First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume reviews recent advances in the formation of endogenous cannabinoids and their receptors, metabolism and relation to disease processes.
*Longest running series published by Academic Press *Contributions by leading international authorities
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Table of Contents
Y. Okamoto, K. Tsuboi and N. Ueda, Enzymatic formation of anandamide
M.L. Yates and E.L. Barker, Organized trafficking of anandamide and related lipids
G.P. Mueller and W.J. Driscoll, Biosynthesis of oleamide
C.E. Goodfellow and M. Glass, Anandamide receptor signal transduction
A.J. Brown and C.R. Hiley, Is GPR55 an anandamide receptor?
E. Fride, N. Gobshtis, H. Dahan, A. Weller, A. Giuffrida and S. Ben-Shabat, The endocannabinoid system during development; emphasis on perinatal events and delayed effects
M. Bifulco, A. Santoro, C. Laezza and A.M. Malfitano, Cannabinoid receptor CB1 antagonists: state of the art and challenges
H.B. Bradshaw, N. Rimmerman, S.S.-J. Hu, S. Burstein and the late J.M. Walker, Novel endogenous N-acyl glycines: Identification and characterization
F.G. Correa, L. Mestre, F. Docagne, J. Borrell and C. Guaza, The endocannabinoid anandamide: from immunomodulation to neuroprotection, implications for multiple sclerosis
P. Grimaldi, G. Rossi, G. Catanzaro and M. Maccarrone, Modulation of the endocannabinoid-degrading enzyme fatty acid amide hydrolase by follicle-stimulating hormone
R. Malcher-Lopes and M. Buzzi, Glucocorticoid-regulated crosstalk between arachidonic acid and endocannabinoids biochemical pathways coordinates cognitive-, neuroimmune- and energy homeostasis-related adaptations to stress
L. Zhang and W. Xiong, Modulation of the Cys-loop ligand-gated ion channels by fatty acid and cannabinoids
D. McHugh and R.A. Ross, Endogenous cannabinoids and neutrophil chemotaxis
R. Pierantoni, G. Cobellis, R. Meccariello, G. Cacciola, R. Chianese, T. Chioccarelli and S. Fasano, CB1 activity in male reproduction: mammalian and non-mammalian animal models
A. Toth, P.M. Blumberg and J. Boczan, Anandamide and the vanilloid receptor (TRPV1)
L.B.M. Resstel, F.A. Moreira and F.S. Guimaraes, Endocannabinoid system and fear conditioning
N. Pasquariello, S. Oddi, M. Malaponti and M. Maccarrone, Regulation of gene transcription and keratinocyte differentiation by anandamide
G. Alpini and S. DeMorrow, Changes in the endocannabinoid system may give insight into new and effective treatments for cancer
R. Panday, V. Hegde, N. Singh, L. Hofseth, U. Singh, S. Ray, M. Nagarkatti and P. Nagarkatti, Use of cannabinoids as a novel therapeutic modality against autoimmune hepatitis
Trained in biochemistry at the University of Wisconsin, Madison, Dr. Litwack worked on enzymology and the effects of hormones on enzyme systems. Then he was a Postdoctoral Fellow of the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. Dr. Litwack's first position was as Assistant Professor of Biochemistry at Rutgers University in 1954. Six years later, he joined the University of Pennsylvania as associate professor and four years later went to the Fels Institute for Cancer Research and Molecular Biology, as full professor, eventually becoming Deputy Director of the Institute. In 1991, he accepted the Chair of Pharmacology at Thomas Jefferson University where he is also Deputy Director of the Jefferson Cancer Institute and Associate Director for Basic Science in the Jefferson Cancer Center. Dr. Litwack's work has been in the area of mechanisms of steroid receptor action involving especially the glucocorticoid and mineralocorticoid receptors, immunophi.