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T Cell Subsets, Vol 83. Advances in Immunology

  • ID: 1764106
  • Book
  • 304 Pages
  • Elsevier Science and Technology
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This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.

T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers

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Early Lymphoid Progenitor Subsets
Lineage Commitment and Developmental Plasticity
The CD4/CD8 Lineage Choice: New Insights
Analysis of the CD4/CD8 Lineage Decision
Development and Function of T Helper 1 Cells
Th2 cells: Orchestrating Barrier Immunity
Memory T. Cells -Generation, Maintenance, and Function
An Integrated Model of Immunoregulation
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Alt, Frederick W.
Cantor, H.
Glimcher, Laurie.

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