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Nanotechnology in Drug Delivery - Global Strategic Business Report Product Image

Nanotechnology in Drug Delivery - Global Strategic Business Report

  • ID: 2769238
  • January 2014
  • Region: Global
  • 202 Pages
  • Global Industry Analysts, Inc

This report analyzes the worldwide markets for Nanotechnology in Drug Delivery in US$ Million. The Global Market is further analyzed by the following Drug Delivery Technologies: Nanocrystals, and Nanocarriers.

The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2018.

Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs.

The report profiles 60 companies including many key and niche players such as:

- Access Pharmaceuticals, Inc.
- Alkermes PLC
- Aquanova AG
- Camurus AB
- Capsulution Pharma AG
- Celgene, Inc.

NANOTECHNOLOGY IN DRUG DELIVERY

MCP-7808 A GLOBAL STRATEGIC BUSINESS REPORT
CONTENTS

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations
Disclaimers
Data Interpretation & Reporting Level
Quantitative Techniques & Analytics
Product Definitions and Scope of Study
Nanotechnology and Nanomedicine
Nanotechnology in Drug Delivery
Nanotechnology Drug Delivery Systems
Nanocrystals
Nanocarriers

II. EXECUTIVE SUMMARY
1. OUTLOOK
Nanotechnology - the Next Big Thing in Drug Development
Present Status and Opportunities that Lie Ahead
Current & Future Analysis
Major Market Drivers
Nanocrystals Outperform Nanocarriers
Liposomes - Leading the Way
Dendrimers Serve as a Base to Build Multifunctional Nanodevices

2. INDUSTRY OVERVIEW
Nanotechnology - An Introduction
Impact of Nanotechnology in a Nutshell
How Does Nanotechnology Help Drug Delivery?
Drug Delivery Technologies - A Fast Rising Market
Select Key Requirements for Development of Advanced Drug Delivery Systems
Drug Delivery - A Key Application of Nanotechnology in Medicine
Major Milestones in the Evolution of Nanotechnology- based Drug Delivery Materials
Table 1: Global Nanomedicine market by Application: Percentage Breakdown of the Market for Drug Delivery, Implants, In vivo Diagnostics and In vitro Diagnostics (includes corresponding Graph/Chart)
Nanotechnology Rescues Poor Water Soluble Drugs from Abandonment
Nanotechnology Promises to Play Enabling Role in Delivery of New Therapeutics
The Need for Targeted Delivery
The Difficulty in Clinical Use of Targeted Delivery
NEM Devices as Drug Delivery Vehicles
Nanotechnology - In Pursuit of Co-Delivery of Drugs
Nanoparticles in Minimizing or Averting Multi-Drug Resistance
Nanoscale Devices Enable Delivery of Multi-functional Therapeutics
Theranostics - A Potential Application of Nanotechnology-based Co-Delivery
Nanoemulsions Begin to Make a Mark
Growing Application of Nanoemulsions
A Review of Select Investigational Nanoemulsion Formulations

3. TRENDS & ISSUES
Tough Market Conditions Drive Interest in Nanotechnology-Based Drug Delivery
Table 2: Select Major Drugs Scheduled to Lose Patent Protection through 2013-2016: Annual Global Sales for Years 2010 & 2011
Table 3: Number of Drugs (NMEs and NBEs) Approved by US FDA: 2001-2012 (includes corresponding Graph/Chart)
Table 4: Number of Drugs (NMEs and NBEs) Approved by European Medicines Agency: 2010-2012 (includes corresponding Graph/Chart)
Unmet Needs to Surge Interest in Nanotechnology- based Drug Delivery
Narrowing Drug Pipelines and Threat from Generics Raise Interest in Nanotechnology
Size - A Critical Factor in Improving Targeting Capability
Shape of Drug Carriers More Important than Size - A New Revelation
Existing Nanotechnology Drugs are Simple
Creation of New Therapeutics - The Next Avenue for Nanotechnology
Consumer Pull to Benefit Nanotechnology Based Drugs
Oral Therapies to Revel from Advances in Nanotechnology
Increasing Funding for Nanotechnology Based Therapeutics Development
Table 5: Global Annual Government Funding for Nanotechnology for Years 2003-2012 (includes corresponding Graph/Chart)
Convergence of Enabling Technologies - A New Phase in Drug Delivery
Cloudy Future Threatens Advanced Drug Delivery Technologies with Premature Demise
Increasing Environmental and Health Concerns - A Critical Challenge to Technological Advancement
Limited Success and Scaling Up Issues Pose a Major Hurdle to Further Advancement
Financial and Economic Challenges Hurt Developmental Efforts
Higher Concentration of Research in Academia limits Commercialization
Collaborations Assume Importance
Nano Drug Delivery to Drive Tremendous Industry Activity Going Ahead
Challenges to Leveraging Technological Advancements for Boosting Drug Delivery Efficiency
Nanomedicine Regulation - the Approach and the Issues Associated
Regulations in Nanotechnology - Still Significant Room Exists for Improvement

