- Integrates theoretical and practical issues related to stress and addiction- Includes case studies illustrating where an emotional state and addictive behavior represent a prominent feature of the clinical presentation- Cross-disciplinary coverage with contributions by by scientists and practitioners from multiple fields, including psychology, neuroscience, neurobiology, and medicine
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Section I. Neurobiology of Stress and Addiction.
Biological Bases of the Stress Response.
The Hypothalamic-Pituitary-Adrenal Axis and Addiction.
Dopaminergic Reward Pathways and Effects of Stress.
Endogenous Opiates, Addiction, and the Stress Response.
Early Life Stress and Vulnerability to Addiction.
Genetics, Stress and the Risk for Addiction .
Neurobiology of Stress and Risk for Relapse.
Section II. Psychosocial Processes Related to Stress and Addiction.
Negative Affect and Addiction.
Stress and Impulsive Behaviors.
Psychosocial Determinants of the Stress Response.
Individual Differences in Response to Stress and Risk for Addiction.
Addiction and Stress in Adolescents.
Section III. Clinical Implications: Assessment and Intervention.
The Assessment of Stress in Research and Clinical Settings.
Assessment of Addictions in Clinical and Research Settings.
Stress, Anxiety and Addiction: Intervention Strategies.
Posttraumatic Stress Disorder and Substance Use Disorders.
Novel Pharmacologic treatment of Stress and Addiction: The Role of CRF and Glucocorticoid Antagonists.
Future directions of research on stress and addictive behaviors.
Professor of Behavioral Medicine and holder of the Max & Mary La Due Pickworth Chair at the University of Minnesota Medical School, Dr. al'Absi is the founding director of the Duluth Medical Research Institute. He is also the Course Director of Behavioral Medicine at the Medical School, has a joint appointment as a Professor and a graduate faculty at the Departments of Physiology & Pharmacology, Neuroscience, Family Medicine, and the Integrated Biological Sciences Program. Professor al'Absi directs a research program focusing on the neurobiology of stress.