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Global Biosimulation Technology Market (For Drug Discovery & Development) (2012 – 2017) - Product Image

Global Biosimulation Technology Market (For Drug Discovery & Development) (2012 – 2017)

  • Published: October 2012
  • Region: Global
  • 123 Pages
  • Markets and Markets

FEATURED COMPANIES

  • Accelyrs, Inc.
  • Certara
  • Compugen
  • Genedata Ag
  • Insilico Biotechnology Ag
  • Leadscope, Inc.
  • MORE

Biosimulation refers to computer aided simulation of biological processes and systems, an integral part of systems biology used in drug discovery and development. This report will analyze the potential of biosimulation in drug discovery and development. Biosimulation is used across the drug discovery and development program (such as target identification, target validation, lead discovery, lead optimization, preclinical and clinical test).

The global biosimulation market was valued at $432.0 million in 2011 and is expected to reach $1.2 billion by 2017, at a CAGR of 18.50%. Biosimulation in preclinical and clinical stages contributed maximum share (60%) to the global biosimulation market in 2011.

The major driving factor for this market is the cost and time spent on drug discovery and development programs and failure of drug candidates in the late development stages. Pharmaceutical companies around the globe spent around $68 billion in 2011 in drug discovery and development programs, many of the drug discovery and development programs fail in the late stages of the clinical trials, wasting all the years of efforts and money. There is a need for predictive technology which READ MORE >

