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Your Search for 'Immunogenicity to Biologics' returned 40 results - Page 1 of 2

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  • Next-Generation Protein and Peptide Therapeutics

    Scripp Business Insights, Aug 2011 , Pages: 192
    Next-Generation Protein and Peptide Therapeutics The utility of mAb therapeutics is balanced by many drawbacks: they are expensive to produce, have poor tissue penetration, can only be used to target ...
  • Conference: Cell Based Assays: Scientific Innovations & Market Analysis

    Appel Consulting Ltd, Jun 2013 , Days: 2
    Head Biologics Novartis 12:00 Cellular systems to address the efficacy, selectivity and mechanism of action of kinase inhibitors - Cell based system for assessing the activity and selectivity of ...
  • Biosimilars: Current Situation & Future Prospects, Worldwide

    Just Pharma Reports, Mar 2012 , Pages: 135
    problems related to use of biosimilars Immunogenicity potential of selected biologics Frequency of antibody formation; biosimilars and reference products Sandoz’ principles for science-based biosimilar ...
  • Biobetters: Major Players and Market Prospects (2nd edition)

    FirstWord Publishing, Sep 2011 , Pages: 48
    immunogenicity as a defensive shield - Prediction is a risky game - Clinical trials as the current gold-standard for immunogenicity testing - Biobetters – the route to market - The full approval pathway beckons ...
  • Biosimilars and Biobetters: Positioning for a New Market 2009

    Select Biosciences Ltd, Jul 2009 , Pages: 275
    companies to enter the biologics market, a segment which is uniquely driven by unmet needs, commands premium prices, and continues to outperform the global pharma market. This new and timely report analyzes ...
  • Anti-TNF Therapies in IBD: Opinion Leader Insight into Current & Future Treatment Practices

    Sociable Pharma, Apr 2011 , Pages: 130
    begun to reshape the treatment landscape for inflammatory bowel disease. There are now well-established treatment strategies for biologics in both Crohn's disease and ulcerative colitis but it will be the ...
  • Conference: 3rd Biosimilars Summit & Trade Exhibition - 2013 Innovations & Developments : A Decade at a Glance

    Appel Consulting Ltd, Jun 2013 , Days: 2
    3.7billion in 2015. With more than 30 branded biologics with sales of $51billion set to lose patent exclusivity. Between 2011 and 2015, it is forecast that “biosimilar monoclonal antibodies” and “second ...
  • Therapeutic antibody engineering: Current and future advances driving the strongest growth area in the pharmaceutical industry

    Woodhead Publishing Ltd, Sep 2012 , Pages: 640
    engineering. Introduction to biologics and monoclonal antibodies - Value proposition for therapeutic monoclonal antibodies and Fc fusion proteins - Antibody structure–function relationships - Fundamental ...
  • Novel Antibodies & Therapeutic Proteins: Technological Challenges & Future Prospects

    PharmaVision, Aug 2010 , Pages: 183
    remain to improve the cost-effective manufacture and production of biologics, and to enhance their delivery, pharmacokenetics and reduce immunogenicity. Despite these issues recent advances in mAbs and TPs ...
  • Biosimilars and Biobetters: Positioning for a New Market

    Biophoenix Limited, Jul 2009 , Pages: 275
    enter the biologics market, a segment which is uniquely driven by unmet needs, commands premium prices, and continues to outperform the global pharma market. This new and timely report analyzes the ...
  • Biosimilar Drugs in Europe: Threat or Opportunity to Innovation?

    FirstWord Publishing, Nov 2011 , Pages: 47
    International - Andrew Teuten, Senior Partner, Sagittarius IP Key Quotes “The size of the global biologics market creates a massive opportunity for biosimilar developers to come in and take some of that market ...
  • Biosimilars Update

    FirstWord Publishing, Apr 2011
    requirements by the EMA, immunogenicity assessments, a guide to the FDA's position and a section on pharmacovigilance, the report is an accurate state-of-play on a dynamic and shifting industry. The reports ...
  • PK Assays for Biotherapeutics - Part 1

    Future Medicine Ltd, Mar 2011 , Pages: 96
    combination biologics: analytical challenges related to pharmacokinetic assays and interpretation of pharmacokinetic and immunogenicity results Lauren Stevenson, et al - Dual ligation hybridization assay for ...
  • India Biosimilar Market Analysis

    Kuick Research, Aug 2012 , Pages: 80
    serious health issues. One of the key challenges regarding biosimilar products is immunogenicity. Studies that compare innovator biologics and biosimilars often report differences in aggregate levels ...
  • Next-Generation Biologics: Improving on Monoclonal Antibodies

    Decision Resources, Inc, Dec 2007 , Pages: 35
    and Royalty Stacking Delivery Immunogenicity Industry Interest and Clinical Development Remaining Challenges for MAb Alternatives Appendix A. Types of Biologic Alternatives to Therapeutic ...
  • Business Strategies for Different Types of Biogenerics

    Decision Resources, Inc, Nov 2007 , Pages: 32
    nuances of specific biologics markets but also the long-term commitment they will be required to make when developing biogenerics and the significant capital investment that will be required to achieve ...
  • The Biogenerics Market Outlook: An Analysis of Market Dynamics, Growth Drivers and Leading Players

    Scripp Business Insights, Mar 2005
    companies will benefit from the advent of generic biologics and identifies the companies who have the most to lose by examining the risks associated with the leading biologic brands. By 2010, biologic ...
  • Production of Therapeutic Glycoproteins - Patent and Technology Report - Key Players, Innovators and Industry Analysis

    Dolcera, Nov 2011 , Pages: 78
    biotherapeutics is expected to open up, which is worth billions of dollars. Biosimilars or follow-on biologics of the original glycoprotein drugs has led to the marketing of ‘copies’ of these drugs, varying in ...
  • Protein Drugs - Global Strategic Business Report

    Global Industry Analysts, Inc, Aug 2010 , Pages: 524
    Protein drugs, also referred to as biologics, are pharmaceuticals based upon proteins. Advent of proteomics and high-throughput screening has helped expand the range of protein drugs available for disease ...
  • Preclinical Development of Monoclonal Antibodies and Related Biologicals: Emerging Technologies and New Therapeutic Candidates

    Scripp Business Insights, Mar 2010 , Pages: 392
    . Key findings from this report - Early challenges relating to immunogenicity, tissue penetration, administration and production of monoclonal antibodies are being addressed by myriad new technologies ...
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