac Group
  • Alphageneron Pharmaceuticals
  • AltheaDX
  • Amarantus BioSciences
  • Ambit Biosciences
  • Amgen
  • Amoy Diagnostics
  • AmpliPhi Biosciences
  • Analytics Engines
  • AnchorDx
  • Angle
  • AnHeart Therapeutics
  • Apogenix
  • Apollomics
  • ArcherDX
  • Ariad Pharmaceuticals
  • Arizona State University
  • ARK Diagnostics
  • Arno Therapeutics (inactive since 2017)
  • Array Biopharma
  • Arvinas
  • Ashvattha Therapeutics
  • AssureRx Health
  • Astellas Pharma
  • Astellas Pharma US
  • Astex Pharmaceuticals
  • AstraZeneca
  • Astrimmune
  • Asuragen
  • Atherotech
  • Atlas Antibodies
  • Aushon BioSystems
  • Australian Research Council
  • AVEO Oncology
  • Avila Therapeutics
  • Banner Sun Health Research Institute (BSHRI)
  • Bayer
  • Bayer Healthcare
  • BC Cancer Agency
  • Beckman Coulter
  • Becton Dickinson
  • BeiGene
  • Biocare Medical
  • Biocartis
  • Biocept
  • BioChain
  • Biodesix
  • Biogen
  • Biognosys
  • BioImagene
  • BioMarin Pharmaceutical
  • BioMarker Strategies
  • Biomedix
  • Biomerica
  • bioMerieux
  • Biomoda
  • BiomX
  • BioNTech
  • BioSkryb
  • Biovica
  • Bliss Biopharmaceutical
  • Blueprint Medicines
  • Boehringer Ingelheim
  • Bonnie J. Addario Lung Cancer Foundation
  • Boudicca Dx
  • Bpifrance
  • Brenus Pharma
  • Bristol-Myers Squibb
  • Bristol-Myers Squibb Pakistan
  • Burning Rock
  • Cadila Pharmaceuticals
  • California NanoSystems Institute (CNSI)
  • Calviri
  • Cambridge Biomedical
  • Canary Foundation
  • CANbridge Pharmaceuticals
  • Cancer Genetics
  • Cancer Research Technology
  • Cancer Research UK
  • Cancer Treatment Centers of America
  • Carena
  • Caris Life Sciences
  • Case Western Reserve University
  • Cedars-Sinai Medical Center
  • Celgene
  • Celladon
  • Celldex Therapeutics
  • Cellgen Diagnostics
  • Cell Signaling Technology
  • Centre for Imaging Technology Commercialization
  • Centre National de la Recherche Scientifique
  • Cephalon
  • Cepheid
  • Cernostics
  • CHDI Foundation
  • Chembio Diagnostics
  • Chronix Biomedical
  • Chugai Pharmaceutical
  • Ci-Co Healthcare
  • Clarient
  • Clavis Pharma
  • Clevexel Pharma
  • Clinical Reference Laboratory
  • Cloud Pharmaceuticals
  • Clovis Oncology
  • Columbia University
  • Columbia University Medical Center
  • CombiMatrix
  • CompanDX
  • Companion Dx Reference Lab
  • Companion Medical
  • Compendia Bioscience
  • ConcertAI
  • Corgenix Medical
  • Cornell University
  • Covance
  • CStone Pharmaceuticals
  • Cynvenio
  • Daiichi Sankyo
  • Dako
  • Dana-Farber Cancer Institute
  • David H. Murdock Research Institute
  • Day One Biopharmaceuticals
  • Debiopharm
  • Definiens
  • Denovo Biopharma
  • Department of Defense
  • DermTech
  • DiagnoCure
  • DiamiR
  • Diaxonhit
  • Dimerix Biosciences
  • DxS
  • Eisai
  • Eli Lilly
  • Emory University
  • Empire Genomics
  • Endocyte
  • Enlyten Medical Technologies
  • Enterome Bioscience
  • Enzo Biochem
  • Epic Sciences
  • Epigenomics
  • Epitomics
  • Epizyme
  • Erasmus University Medical Center
  • Erytech Pharma
  • Eureka Eurostars
  • Eurofins Scientific
  • European Union Regional Development Fund
  • Eutropics Pharmaceuticals
  • Evotec
  • ExonHit Therapeutics
  • Exosome Diagnostics
  • FEI
  • Ferring Pharmaceuticals
  • Fibrocell Science
  • FivepHusion
  • Five Prime Therapeutics
  • Flagship Biosciences
  • Flare Therapeutics
  • Foresight Diagnostics
  • Foundation Medicine
  • Fox Chase Cancer Center
  • Freenome
  • Fujirebio Diagnostics
  • Fusion Antibodies
  • FYR Diagnostics
  • Galena Biopharma
  • Galmed Pharmaceuticals
  • GE Healthcare
  • Geisinger Health System
  • Gemini Therapeutics
  • Genentech
  • Generex Biotechnology
  • Geneseeq
  • Genetic Technologies
  • Genetron Health
  • Genmab
  • Genome Diagnostics
