Cofactor Biosynthesis: A Mechanistic Perspective, Vol 61. Vitamins and Hormones

  • ID: 1758567
  • Book
  • 361 Pages
  • Elsevier Science and Technology
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The longest running serial published by Academic Press continues its well-respected run with Volume 61, a special volume in which a guest editor has come on board and has assembled some well-known contributors who are international authorities in the field. Together they tackle some of the latest topics in the field such as riboflavin and folate biosynthesis, biotin and lipoic acid biosynthesis, nicotinamide adenine dinucleotide biosynthesis, biosynthesis of vitamin B6 and structurally related derivatives, pantothenic acid and coenzyme A biosynthesis, mechanistic biosynthesis of protein-derived redox cofactors, ascorbic acid biosynthesis, biosynthesis of menaquinone and ubiquinone - Vitamin B12 biosynthesis, biosynthesis of the methanogenic cofactors, and thiamin biosynthesis.
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Preface.
Biosynthesis of Riboflavin, A. Bacher, S. Eberhardt, W. Eisenreich, M. Fischer, S. Herz, B. Illarionov, K. Kis, and G. Richter.
Biosynthesis of Biotin and Lipoic Acid, A. Marquet, B.T.S. Bui, and D. Florentin.
The Biosynthesis of Nicotinamide Adenine Dinucleotides in Bacteria, T. Begley, C. Kinsland, R.A. Mehl, A. Osterman, and P. Dorrestein.
Biosynthesis of Vitamin B6 and Structurally Related Derivatives, C. Drewke and E. Leistner.
The Biosynthesis of Coenzyme A in Bacteria, T. Begley, C. Kinsland, and E. Strauss.
Biosynthesis of Menaquinone (Vitamin K2) and Ubiquinone (Coenzyme Q): A Perspective on Enzymatic Mechanisms, R. Meganathan.
Mechanisms of Biosynthesis of Protein-Derived Redox Cofactors, B. Schwartz and J.P. Klinman.
L-Ascorbic Acid Biosynthesis, N. Smirnoff.
Multiple Biosynthetic Pathways for Vitamin B12: Variations on a Central Theme, C.A. Roessner, P.J. Santander, and A.I. Scott.
Biosynthesis of the Methanogenic Cofactors, R.H. White.
Appendixes.
Index.
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Litwack, Gerald.
Trained in biochemistry at the University of Wisconsin, Madison, Dr. Litwack worked on enzymology and the effects of hormones on enzyme systems. Then he was a Postdoctoral Fellow of the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. Dr. Litwack's first position was as Assistant Professor of Biochemistry at Rutgers University in 1954. Six years later, he joined the University of Pennsylvania as associate professor and four years later went to the Fels Institute for Cancer Research and Molecular Biology, as full professor, eventually becoming Deputy Director of the Institute. In 1991, he accepted the Chair of Pharmacology at Thomas Jefferson University where he is also Deputy Director of the Jefferson Cancer Institute and Associate Director for Basic Science in the Jefferson Cancer Center. Dr. Litwack's work has been in the area of mechanisms of steroid receptor action involving especially the glucocorticoid and mineralocorticoid receptors, immunophi.
Begley, Tadgh.

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