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Oral Transmucosal Drug Delivery. Products, Players, Markets & Forecasts - Product Image

Oral Transmucosal Drug Delivery. Products, Players, Markets & Forecasts

  • Published: June 2012
  • Region: Global
  • Greystone Associates

In their search for alternative delivery methods that will enhance compliance and improve safety, drug developers and researchers are discovering that the permeability of mucous membranes provides a convenient route for the systemic delivery of new and existing therapeutic drugs. Transmucosal delivery offers the potential for once daily dosing of oral drugs and avoids the effects of first pass metabolism. On the provider side, the development of alternative methods of drug administration has improved the ability of physicians to manage specific problems. Practitioners now recognize the rapid onset, relative reliability, and the general lack of patient discomfort when drugs are administered by the transmucosal route. We expect this market to experience healthy growth through 2015 as buccal technology is applied to existing drugs and as transmucosal formulations become an important route of administration for an increasing number of new NCEs. Growth in this sector will also be driven by the pressure to extend market protection for numerous existing drugs with soon-to-expire patents.

Highlights:

-Analyzes and evaluates oral transmucosal drug delivery technology platforms READ MORE >

Executive Summary

Drug Delivery Market Dynamics

Evolution in Drug Development
Market and Demand Drivers
Shifting Patient Demographics
The Impact of Generics
Managed Care Initiatives
Competitive Landscape

Competing Transmucosal Delivery Technologies

Oral Sprays
Buccal Films and Tablets
Sublingual Films and Wafers

Commercial Transmucosal Formulation Platforms

Adversa
BEMA
Bioadhesive Delivery System
Corplex
FluidCrystal
Intravail
Lauriad
OraDisc
OraVescent
RapidMist
Transmucosal Film

Oral Transmucosal Drug Technology Factors

Absorption
Bioavailability
Adhesion
Pharmacokinetics

FDA-Approved Oral Transmucosal Products

Asenapine
Buprenorphine (3 products)
Ergotamine
Fentanyl (8 products)
Hydergine
Isosorbide dinitrate (2 products)
Miconazole
Nitroglycerin (3 Products)
Ondansetron
Testosterone
Zolpidem (3 products)
Zuplenz

Important Pipeline Product Candidates

Agomelatine
ALKS 5461
Buprenorphine
Buprehorphine
Buprenorphine
Cannabinoid
Desmopressin
Fentanyl
Fentanyl
Granisetron
Insulin
Ramelteon
Sufentanil
Sumatriptan
Zolpidem
Zolpidem

Market Assessments & Forecasts

Addiction
Anti-infectives
Cardiology
Diabetes
Immunology
Infectious Disease
Neurology
Oncology
Pain Management
Sexual Health
Vaccines

Market Factors

Formulations and Proprietary Platforms
Government Regulations
Patent Expiration and Rx-to-OTC Switching

Market Participant Profiles

Note: Product cover images may vary from those shown

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