4. NANOTECHNOLOGY-BASED DRUG DELIVERY APPLICATIONS
Modern Technological Advancements Take Forward Drug Delivery Systems
List of Select Nanomedicines Approved by FDA
Select Non-targeted Nanoparticles in Drug Delivery in Mid
and Late-Stage Clinical Trials
New Technology Enabled Depot Formulations
An Insight into Key Areas of Application
Cancer Therapy
Nanotechnology to Revolutionize Cancer Therapy
Nanoparticles Change Therapeutic Index of Chemotherapeutic Agents
List of Select Nanoparticle Drug Delivery Systems and Uses in Cancer Therapies
A Review of Select Nanotechnology-Based Delivery Systems in Anti-Cancer Therapies
Albumin - A Key Delivery Vehicle
Micellar Nanoparticle Formulation of Paclitaxel
Liposomal Formulation of Anti-Cancer Therapies
Dendrimers Finding Extending Use in Nanoparticle based Anti-Cancer Drug Delivery
Polymeric Micelles in Cancer Drug Delivery
Nanotechnology in Pulmonary Delivery of Drugs
Increasing Attention towards Pulmonary Delivery of Nanoparticle-Based Drugs
Liposomes - The Popular Choice for Drug Delivery through Lungs
Other Nanovehicles in Pulmonary Delivery
SLNs in Pulmonary Delivery of Drugs
Tuberculosis Treatment - A Major Application of Pulmonary Delivery
Nanotechnology in Infectious Disease Treatment
Nanotechnology Finds Increasing Role in Fighting Infectious Diseases
Liposomes
Liposomes - Leading the Way in Antimicrobial Nanotechnology-Based Drug Delivery
Overview of Select Liposome-Delivered Antimicrobial Products
Polymeric Nanoparticles
Solid Lipid Nanoparticles
Dendrimers
List of Select Nanotechnology-based Antimicrobial Drugs in Clinical Use
Nanotechnology Opening New Avenues in Antiretroviral Therapy
Demonstrated Activity of Select Nanotechnology- Delivered Antiretroviral Therapies
Nanotechnology in Delivery of CNS Therapeutics
The Blood-Brain Barrier and Effectiveness of Therapeutics
Nanoparticles Provide a Safer Means to Circumvent BBB
Nanotechnology in Delivery of Therapeutics for Ocular Conditions
New Forms of Drug Delivery to Treat Ocular Conditions
Efficient Drug Delivery through Micro-sized Implants
Pain Management
Timed-release Topical Formulation Offers Pain Relief from Arthritis and Acute Injuries
MyOmega 3 for Relief from Flares of Gouty Pain
MyOmega 3 Comes with Two Pain Relieving Products
Nano-Icepearls Particles Technology - The Driver of MyOmega 3
Polymeric Nanoparticles Promise Better Treatment for Childhood Leukemia
Nano-immunology - Still in Nascent Stages

5. PRODUCT OVERVIEW
Defining Nanotechnology and Nanomedicine
Nanotechnology in Drug Delivery
Applications of Nanoparticles in Drug Delivery
Nanotechnology-Based Drug Delivery Technologies by Segment
Nanocrystals
Nanocarriers
Nanostructures in Drug Delivery
Features of a Rational Nanocarrier
List of Select Nanomaterials Being Studied or Developed for Drug Delivery
Drug Delivery Technologies, Forms and Materials
Overview of Select Major Nanocarriers
Comparison of Key Attributes of Select Major Nanocarriers
Liposomes
List of Select Drugs/Compounds Demonstrated for Efficacious Liposome-based Delivery
Polymeric Nanoparticles
List of Select Drugs Demonstrated for Efficacious Polymeric Nanoparticle-based Delivery
Dendrimers
List of Select Drugs Demonstrated for Efficacious Dendrimer-based Delivery
Solid Lipid Nanoparticles (SLNs)
Nanotubes
List of Select Drugs Demonstrated for Efficacious Nanotube-based Delivery
Polymeric Micelles
Nanocapsules
Fullerenes
Nanostructure Synthesis
Top-Down Approach
Bottom-Up Approach
Requisites for Optimal Nanoparticle Design
Size and Surface Charge of the Nanoparticle
PEGylation and Ligand Functionalization