1 Introduction

1.1 Key Take Aways

1.2 Report Description

1.3 Markets Covered

1.4 Stakeholders

1.5 Research Methodology

1.5.1 Market Size

1.5.2 Market Share

1.5.3 Key Data Points From Secondary Sources

1.5.4 Key Data Points From Primary Sources



2 Executive Summary



3 Market Overview

3.1 Introduction

3.2 Market Segmentation

3.3 Market Dynamics

3.3.1 Drivers

3.3.1.1 Need For New Tools In Drug Discovery Process

3.3.1.2 Increased Spending On Healthcare

3.3.1.3 Cost Attributed To The Traditional Drug Discovery Process

3.3.1.4 Failure Of Drug Candidates In The Late Development Stages

3.3.1.5 Improved Computational Power

3.3.1.6 Improved Modelling & Simulation Tools

3.3.2 Restraints

3.3.2.1 Unproven Predictive Methodology

3.3.2.2 Risk Of Potential Safe Drug Failing In Biosimulation

3.3.2.3 Lack Of Standardization

3.3.2.4 Limited Knowledge Of Biological Systems & Process

3.3.3 Challenges

3.3.3.1 Increasing Accuracy In Prediction

3.3.3.2 Increasing Collaboration/Partnership Among Vendors & Pharmaceutical Companies

3.3.3.3 Integration Of Other Technologies For Better Predictive Models

3.3.4 Trends

3.3.4.1 Drug Repositioning

3.3.4.2 In Patient Medication

3.3.5 Swot Analysis

3.3.5.1 Strengths

3.3.5.2 Weakness

3.3.5.3 Opportunities

3.3.5.4 Threats



4 Global Biosimulation Market, By Application

4.1 Segmentation Based On Applications

4.2 Application In Drug Discovery

4.2.1 Target Identification

4.2.1.1 Protein Structure Prediction

4.2.2 Target Validation

4.2.2.1 Molecular Modeling

4.2.3 Lead Identification/Discovery

4.2.3.1 De Novo Design

4.2.4 Lead Optimization

4.2.4.1 Qsar (Quantitative Structure–Activity Relationship) Models

4.3 Application In Drug Development

4.3.1 Pre-Clinical Testing

4.3.1.1 Adme/Tox Prediction

4.3.1.2 Pharmacokinetic/Pharmacodynamic (Pk/Pd) Models

4.3.2 Clinical Trials

4.3.2.1 Phase I Clinical Trial

4.3.2.2 Phase Ii Clinical Trial

4.3.2.3 Phase Iii Clinical Trial

4.3.3 In Patient Validation



5 Current Trends &Developments

5.1 Modeling And Simulations In Paediatrics Drug Development

5.2 Modelling & Simulations In Neglected Diseases Drug Development

5.2.1 Drug Repositioning

5.2.2 Grid Enabled Drug Discovery Model



6 Geographic Analysis

6.1 Introduction

6.2 North America

6.3 Europe

6.4 Asia

6.5 Rest Of The World

6.6 Trends In Asia



7 Competitive Landscape

7.1 Introduction

7.2 Porter’S Five Force Analysis

7.3 Mergers & Acquisitions

7.4 Partnerships, Agreements, Collaborations & Joint Ventures

7.5 New Product Launches

8 Company Profile

8.1 Accelyrs, Inc.

8.1.1 Overview

8.1.2 Financials

8.1.3 Products & Services

8.1.4 Strategy

8.1.5 Developments

8.2 Advanced Chemistry Development (Acd/Labs)

8.2.1 Overview

8.2.2 Products & Services

8.2.3 Strategy

8.2.4 Developments

8.3 Archimedes, Inc.

8.3.1 Overview

8.3.2 Products & Services

8.3.3 Developments

8.4 Certara

8.4.1 Overview

8.4.2 Products & Services

8.4.3 Strategy

8.4.4 Developments

8.5 Chemical Computing Group

8.5.1 Overview

8.5.2 Products & Services

8.5.3 Strategy

8.5.4 Developments

8.6 Compugen

8.6.1 Overview

8.6.2 Financials

8.6.3 Products & Services

8.6.4 Developments

8.7 Entelos, Inc.

8.7.1 Overview

8.7.2 Products & Services

8.7.3 Developments

8.8 Genedata Ag

8.8.1 Overview

8.8.2 Products & Services

8.8.3 Strategy

8.8.4 Developments

8.9 In Silico Biosciences, Inc.

8.9.1 Overview

8.9.2 Products & Services

8.10 Inhibox, Ltd

8.10.1 Overview

8.10.2 Products & Services

8.10.3 Developments

8.11 Insilico Biotechnology Ag

8.11.1 Overview

8.11.2 Products & Services

8.11.3 Developments

8.12 Leadinvent

8.12.1 Overview

8.12.2 Products & Services

8.13 Leadscope, Inc.

8.13.1 Overview

8.13.2 Products & Services

8.13.3 Strategy

8.14 Molecular Knowledge Systems, Inc.

8.14.1 Overview

8.14.2 Products & Services

8.14.3 Developments

8.15 Nimbus Discovery Llc

8.15.1 Overview

8.15.2 Products & Services

8.15.3 Developments

8.16 Open Eye Scientific Software, Inc.

8.16.1 Overview

8.16.2 Products & Services

8.16.3 Developments

8.17 Physiomics Plc

8.17.1 Overview

8.17.2 Financials

8.17.3 Products & Services

8.17.4 Strategy

8.17.5 Development

8.18 Rhenovia Pharma S.A.S

8.18.1 Overview

8.18.2 Products & Services

8.18.3 Strategy

8.18.4 Developments

8.19 Schrodinger

8.19.1 Overview

8.19.2 Financials

8.19.3 Products & Services

8.19.4 Strategy

8.19.5 Developments

8.20 Simulations Plus, Inc.

8.20.1 Overview

8.20.2 Financials

8.20.3 Products & Services

8.20.4 Strategy

8.20.5 Developments

8.21 Synergix Ltd

8.21.1 Overview

8.21.2 Products & Services

8.21.3 Developments





List Of Tables



Table 1 Cost & Time Involved In Drug Discovery Process

Table 2 Biosimulation Market Revenue, By Geography, 2012 – 2017 ($Million)

Table 3 Insilico Target Identification Market Revenue, By Geography, 2012 – 2017 ($Million)

Table 4 Insilico Target Validation Market Revenue, By Geography, 2012 – 2017 ($Million)

Table 5 Insilico Lead Discovery Market Revenue, By Geography, 2012 – 2017 ($Million)

Table 6 Insilico Lead Optimization Market Revenue, By Geography, 2012 – 2017 ($Million)

Table 7 Insilico Adme/Tox Prediction Market Revenue, By Geography, 2012 – 2017 ($Million)

Table 8 Insilico Pk/Pd Model Market Revenue, By Geography, 2012 – 2017 ($Million)

Table 9 Insilico In Clinical Trial, Market Revenue, By Geography, 2012 – 2017 ($Million)

