Development of T Cell Immunity, Vol 92. Progress in Molecular Biology and Translational Science

  • ID: 1759565
  • Book
  • 342 Pages
  • Elsevier Science and Technology
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T cells belong to a group of white blood cells called lymphocytes and play a large role in the immune response. An increased understanding of T cell immunity will provide new insights into the etiology of human autoimmune disease such as diabetes.

This volume reviews the latest developments and discusses the evolution of T cell immunity, thymic requirements, and how to prevent T cell-dependent autoimmunity.

  • Discusses new discoveries, approaches, and ideas in T cell immunity
  • Contributions from leading scholars and industry experts
  • Reference guide for researchers involved in molecular biology and related fields
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Development of T cell immunity

- The development of T cell immunity
Adrian Liston

The evolution of T cell immunity

- Genome duplication and T cell immunity
Masanori Kasahara

- Questions arising from "Genome duplication and T cell immunity" - Claude Perreault

- Response to questions
Masanori Kasahara

- The origin and role of MHC class I-associated self peptides
Claude Perreault

- Questions arising from "The origin and role of MHC class I-associated self peptides" - Masanori Kasahara

- Response to questions
Claude Perreault

Thymic requirements for T cell immunity

- Transcriptional regulation of thymus organogensis and thymic epithelial cell differentiation
Nancy Manley and Brian Condie

- Early T cell differentiation: lessons from T-cell acute lymphoblastic leukemia
Cedric S Tremblay, Thu Hoang and Trang Hoang

T cell immunity in the periphery

- Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses
Peter J L Lane, Fiona M McConnell, David Withers, Fabrina Gaspal, Manoj Saini and Graham Anderson

- Commentary on "Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses" - Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes

- Cellular and Molecular Requirements in Lymph Node and Peyer's Patch Development
Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes

- T follicular helper cells during Immunity and Tolerance
Michelle A. Linterman and Carola G. Vinuesa

Preventing T cell-dependent autoimmunity

- Thymic selection and lineage commitment of CD4+Foxp3+ regulatory T cells
Paola Romagnoli and Joost P.M. van Meerwijk

- Molecular Mechanisms of Regulatory T cell Development and Suppressive Function
Jeong M. Kim

- Is Foxp3 the master regulator of regulatory T cells? - Adrian Liston
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Liston, Adrian.

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