6. RECENT INDUSTRY ACTIVITY
Labtec Changes Name to tesa Labtec
Andain Announces Development of Drug Delivery Nano-Particles
Bind Therapeutics Teams-up with Pfizer
FDA Clears Abraxis’s Abraxane for First Line Pancreatic Cancer Treatment
pSivida Inks Agreement to Evaluate Tethadur Protein/Antibody Delivery Technology
Venus Medicine Research Centre to Invest in Nanotechnology Product Research
mPhase Files Patent for New Drug Delivery System Based on Smart Surface Technology
Midatech Generates Funding for Development of Chemotherapeutic Gold Nanoparticles
Galen Acquires DaunoXome® from Gilead Sciences
Exploit Technologies Releases New Delivery System for Worldwide Licensing, Partnering
Celator and Cephalon Extend Research Agreement
Morphotek Acquires Assets of Tumor-Targeting Peptide Platform from TransMolecular
Encap and Lena Join Forces for Developing Nano-Capsule Technology
Dolomite Unveils New Microfluidic System for Synthesis of Nanoparticle
Osaka Bioventure to Develop Anti-Inflammatory Transdermal Patch in US
Quantum Materials and Nanoaxis Form Technology Alliance
BioAlliance Gets European Patent for Its Transdrug Nanotechnology
Kadmon and Nano Terra Form Joint Venture for Nano-Level Drug Delivery
Yissum Announces Successful Pre-Clinical Results for Oral Delivery of Docetaxel Using Nanotechnology
Thailand and South Korea Sign MOU for Joint Nanotechnology Research
IBM and Institute of Bioengineering and Nanotechnology Utilize Semiconductor Nanotechnology to Treat Infectious Diseases
Camurus Enters into License Agreement with Novartis
Flamel Technologies Inks Agreement with GlaxoSmithKline
Eagle Pharmaceuticals Inks Development and License Agreement with Flamel Technologies
Alkermes and Elan Drug Technologies Ink Merger Agreement
AAIPharma and CritiTech Enter into Partnership
Midatech and Monosol Sign Expanded Collaboration Agreement
Celator Receives US Patent for CombiPlex® Technology Platform
Sosei Acquires Activus Pharma
Charlesson Obtains Funding for Development of Anti-Glaucoma Drug
Aphios Obtains US Patent for the Polymer Drug Delivery Nanotechnology Platform
Celator to Participate in NCI's Characterization Studies for Nanoparticle Prodrug Delivery System
Celgene Takes Over Abraxis BioScience

7. FOCUS ON SELECT PLAYERS
Access Pharmaceuticals, Inc. (US)
Alkermes PLC (Ireland)
Aquanova AG (Germany)
Camurus AB (Sweden)
Capsulution Pharma AG (Germany)
Celgene, Inc. (Canada)
Ceramisphere Pty Ltd. (Australia)
Crititech LLC (US)
EnColl Corporation (US)
Enzon Pharmaceuticals, Inc. (US)
Flamel Technologies SA (France)
Lena Nanoceutics Ltd. (UK)
NanoBio® Corporation (US)
NanoCarrier Co., Ltd. (Japan)
Nano Interface Technology, Inc. (US)
pSivida Corp. (US)

8. GLOBAL MARKET PERSPECTIVE
Table 6: World Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
Table 7: World 10-Year Perspective for Nanotechnology in Drug Delivery by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2009, 2013 & 2018 (includes corresponding Graph/Chart)
Table 8: World Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery by Technology - Nanocrystals and Nanocarriers Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
Table 9: World 10-Year Perspective for Nanotechnology in Drug Delivery by Technology - Percentage Breakdown of Dollar Sales for Nanocrystals and Nanocarriers Markets for Years 2009, 2013 & 2018 (includes corresponding Graph/Chart)

III. MARKET
1. THE UNITED STATES
A.Market Analysis
Current & Future Analysis
Market Overview
Select Key Statistics
Table 10: Number of Nanotechnology Submissions to CDER by Platform and Application (includes corresponding Graph/Chart)
Table 11: Nanotechnology Submissions to CDER by Platform: Percentage Breakdown of Number of Submissions for Liposomes, Nanoparticles, Nanocrystals, Micelles, SPIO and Others (includes corresponding Graph/Chart)
Table 12: Nanotechnology Submissions to CDER by Indication/Application: Percentage Breakdown of Number of Submissions for Oncology, Pain Management, Infectious Diseases, MRI, Immunosuppression and Others (includes corresponding Graph/Chart)
Table 13: Nanotechnology Submissions to CDER by Route of Administration: Breakdown of Number of Submissions for Intravascular, Inhalation, Oral, Topical and Other Injections (includes corresponding Graph/Chart)
Table 14: Liposomal Formulation-Based Submissions to CDER by Route of Administration: Breakdown of Number of Submissions for Intravascular, Inhalation, Oral and Other Injections (includes corresponding Graph/Chart)
Table 15: Nanoparticle Formulation-Based Submissions to CDER by Route of Administration: Breakdown of Number of Submissions for Intravascular, Oral, Inhalation, Topical and Other Injections (includes corresponding Graph/Chart)
FDA’s Regulatory Approach to Nanotechnology Products
Regulatory Evolution of Nanomedicine in the US
The Perils of Current Regulatory Status on Nanostructures
Few Challenges Faced by FDA
Competition
Overview of Select Key US Nanomedicine Companies Focused on Nano Drug Delivery
Strategic Corporate Developments
Select Players
B.Market Analytics
Table 16: US Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)

