Cancer and Development, Vol 94. Current Topics in Developmental Biology

  • ID: 1757888
  • Book
  • 384 Pages
  • Elsevier Science and Technology
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In recent years, a number of molecular pathways and cellular processes that are essential for normal vertebrate development have been implicated in cancer initiation and progression. In this volume, leaders in the field of cancer genetics and developmental biology share recent insights into the importance of developmental pathways for tumorigenesis. These discoveries provide important avenues for innovative new approaches to treating some of the most challenging developmental tumors.

  • Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area
  • There are now a large number of molecular targeted therapies for the treatment of cancer. Many of these therapies target pathways that are essential for normal development. Therefore, this volume provides an up-to-date and timely perspective on those pathways and biological processes that hold the greatest promise for targeted intervention.

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  1. Childhood Cancer and Developmental Biology: A Crucial Partnership
    Dyer, MA
  2. Stem Cells in Brain Tumor Development
    Parada, L
  3. MDM2 and MDMX in Cancer and Development
    Marine, J-C
  4. The Connections between Neural Crest Development and Neuroblastoma- Lahti, J
  5. Rb1, development, and cancer
    Goodrich. D
  6. Genetic alterations targeting lymphoid development in acute lymphoblastic leukemia
    Mullighan, C
  7. Myogenesis and rhabdomyosarcoma: The Jekyll and Hyde of skeletal muscle
    Saab, R, Spunt, S and Skapek, S
  8. Medulloblastoma
    Roussel, MF and Hattan, ME
  9. Rethinking Pediatric Gliomas as Developmental Brain Abnormalities
    Gutmann, DH
  10. Tumor macrophages: protective and pathogenic roles in cancer development
    Murray, P. J.
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Dyer, Michael.

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