Table 10 North America: Biosimulation Market Revenue, By Segments, 2012 – 2017 ($Million)

Table 11 Europe: Biosimulation Market Revenue, By Segments, 2012 – 2017 ($Million)

Table 12 Asia: Biosimulation Market Revenue, By Segments, 2012 – 2017 ($Million)

Table 13 Row: Biosimulation Market Revenue, By Segments, 2012 – 2017 ($Million)

Table 14 Mergers & Acquisitions, 2009 – 2012

Table 15 Partnerships, Agreements, Collaborations & Joint Ventures, 2009 – 2012

Table 16 New Product Launches, 2009 – 2012





List Of Figures



Figure 1 Market Revenue Forecast, 2012 – 2017

Figure 2 Bubble Chart: Region Wise Market Share & Growth Rate

Figure 3 Segmentation Of Biosimulation Market

Figure 4 Market Share Analysis Of Major Players

Figure 5 Application Of Biosimulation In Drug Discovery & Development Process

Figure 6 Market Share By Segments, 2011

Figure 7 Market Share By Application, 2011

Figure 8 Procedure Of Protein Structure Prediction

Figure 9 Insilico Target Identification Market Revenue, By Geography, 2012 – 2017 ($Million)

Figure 10 Market Share Of Protein Predicting Software & Servers, 2011

Figure 11 Insilico Target Validation Market Revenue, By Geography, 2012 – 2017 ($Million)

Figure 12 Market Share Of Molecular Modelling Software & Programmes, 2011

Figure 13 Insilico Lead Discovery Market Revenue, By Geography, 2012 – 2017 ($Million)

Figure 14 Market Share Of De Novo Design Software, 2011

Figure 15 Insilico Lead Optimization Market Revenue, By Geography, 2012 – 2017 ($Million)

Figure 16 Market Share Of Qsar Models, 2011

Figure 17 Analysis Of Main Reasons For Attrition In Drug Development

Figure 18 Insilico Adme/Tox Prediction Market Revenue, By Geography, 2012 – 2017 ($Million)

Figure 19 Adme-Tox Market Share Analysis, 2011

Figure 20 Pk/Pd Model Representation

Figure 21 Insilico Pk/Pd Model Market Revenue, By Geography, 2012 – 2017 ($Million)

Figure 22 Pk/Pd Market Share Analysis, 2011

Figure 23 Insilico In Clinical Trial, Market Revenue, By Geography, 2012 – 2017 ($Million)

Figure 24 Acceptance Level Of Modelling & Simulations In Drug Discovery & Development Process

Figure 25 Market Analysis Of Technologies Used In Drug Discovery & Development

Figure 26 Modelling And Simulation In Paediatrics Drug Development

Figure 27 M&S In Paediatric Drug Development

Figure 28 Regional Marker Life Cycle Analysis

Figure 29 Biosimulation Market Revenue Growth Trend, By Region, 2011& 2017

Figure 30 Biosimulation Market Growth Rate, By Region, 2012 – 2017

Figure 31 Biosimulation Market Revenue, By Region, 2011 – 2017

Figure 32 North America: Biosimulation Market Revenue, By Segments, 2012 – 2017 ($Million)

Figure 33 Europe: Biosimulation Market Revenue, By Segments, 2012 – 2017 ($Million)

Figure 34 Asia: Biosimulation Market Revenue, By Segments, 2012 – 2017 ($Million)

Figure 35 Row: Biosimulation Market Revenue, By Segments, 2012 – 2017 ($Million)

Figure 36 Key Growth Strategies, 2009 – 2012

Figure 37 Porter’S Five Force Analysis

- Accelyrs, Inc.

- Advanced Chemistry Development (Acd/Labs)

- Archimedes, Inc.

- Certara

- Chemical Computing Group

- Compugen

- Entelos, Inc.

- Genedata Ag

- In Silico Biosciences, Inc.

- Inhibox, Ltd

- Insilico Biotechnology Ag

- Leadinvent

- Leadscope, Inc.

- Molecular Knowledge Systems, Inc.

- Nimbus Discovery Llc

- Open Eye Scientific Software, Inc.

- Physiomics Plc

- Rhenovia Pharma S.A.S

- Schrodinger

- Simulations Plus, Inc.

- Synergix Ltd

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