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Competitor Analysis: Biosimilar and Biosuperior Therapeutic Antibodies Product Image

Competitor Analysis: Biosimilar and Biosuperior Therapeutic Antibodies

  • Published: March 2014
  • 386 Pages
  • La Merie Publishing

FEATURED COMPANIES

  • AbbVie
  • Avesthagen Pharma
  • Daiichi Sankyo (Ranbaxy)
  • iBio, Inc.
  • Molecular Templates
  • Protelica
  • MORE

The present Competitive Intelligence Report about Biosimilar and Biosuperior Therapeutic Antibodies 2014 provides a competitor evaluation in the field of recombinant monoclonal and polyclonal antibodies in the market, in the pipeline as next generation products and as biosimilar versions as of March 2014.

Marketed antibodies are attractive for companies to create next generation variants and biosimilar copies because they represent clinically and commercially validated products. New technologies such as Fc engineering, polyclonal mixtures, antibody drug conjugates or bispecific molecules as well as the expiration of patents stimulate the discovery and development of biosimilar and biosuperior/biobetter molecules.

Total sales of recombinant therapeutic monoclonal antibodies originating from companies located in regulated markets reached US$ 75.7 bln in the year 2013. Cumulated 2013 sales of branded therapeutic antibodies approaching patent expiry and, therefore, target of biosimilar substitution, reached US$ 58.6 bln.

The report lists specifically for each target the branded products with their 2013 sales and up-side indications in development, as well as follower, READ MORE >

Table of Contents

1. 2013 Sales of Recombinant Therapeutic Antibodies

Overview and Summary of Antibody Sales 2013
Cancer Antibody Sales 2013
Inflammatory and Autoimmune Antibody Sales 2013
Cardiohematometabolic Antibody Sales 2013
Ophthalmic Antibody Sales 2013
Antiviral Antiody Sales 2013

2. CD20 Antibodies - Rituximab Biosimilars and Biobetters/Biosuperiors

Marketed CD20 Antibodies & Sales
- Rituxan/MabThera Pipeline & Sales
- Arzerra Pipeline & Sales
- Gazyva Pipeline & Sales
- Bexxar & Zevalin Pipeline & Sales
Biosuperior CD20 Antibodies
Biosimilar CD20 Antibodies
- Rituxan/MabThera (rituximab) Biosimilars
- Arzerra (ofatumumab) Biosimilars

3. Her2 Antibodies - Trastuzumab Biosimilars and Biobetters/Biosuperiors

Marketed Her2 Antibodies
- Herceptin Sales & Pipeline
- Perjeta Sales & Pipeline
- Kadcyla Sales & Pipeline
Trastuzumab Biobetters/Biosuperiors
- Engineered Her2 Antibodies
- Bi- and Multispecific Her2 Antibodies
- Her2 Antibody-Drug Conjugates
- Her2 Imaging Antibodies
Trastuzumab Biosimilars

4. VEGF Antibodies – Bevacizumab and Ranibizumab Biosimilars and Biosuperiors

4a. Bevacizumab Biosimilars and Biosuperiors

Marketed VEGF Antibodies
- Avastin Sales & Pipeline
- Zaltrap Sales & Pipeline
“Next Generation Avastin” Pipeline
- Anti-VEGF Antibody Pipeline
- Anti-VEGF-Receptor Antibody Pipeline
- Bispecific Anti-VEGF Antibody Pipeline
Avastin Biosimilar Pipeline

4b. Ranibizumab Biosimilars and Biosuperiors

Marketed VEGF Antibody
- Lucentis Sales & Pipeline
- Eylea Sales & Pipeline
“Next Generation Lucentis” Pipeline
Lucentis Biosimilar Pipeline

