Advances in Medicinal Chemistry, Vol 5

  • ID: 1756499
  • Book
  • 200 Pages
  • Elsevier Science and Technology
1 of 4

Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.

Please Note: This is an On Demand product, delivery may take up to 11 working days after payment has been received.

Note: Product cover images may vary from those shown
2 of 4
Preface. Immunophilins: the next generation. Discovery of ABT-594 and related neuronal nicotinic acetylcholine receptor modulators as analgesic agents: medicinal chemistry and biology. Discovery and preclinical evaluation of novel dopamine partial agonists as antipsychotic agents. Nonpeptide inhibitors of HIV protease.
Note: Product cover images may vary from those shown
3 of 4

Loading
LOADING...

4 of 4
Reitz, A.B.
Dax, S.L.
Note: Product cover images may vary from those shown
5 of 4
Note: Product cover images may vary from those shown
Adroll
adroll