The book will be essential reading for all researchers and postgraduate research students in molecular genetics, clinical genetics, and molecular biology, but also those involved in ophthalmology, public health, medical statistics, and mathematics.
The volume covers:
- Introduction and History
- Linkage in Dominant Recessive and Oligogenic Disease
- Model Free (Non-Parametric) Methods
- Tools (for Gene Mapping)
Linkage in Dominant, Recessive, and Polygenic Disease:N.E. Morton and P. Lio, Oligogenic Linkage and Map Integration.J. Ott, Genetic Mapping in Complex Disorders.J.H. Edwards, Recessive Disease and Allelic Association.T. Grimm, Mutation-Selection-Equilibria, Genetic Models, and Linkage Analysis.D. Stephens and C.A.B. Smith, Simple Likelihood and Probability Calculations for Linkage Analysis.