  • GenomeDx
  • Genomeon
  • Genomic Health
  • Genomic Testing Cooperative
  • Genoptix
  • Genosity
  • Genzyme
  • German Cancer Research Center
  • German Federal Ministry of Education and Research
  • Gibson Oncology
  • GlaxoSmithKline Biologicals
  • Glythera
  • Golden Helix
  • Grail
  • GSK
  • Guardant Health
  • HalioDx
  • Halozyme Therapeutics
  • Health Discovery
  • Helix
  • Hengrui Therapeutics
  • Henlius Biotech
  • HiberCell
  • HMNC Brain Health
  • Hoffmann La Roche
  • Horizon
  • Horizon Discovery
  • Horizon Europe
  • Hospices Civils de Lyon
  • Hospital del Mar
  • HotSpot Therapeutics
  • HTG Molecular Diagnostics
  • Hybrigenics
  • I-mab
  • Icon
  • IDbyDNA
  • Idera Pharmaceuticals
  • Illumina
  • ImaginAb
  • Imanis Life Sciences
  • IMIDomics
  • ImmunID Technologies
  • ImmunoCellular Therapeutics
  • ImmunoGen
  • ImmusanT
  • IMPACT Therapeutics
  • IncellDx
  • Incyte
  • Informed Data Systems
  • Inform Genomics
  • Innovate UK
  • Inotrem
  • Inova Diagnostics
  • Inovio Pharmaceuticals
  • Inserm Transfert
  • Insight Genetics
  • InSphero
  • IntegraGen
  • Intezyne
  • Invivis Pharmaceuticals
  • InVivoScribe
  • Ionis Pharmaceuticals
  • Ipsen
  • Ipsogen
  • IRCCS
  • IRX Therapeutics
  • Janssen Biotech
  • Janssen Pharmaceutica NV
  • Janssen Research & Development
  • Jiangsu Hengrui Medicine
  • Johns Hopkins University
  • Johnson & Johnson Innovation
  • Kalgene Pharmaceuticals
  • Kanazawa University
  • Kartos Therapeutics
  • Karyopharm Therapeutics
  • KineMed
  • Kiyatec
  • Kreatech
  • Kronos Bio
  • KSB Diagnostics
  • Lab21
  • Laboratory Corporation of America
  • Lantern Pharma
  • Lawson Health Research Institute
  • Leap Therapeutics
  • Lehigh Valley Health Network
  • Leica Biosystems
  • Leica Microsystems
  • Les Laboratoires Servier
  • Life Technologies
  • Life Technologies Corporation
  • Locus Biosciences
  • London Genetics
  • Loxo Oncology
  • Luminex
  • Lumiphore
  • LUNGevity Foundation
  • Lunit
  • Luye Pharma Group
  • M42
  • Macquarie University
  • Macrogenics
  • MapKure
  • Massachusetts General Hospital
  • Massachusetts Institute of Technology
  • Max Planck Institute for Infection Biology
  • Mayo Clinic
  • MD Anderson Cancer Center
  • MDxHealth
  • Med BioGene
  • Medco Health Solutions
  • Medical Prognosis Institute
  • Medicover
  • MedImmune
  • Medivation
  • Medx
  • Memorial Sloan Kettering Cancer Center
  • Merck and Co
  • Merck KGaA
  • Merck Serono
  • Merrimack Pharmaceuticals
  • Merus
  • Metamark Genetics
  • MetaStat
  • Michael J Fox Foundation
  • Mikrogen
  • Millennium
  • Miragen Therapeutics
  • Mirati Therapeutics
  • MolecularMD
  • Montefiore Medical Center
  • Morphotek
  • Multimmune
  • Myriad Genetics
  • NanoString Technologies
  • Natera
  • National Cancer Institute
  • National Center for Drug Screening
  • National Heart
  • Lung and Blood Institute
  • National Institutes of Health
  • Navigate BioPharma Services
  • Nemucore Medical Innovations
  • Neogenix Oncology
  • Neogenomics
  • Networking Biomedical Research Centre in Liver and Digestive Diseases (CIBEREHD)
  • NeuroMetrix
  • Neuron23
  • Newcastle University
  • New Liberty Proteomics
  • New York University
  • Nicholas Conor Institute for Pediatric Cancer Research
  • Nihon Medi-Physics
  • NMI TT Pharmaservices
  • Nodality
  • North Carolina State University
  • NovAccess Global
  • Novartis
  • Novogene
  • Nuclea Biotechnologies
  • Nucleai
  • NuSirt
  • Nuvalent
  • OcellO
  • Offspring Biosciences
  • On-Q-ity
  • Oncoheroes Biosciences
  • Oncology Venture
  • OncoMed Pharmaceuticals
  • OncXerna Therapeutics
  • One Way Liver Genomics (OWL)
  • Ono Pharmaceutical
  • Ontario Cancer Biomarker Network
  • OPKO Health
  • Oridis Biomarkers
  • OrigiMed
