Automation, edited by two of the leading experts in the field, presents the very latest experimental techniques explained in detail. This book has succeeded in bringing together researchers at the forefront of clone library construction, genome analysis, sequencing, computational data evaluation and functional analysis, to provide insight into this "new age" of research based on genomic and chemical screening.
Describes automated procedures used in microbiology and molecular biology
Includes developments in robotics and vision systems
Features automation in library picking, presentation and analysis
Discusses paralogous duplications in microbial genomes
Covers deciphering genomes through automated large-scale sequencing
Describes and stresses the need for functional analyses
Internationally acclaimed contributors, including Professor Leroy Hood
U. Pettersson, Introduction.
A. Fife and D.W.M. Crook, Automation in Clinical Microbiology.
A.J.McCollum, Vision Systems for Automated Colony and Plaque Picking.
D.R. Bancroft, E. Maier and H. Lehrach, Library Picking, Presentation and Analysis.
G. Kauer and H. Blöcker, The PREPSEQ Robot: An Integrated Environment for Fully Automated and Unattended Plasmid Preparations and Sequencing Reactions.
A.N. Hale, Building Realistic Automated Production Lines for Genetic Analysis.
A.N. Hale, Examples of Automated Genetic Analysis Developments.
L. Rowen, S. Lasky and L. Hood, Deciphering Genomes Through Automated Large-scale Sequencing.
N.C. Hauser, M. Scheideler, S. Matysiak, M. Vingron and J.D. Hoheisel, DNA Arrays for Transcriptional Profiling.
K.-J. Reiger, G. Orlowska, A. Kaniak, J.-Y. Coppee, G. Alijinovic and P.P. Slonimski, Large-scale Phenotypic Analysis in Microtitre Plates of Mutants with Deleted Open Reading Frames From Yeast Chromosome III: Key-step Between Genomic Sequencing And Protein Function.
J.J. Codani, J.P. Comet, J.C. Aude, E. Glémet, A. Wozniak, J.L. Risler, A. Hénaut and P.P. Slonimski, Automatic Analysis of Large-scale Pairwise Alignments of Protein Sequences.
M.Y. Galperin and D. Frishman, Towards Automated Prediction of Protein Function from Microbial Genomic Sequences.
Hoheisel, J?rg D.
Jorg D. Hoheisel received his Ph.D. in 1988 from the University of Konstanz, Germany, where he studied DNA structures. He was at the ICRF in London, UK from 1988 to 1993, working on genome analysis. Since 1993, he has been Head at the DKFZ (Deutsches Krebsforschungzentrum) in Heidelberg, Germany.