5. EGF-R Antibodies –Biosimilars and Biosuperiors

Marketed EGF-R Antibodies
- Erbitux Sales & Pipeline
- Vectibix Sales & Pipeline
- Nimotuzumab Pipeline
EGF-R Antibody Biobetters/Biosuperiors
- Engineered EGF-R Antibodies
- Bi- and Multispecific EGF-R Antibodies
- EGF-R Antibody-Drug Conjugates
EGF-R Antibody Biosimilars
- Cetuximab Biosimilars
- Panitumumab Biosimilars

6. TNF Antibodies –Biosimilars and Biosuperiors

Marketed TNF Antibodies
- Humira Sales & Pipeline
- Remicade Sales & Pipeline
- Enbrel Sales & Pipeline
- Simponi Sales & Pipeline
- Cimzia Sales & Pipeline
Biosuperior / Biobetter TNF Antibodies
Biosimilar TNF Antibodies
- Humira Biosimilar Antibody Pipeline
- Remicade Biosimilar Antibody Pipeline
- Enbrel Biosimilar Antibody Pipeline
- Simponi Biosimilar Antibody Pipeline
- Cimzia Biosimilar Antibody Pipeline

7. IgE Antibodies: Xolair, Biosuperiors & Biosimilars
Marketed IgE Antibody Sales & Pipeline
Biosuperior IgE Antibodies
Biosimilar IgE Antibodies

8. Interleukin-6 Receptor (IL-6R) Antibodies: Actemra, Biosuperiors & Biosimilars
Marketed Il-6R Antibody Sales & Pipeline
Biosuperior IL-6(R) Antibodies
Biosimilar IL-6(R) Antibodies

9. GPIIb/IIIa Antibodies: ReoPro, Biosuperios & Biosimilars
Marketed GPIIb/IIIa Antibody Sales & Pipeline
Biosimilar GPIIb/IIIa Antibodies

10. CD52 Antibodies: Lemtrada, Biosuperios & Biosimilars
Marketed CD52 Antibody Sales & Pipeline
Biosimilar CD52 Antibodies

11. Apha4/beta1/7 Antibodies: Tysabri, Biosuperiors & Biosimilars
Marketed Alpha4/beta1/7 Antibody Sales & Pipeline
Biosimilar Alpha4/beta1/7 Antibodies

12. Complement C5 Antibodies: Soliris, Biosuperiors & Biosimilars
Marketed C5 Antibody Sales & Pipeline
Biosuperior C5 Antibodies
Biosimilar C5 Antibodies

13. Respiratory Syncytial Virus (RSV): Synagis, Biosuperiors & Biosimilars
RSV Antibody Sales & Pipeline
Biosuperior RSV Antibodies
Biosimilar RSV Antibodies

14. RANKL Antibodies: Prolia/XGEVA, Biosuperiors & Biosimilars
Marketed RANKL Antibody Sales & Pipeline
Biosuperior RANKL Antibodies

15. CD80/86 (B7-1/B7-2) Antibodies: Orencia; Nulojix, Biosuperiors & Biosimilars
CD80/86 Antibody Sales & Pipeline
Biosuperior CD80/86 Antibodies
Biosimilar CD80/86 Antibodies

16. Interleukin-12/-23 Antibodies: Stelara, Biosuperiors & Biosimilars
Marketed IL-12/-23 Antibody Sales & Pipeline
Biosimilar IL-12/-23 Antibodies