  • Ortho-Clinical Diagnostics
  • OSE Immunotherapeutics
  • OSEO
  • OSI Pharmaceuticals
  • Oxford BioMedica
  • Oxford Gene Technology
  • Paradigm
  • PathAI
  • Patrys
  • Peking University Cancer Hospital
  • Penn State Hershey
  • PerkinElmer
  • Personal Genome Diagnostics
  • Personalis
  • Pfizer
  • Pharmacyclics
  • PharmaMar
  • Photocure ASA
  • Pierre Fabre
  • Pionyr Immunotherapeutics
  • Piramal Imaging
  • PMV Pharma
  • Precision for Medicine
  • Precision Therapeutics
  • Predicine
  • Primeradx
  • Profusa
  • Promega
  • Prometheus Biosciences
  • ProPath
  • Protagen
  • Proteomics International
  • Puma Biotechnology
  • Pure MHC
  • Q BioMed
  • QED Therapeutics
  • QIAGEN
  • Quest Diagnostics
  • Quintiles
  • R-Biopharm
  • R-Pharm
  • Race Oncology
  • Radius Health
  • RedHill Biopharma
  • Regulus Therapeutics
  • Relay Therapeutics
  • ResearchDx
  • Research Institute of the Hospital Universitari Vall d'Hebron
  • Resolution Bioscience
  • Respira Health
  • Revive Therapeutics
  • Roche
  • Roche Diagnostics
  • Roche Molecular Systems
  • Rush University Medical Center
  • Saladax Biomedical
  • Salix Pharmaceuticals
  • Samsung Medical Center
  • Sanofi
  • San Raffaele Scientific Institute
  • Scancell
  • Scandion Oncology
  • Seattle Genetics
  • Seegene
  • Sengenics
  • Sentinel Oncology
  • Seoul National University
  • Sequanta
  • Serametrix
  • Shenzhen Chipscreen Biosciences
  • Shuwen Biotech
  • Siemens Healthcare
  • Siemens Healthcare Diagnostics
  • Singapore Radiopharmaceuticals
  • Singulex
  • Sirius Genomics
  • Skysong Innovations
  • Small Business Innovation Research
  • Smart Personalized Medicine
  • Source Bioscience
  • Spectrum Pharmaceuticals
  • Splicos
  • Spruce Biosciences
  • SRL
  • St. Jude Children's Research Hospital
  • Stanford University
  • Strata Oncology
  • STRATIFYER Molecular Pathology
  • Sumitomo Dainippon Pharma
  • Sunnybrook Health Sciences Centre
  • SuperNova Diagnostics
  • Syapse
  • Syndax Pharmaceuticals
  • Synthon
  • Sysmex
  • Sysmex Inostics
  • T-Cure Bioscience
  • Takeda Pharmaceutical
  • Tasly Pharmaceuticals
  • TcLand Expression
  • Technology Strategy Board (UK)
  • Technology Transfer Accelerator
  • Telix Pharmaceuticals
  • Tempus
  • Tesaro
  • The Parker Institute For Cancer Immunotherapy
  • Theradiag
  • Thermo Fisher Scientific
  • Tocagen
  • Tokai Pharmaceuticals
  • Tolero Pharmaceuticals
  • Total Brain
  • TP Therapeutics
  • Tracer Biotechnologies
  • TRACON Pharmaceuticals
  • Transcenta
  • Transgene
  • Transgenomic
  • Translational Drug Development
  • TScan Therapeutics
  • uBiome
  • UCB
  • Undisclosed Company
  • Unilabs
  • University College London
  • University of Arkansas
  • University of Bonn
  • University of California
  • San Diego
  • University of California Los Angeles
  • University of Central Florida Research Foundation
  • University of Colorado Denver
  • University of Kansas
  • University of Minnesota
  • University of Newcastle
  • University of North Texas Health Science Center
  • University of Pennsylvania
  • University of Pennsylvania School of Veterinary Medicine
  • University of Pittsburgh Cancer Institute
  • University of Tokyo
  • University of Washington
  • USBiomarkers
  • ValiRx
  • Van Andel Institute
  • Vector Oncology
  • Vela Diagnostics
  • Ventana Medical Systems
  • Verastem
  • Veridex
  • VeriSIM Life
  • Vertex Pharmaceuticals
  • VieCure
  • Viewpoint Molecular Targeting
  • ViiV Healthcare
  • ViroMed
  • Virovek
  • Vyriad
  • Wake Forest University School of Medicine
  • WAVE Life Sciences
  • Whitehead Institute
  • WuXi NextCODE Genomics
  • XDx
  • Xencor
  • Xenon Pharmaceuticals
  • Yale University
  • ZAI Laboratory
  • Zinfandel Pharmaceuticals
  • Zora Biosciences

