The Zebrafish: Disease Models and Chemical Screens, Vol 105. Edition No. 3. Methods in Cell Biology

  • ID: 1764975
  • Book
  • 616 Pages
  • Elsevier Science and Technology
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This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish.
  • Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls
  • This volume concentrates on Disease Models and Chemical Screens
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Part I: Disease Models

1. Germ Cell Tumors in Zebrafish
Jim Armatruda

2. Schwann Cell Myelination Mutants as Models of Multiple Sclerosis
David Lyons

3. In Vivo Analysis of Zebrafish Adipogenesis
John Rawls. First draft Sept. 1.

4. Host-Microbe Interactions in the Zebrafish
Karen Guillemin (University of Oregon)

5. Hematopoietic Stem Cell Development and Blood Flow
Trista North

6. Zebrafish as a Model for Hemorrhagic Stroke
Brant Weinstein

7. Zebrafish Adaptive Immunity: Structure and Function of Physiologic Development and Malignant Transformation
Nikolaus Trede and David Traver

8. Zebrafish VHL Disease Model
Freek van Eeden and co-authors Received 8/7/10.

9. Muscle Diseases
Peter Curie and Lou Kunkel

10. Basement Membrane Diseases
Natália M. Feitosa, Tom Carney, Matthias Hammerschmidt

11. Lymphangiogenesis

12. Osteogenesis

13. Zebrafish Assays of Ciliopathies
Nicholas Katsanis, JHU Sch of Med and Norann Zaghloul (UMD)

14. Infectious Disease: Innate Immunity
Herman Spaink

15. Tuberculosis
Lalita Ramakrishnan

16. Cancer
Tom Look

17. Melanoma
Patton and Schartl

18. Pancreatic Cancer
Steve Leach

19. Rhabdomyosarcoma
David Langenau MS Approved by Monte July 31.

20. Transplantation in Zebrafish
Pulin Li and Len Zon

21. Modeling Human Disease by Gene Targeting
Andrew Dodd, Stephen Chambers, Peter Nielsen, and Donald Love

22. Fluorescent Imaging of Cancer
David Langenau

23. Zebrafish as a Model for Fanconi's Anemia
John Postlethwait

Part II: Chemical Screens

1. Chemical Screens for Potential Therapeutics
Justin Lee Hong Tan and Len Zon

2. Psychotropic Drug Discovery by Automated Behavioral Phenotyping
Randall Peterson resent June 15

3. Discovery and Use of Small Molecules for Probing Biological Processes
Randall Peterson and Mark Fishman

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Detrich, III, H. William.
Professor of Biochemistry and Marine Biology at Northeastern University, promoted 1996. Joined Northeastern faculty in 1987. Previously a faculty member in Dept. of Biochemistry at the University of Mississippi Medical Center, 1983-1987.Principal Investigator in the U.S. Antarctic Program since 1984. Twelve field seasons "on the ice" since 1981. Research conducted at Palmer Station, Antarctica, and McMurdo Station, Antarctica.Research areas: Biochemical, cellular, and physiological adaptation to low and high temperatures. Structure and function of cytoplasmic microtubules and microtubule-dependent motors from cold-adapted Antarctic fishes. Regulation of tubulin and globin gene expression in zebrafish and Antarctic fishes. Role of microtubules in morphogenesis of the zebrafish embryo. Developmental hemapoiesis in zebrafish and Antarctic fishes. UV-induced DNA damage and repair in Antarctic marine organisms.
Westerfield, Monte.
Zon, Leonard I.

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