- Language: English
- 441 Pages
- Published: September 2014
- Region: Global
Next Generation Sequencing (Genome/Exome sequencing/DNA sequencing) Global market - Forecast to 2020
- Published: February 2015
- Region: Global
- 220 Pages +
- IQ4I Research & Consultancy Pvt. Ltd
Next Generation Sequencing (NGS) enables rapid sequencing of large stretches of DNA base pairs spanning entire genomes capable of producing hundreds of gigabases of data in a single sequencing run. NGS is one of the fastest growing segments in genomics, triggering several ground breaking discoveries in genomic science. NGS technologies will therefore have a striking impact on cancer management, treatments of rare diseases and future developments of genetic therapies. The global next generation sequencing market is mainly categorized into pre-sequencing, NGS platforms and services, NGS data analysis, and storage and management.
Next generation sequencing market is one of the fastest growing segments in the genomics market with an estimated CAGR of around 17.0% in the next five years. The major factors such as rapid adoption of this technology by researchers and its usability as a substitute of microarray technology in addition to its higher throughput, increased accuracy, and affordable costs are driving the next generation sequencing market growth. However, factors such as reducing capital expenditure from academic institutions and huge dependability on grants funding from the government are hampering the next generation sequencing market growth. In addition, the analysis of large amount of data generated by sequencers, and data storage and management is posing a major challenge. The growth opportunities of this market include cloud computing, rising demand for pre-sequencing, developments in NGS fully integrated instruments and rising nanopore sequencing technology.
There is a huge opportunity for this technology in the field of drug discovery, personalized medicine, agricultural and animal research.
The North American region accounts for the largest share of the next generation sequencing market. The European and Asian markets are also expected to grow due to the favorable funding from the government to adopt this technology. The major factors contributing to this market growth include rising adoption by new customers, rising adoption of high-throughput sequencing platforms by government organizations such as Biotechnology and Biological Sciences Research Council (BBSRC) (U.K.) and NHGRI (National Human Genome Research Institute) (U.S.).
The key players dominating in the next generation sequencing market include Illumina Inc. (U.S.), Life Technologies Corporation (U.S.), Roche Holding AG. (Switzerland), Pacific Biosciences of California Inc. (U.S.), Ambry Genetics Corp. (U.S.), Axeq Technologies Inc. (U.S.), Beijing Genomics Institute (China), GeneDx (U.S.), Fluidigm Corp. (U.S.), Foundation Medicine Inc. (U.S.), Good Start Genetics Inc. (U.S.), Helicos BioSciences Corp. (U.S.), Knome Inc. (U.S.), NABsys Inc. (U.S.), Oxford Nanopore Technologies Ltd. (U.K.), Pathogenica Inc. (U.S.), and QIAGEN N.V. (The Netherlands). Among these Illumina accounted for the largest market share of more than 40%. The most widely used platforms for NGS sequencing are Roche/454 Life Technologies (Pyrosequencing), the Illumina/Solexa Genome Analyzer (Sequencing by synthesis) the Applied Biosystems SOLiD System (sequencing by ligation), the Helicos, Heliscope (single molecule sequencing) and Pacific Biosciences SMRT (single molecule real time sequencing). Whole genome sequencing, targeted re-sequencing, de novo sequencing, RNA-Seq, ChIP-Seq and methyl-Seq are the major applications that use NGS data analysis tools and services.
The report provides an in depth market analysis of the above mentioned segments across the following regions:
- North America
- Rest of the World (RoW)
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1 Executive summary
2.1 Key take aways
2.2 Report description
2.3 Markets covered
2.5 Research Methodology
2.5.1 Market Size estimation
2.5.2 Market crack down & data triangulation
2.5.3 Secondary Research Resources
3 Market Analysis
3.2 Market segmentation
3.3 Factors Influencing Market
3.3.1 Drivers and Opportunities
3.3.2 Restraints and Threats
3.3.4 Burning issues
3.4 Porter's five force analysis
3.5 Regulatory affairs
3.6 Market Share Analysis by Major players
4 Next Generation Sequencing market, by products
5 DNA Sequencing Market, By Technology
5.2 Targeted Resequencing
5.2.1 Targeted Resequencing by Regi on
5.3 Whole Exome Sequencing
5.3.1 Whole Exome Sequencing by Region
5.4 RNA Sequencing
5.4.1 RNA Sequencing by Regi on
5.5 Whole Genome Sequencing
5.5.1 Whole Genom e Sequencing by Region
5.6 chiP sequencing
5.6.1 chiP sequencing by Region
5.7 De novo sequencing
5.7.1 De novo sequencing by Region
5.8 Methyl Sequencing
5.8.1 Methyl Sequencing by Regi on
6 DNA Sequencing Market, By End Users/Laboratories
6.2 Academic Research
6.2.1 Academic Research by Regi on
6.3 Hospitals and Clinics
6.3.1 Hospitals and Cli nics by Region
6.4.1 Biotech/Pharm acy by Regi on
6.5.1 Others by Region
7 DNA Sequencing Market, By Application Areas
7.3 Drug discovery
7.4 Biomarker discovery
7.5 Personalized Medicine
7.6 Agriculture and Animal Research
8 Geographical Analysis
8.2 North America
8.5 Rest of the World
9 Company Developments
9.2 New Product Launch
9.4 Agreements, Partnerships, Collaborations & Contracts
9.5 Mergers & Acquisitions
10 Major Companies
10.1 Agilent Technologies, Inc.
10.2 Beijing Genome Institute
10.3 Biomatters, Ltd.
10.4 Genomatix Software Gmbh
10.5 Illumina Inc.
10.6 Life Technologies Corp.
10.7 Pacific Biosciences of California Inc.
10.8 Qiagen N.V
10.9 Roche Holding Ltd.
10.10 Strand Life Sciences Pvt. Ltd
- Agilent Technologies, Inc.
- Beijing Genome Institute
- Biomatters, Ltd.
- Genomatix Software Gmbh
- Illumina Inc.
- Life Technologies Corp.
- Pacific Biosciences of California Inc.
- QIAGEN N.V
- Roche Holding Ltd.
- Strand Life Sciences Pvt. Ltd.