Methodology

  • The publisher reports provide insight into the trends and terms of partnering deals in the global life sciences sector.
  • The publisher reports are updated every six months to ensure the user has access to the latest announcements and trends in the topic focus of the report.
  • The publisher analysts review the deal data to provide an overview and analysis of deal trends, including example deals and terms.
  • The publisher reports source deal data from our proprietary deals and alliances database. The database is updated daily by our analysts with new deals as they are announced globally by the company’s party to the deal.
  • The data in the deals and alliances database is obtained from secondary sources such as publicly available industry sources including press releases, company presentations, investor presentations, company SEC filings, other company filings, company websites, conference presentations. Sources are identified to allow for user verification.

The publisher provides comprehensive coverage of the following partnering or deal types:

  • Asset purchase
  • Assignment
  • Co-development
  • Co-market
  • Co-promotion
  • Collaborative R&D
  • Contract service
  • CRADA
  • Cross-licensing
  • Development
  • Distribution
  • Equity purchase
  • Evaluation
  • Grant
  • Joint venture
  • Licensing
  • Loan
  • Manufacturing
  • Marketing
  • Option
  • Promotion
  • Research
  • Royalty financing
  • Settlement
  • Spin out
  • Sub license
  • Supply
  • Termination
  • Warrant

Every deal record is fully categorized and includes the following data, where available:

  • Industry sector
  • Therapy areas
  • Technology type
  • Deal components
  • Financial terms
  • Stage of development
  • Exclusivity
  • Asset type
  • Geographic focus
  • Excluded geography
  • Company press release
  • SEC filing data including contract document

All financial amounts are converted to US$ using the exchange rate available on the date of deal announcement, enabling direct comparison of deal terms across international territories.

 

 

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