2. CANADA
A.Market Analysis
Current & Future Analysis
Key Player
B.Market Analytics
Table 17: Canadian Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)

3. JAPAN
A.Market Analysis
Current & Future Analysis
Nanomedicines in Japan - An Overview
List of Select Nanomedicines Approved in Japan
Regulations on Nanomedicine in Japan
Strategic Corporate Developments
Key Player
B.Market Analytics
Table 18: Japanese Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)

4. EUROPE
A.Market Analysis
Current & Future Analysis
The Rise of Nanotechnology Based Drug Delivery in Europe
EU Gears Up for Clarity on Nanomedicine Regulations
Harmonization of Regulations - A Key Goal for EMA
B.Market Analytics
Table 19: European Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery by Geographic Region
France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
Table 20: European 10-Year Perspective for Nanotechnology in Drug Delivery by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets for Years 2009, 2013 & 2018 (includes corresponding Graph/Chart)
4a. FRANCE
A.Market Analysis
Current & Future Analysis
Nanotechnology and Nanomedicine in France - An Overview
Overview of Select Major French Nanomedicine Companies Focused on Drug Delivery
Regulations on Nanomaterials
Strategic Corporate Developments
Key Player
B.Market Analytics
Table 21: French Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
4b. GERMANY
A.Market Analysis
Current & Future Analysis
Germany - A Regional Hub for Nanomedicine Research
Overview of Select Major German Nanomedicine Companies Focused on Nano Drug Delivery
Strategic Corporate Development
Key Players
B.Market Analytics
Table 22: German Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
4c. ITALY
Market Analysis
Table 23: Italian Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
4d. THE UNITED KINGDOM
A.Market Analysis
Current & Future Analysis
UK Bets on Advancing Nanotechnology
Strategic Corporate Developments
Key Player
B.Market Analytics
Table 24: UK Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
4e. SPAIN
Market Analysis
Table 25: Spanish Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
4f. RUSSIA
Market Analysis
Table 26: Russian Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
4g. REST OF EUROPE
A.Market Analysis
Current & Future Analysis
Strategic Corporate Developments
Key Players
B.Market Analytics
Table 27: Rest of Europe Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market
Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)

5. ASIA-PACIFIC
Market Analysis
Table 28: Asia-Pacific Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery by Geographic Region - China and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
Table 29: Asia-Pacific 10-Year Perspective for Nanotechnology in Drug Delivery by Geographic Region
Percentage Breakdown of Dollar Sales for China and Rest of Asia-Pacific Markets for Years 2009, 2013 & 2018 (includes corresponding Graph/Chart)
5a. CHINA
A.Market Analysis
Current & Future Analysis
New Findings Reinforce Role of Silica Nanoparticles in Drug Delivery and Diagnostics
Nanotechnology Patent Profile in China
Table 30: Number of Patents filed for Nanotechnology-based Drug Delivery in China by Country (includes corresponding Graph/Chart)
B.Market Analytics
Table 31: Chinese Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market - Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)
5b. REST OF ASIA-PACIFIC
A.Market Analysis
Current & Future Analysis
Indian Nanotechnology Market - An Overview
Nanotechnology to Spur Indian Pharmaceutical Industry
Major Players
Strategic Corporate Developments
Key Player
B.Market Analytics
Table 32: Rest of Asia-Pacific Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market
Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)

6. LATIN AMERICA
Market Analysis
Table 33: Latin American Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market
Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)

7. REST OF WORLD
A.Market Analysis
Current & Future Analysis
Strategic Corporate Development
B.Market Analytics
Table 34: Rest of World Recent Past, Current & Future Analysis for Nanotechnology in Drug Delivery Market
Analyzed with Annual Sales Figures in US$ Million for Years 2009 through 2018 (includes corresponding Graph/Chart)

IV. COMPETITIVE LANDSCAPE
Total Companies Profiled: 60 (including Divisions/Subsidiaries - 60)
The United States (28)
Canada (2)
Japan (3)
Europe (16) - France (4) - Germany (3) - The United Kingdom (5) - Rest of Europe (4) A
sia-Pacific (Excluding Japan) (10)
Middle East (1)

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