- Covers anesthetics and cardiac function- Addresses disorders of the cardiovascular system and associated diseases- Explains therapeutic and pathophysiological implications- Details reflex regulation of peripheral circulation- Includes full descriptions of the latest methodologies- Written by internationally recognized experts in the field of anesthesia research
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Cellular Targets:D. Kosk-Kosicka, Plasma Membrane Ca2+-ATPase as a Target for Volatile Anesthetics.J.E. Fletcher and V.E. Welter, Enhancement of Halothane Action at the Ryanodine Receptor by Unsaturated Fatty Acids.D.A. Schwinn, Adrenergic Receptors: Unique Localization in Human Tissues.A.S. Evers and M.D. Hossain, Volatile Anesthetic Effects on Inositol Triphosphate-Gated Intracellular Calcium Stores in GH3 Cells.
Reflex Regulation:J.L. Seagard, Differential Control of Blood Pressure by Two Subtypes of Carotid Baroreceptors.T.J. Ebert and M. Muzi, Sympathetic Activation with Desflurane in Humans.M. Muzi and T.J. Ebert, Randomized, Prospective Comparison of Halothane, Isoflurane, and Enflurane on Baroreflex Control of Heart Rate in Humans.L.B. Bell, Baroreflex Modulation by Isoflurane Anesthesia in Normotensive and Chronically Hypertensive Rabbits. Peripheral Circulation:T.A. Stekiel, L.B. Bell, Z.J. Bosnjak, and J.P.Kampine, Effects of Isoflurane on Regulation of Capacitance Vessels under Normotensive and Chronically Hypertensive Conditions.J.B. McCallum, T.A. Stekiel, A. Stadnicka, Z.J. Bosnjak, and J.P. Kampine, Effect of Volatile Anesthetics on Baroreflex Control of Mesenteric Venous Capacitance.M. Wood, Effect of General Anesthesia on Modulation of Sympathetic Nervous System Function.M. Jeng, J.L. Hart, S. Bina, and S.M. Muldoon, Inhibition of Nitric Oxide-Dependent Vasodilation by Halogenated Anesthetics.Q.H. Hogan, A. Stadnicka, and J.P. Kampine, Effects of Epidural Anesthesia on Splanchnic Capacitance.P.A. Murray, Anesthetic Modulation of Pulmonary Vascular Regulation.R. Dueck, Pulmonary Mechanics Changes Associatedwith Cardiac Surgery.W.M. Zapol and W.E. Hurford, Inhaled Nitric Oxide in Adult Respiratory Distress Syndrome and Other Lung Diseases.D.L. Roerig, S.B. Ahlf, C.A. Dawson, J.H. Linehan, and J.P. Kampine, First Pass Uptake in the Human Lung of Drugs Used during Anesthesia.Y. Huang, J.B. Yee, W.-H. Yip, and K.C. Wong, Lactic Acidosis and pH on the Cardiovascular System.
Cerebral Circulation:L.E. Moore and R.J. Traystman, Role of Oxygen Free Radicals and Lipid Peroxidation in Cerebral Reperfusion Injury.A. Hudetz, J.G. Lee, J.J. Smith, Z.J. Bosnjak, and J.P. Kampine, Effects of Volatile Anesthetics on Cerebrocortical Laser Doppler Flow: Hyperemia, Autoregulation, Carbon Dioxide Response, Flow Oscillations, and Role of Nitric Oxide.M.M. Todd, Cerebral Blood Flow during Isovolemic Hemodilution: Mechanistic Observations.B. Hindman, Cerebral Physiology during Cardiopulmonary Bypass: Pulsatile versus Nonpulsatile Flow.W.T. Schmeling and N.E. Farber, Anesthetic Actions of Cardiovascular Control Mechanisms in the Central Nervous System.
Contents of Previous Volumes.