17. Corporate Biosimilar and Biosuperior Therapeutic Antibody Pipelines

- AbbVie
- Ablynx
- Actavis (Watson Pharmaceuticals)
- Actogenix
- ADC Therapeutics
- Affitech
- AIMM Therapeutics
- Alder Biopharmaceuticals
- Alexion Pharmaceuticals
- Allergan
- Allozyne
- Alopexx Oncology
- Alteogen
- Ambrx
- Amega Biotech
- Amgen
- Angiochem
- Apexigen
- Aprogen
- arGEN-X
- Aridis Pharmaceuticals
- Astellas Pharma
- AstraZeneca
- Avaxia Biologics
- Avesthagen Pharma
- Axxo
- Baliopharm
- Baxter
- Bayer HealthCare Pharmaceuticals
- Binex
- biOasis Technologies
- Biocad
- Biocon
- Biogen Idec
- Biosidus
- BioXpress
- Boehringer Ingelheim
- Bristol-Myers Squibb (BMS)
- Catalent Biologics
- Celgene
- Celltrion
- Centro de Imunologia Molecular AB (CIMAB)
- Cipla
- Circadian Technologies
- Clearside Biomedical
- Coherus Biosciences
- Covagen
- CSL
- Curaxys
- CytomX Therapeutics
- Daewoong Pharmaceutical Co
- Daiichi Sankyo (Ranbaxy)
- Delenex
- Dong-A Pharmaceutical
- Dr. Reddy’s
- Eddingpharm
- Effimune
- Eisai
- Eli Lilly
- Emergent BioSolutions
- Epirus Biopharmaceuticals
- Esperance Pharmaceuticals
- f-star
- Ferring Pharmaceuticals
- Fresenius Biotech (Neopharm)
- Fujifilm Kyowa Kirin Biologics
- Fusion Therapeutics
- Gansu Duyiwei Biological Pharmaceutical Co
- Gedeon Richter
- Genmab
- GlaxoSmithKline
- Glycotope
- Green Cross
- Hanwha Biologics
- Harvest Moon Pharmaceuticals
- Hospira
- Humabs Biomed
- IBC Generium
- iBio, Inc.
- Ildong Pharmaceutical Co
- ImmunoGen
- Immunomedics
- Innovent Biologics
- Intas Pharmaceuticals
- ISU Abxis
- Jiangsu Simcere Pharmaceutical Co
- Johnson & Johnson (J&J, Janssen)
- KAHR Medical
- Lentigen
- LG Life Sciences
- Libbs Farmaceutica
- MabXience
- MacroGenics
- Mapp Biopharmaceuticals
- Med Discovery
- Mentrik Biotech
- Merck
- Merck KGaA
- Merrimack Pharmaceuticals
- Mersana Therapeutics
- Merus
- Mitsubishi Tanabe Pharma
- Molecular Partners
- Molecular Templates
- Mycenax Biotech
- Mylan
- Nanogen Biopharmaceutical Co
- Natco Pharma
- Nichi-iko Pharmaceutical
- Nippon Kayaku
- Novartis (Alcon Research)
- NovImmune
- Novo Nordisk
- Oncobiologics
- Oncomed Pharmaceuticals
- Orygen Biotecnologia
- PanGenerika
- PanPharmaceuticals USA
- Paras Biopharmaceuticals
- Pfenex
- Pfizer
- PharmAbcine
- PharmaPraxis
- Pieris
- PlantFarm
- Probiomed
- Protalix Biotherapeutics
- Protelica
- R-Pharm
- Redwood Biosciences
- Regeneron Pharmaceuticals
- rEVO Biologics
- Roche
- RuiYi (Anaphore)
- Samsung Bioepis (JV of Samsung Biologics & Biogen Idec)
- Sandoz (Novartis)
- Sanofi
- Shanghai Biomabs Pharmaceutical
- Shanghai Celgen Bio-Pharmaceutical Co
- Shanghai CP Guojian Pharmaceutical Co., Ltd. (CPGJ)
- Shenyang Sunshine Pharmaceutical Co (3SBio)
- Sorrento Therapeutics
- Spectrum Pharmaceuticals
- Stada Arzneimittel
- Symphogen
- Synthon Biopharmaceuticals
- Takeda Pharmaceutical Co
- Targa Therapeutics
- TG Therapeutics
- Therapeutic Proteins International (TPI)
- Trimer Biotech
- TRION Pharma
- Tunitas Therapeutics
- UCB
- Vaccinex
- Valor Biotherapeutics (JV of ImmunGene & Caliber Biotherapeutics)
- Viropro
- WuXi AppTec
- Xencor
- Yuhan
- Zhejiang Huahai Pharmaceutical Co
- Zhejiang Medicine Co
- Zyngenia

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