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Leucocyte Adhesion, Vol 64. Current Topics in Membranes

  • ID: 1767368
  • Book
  • November 2009
  • 300 Pages
  • Elsevier Science and Technology
Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. This volume provides a review of the latest developments in leukocyte adhesion. Regulation of cell adhesion is important for immune system function.

- Contributions from leading experts in the field- Reviews the latest developments

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1. Membrane composition and properties

- Lipid rafts (open)

- Membrane tethers (R Waugh, Rochester)

- Microvilli (JY Shao, Wash U)

- Whole cell deformation (D Khismatullin, Tulane)

2. Adhesion molecules

- Integrin activation (M. Shimaoka, Harvard)

- Cytoskeletal anchoring (Fred Pavalko, Iowa)

- No tile yet (Alon, Weizman)

- Catch bonds (Cheng Zhu, Georgia Tech and Roger McEver, OMRF)

- Modeling adhesion (Pospieszalska/Ley, LIAI)

- Factors limiting the onset of bond formation at cell interfaces (R Waugh, Rochester)

3. Active role of endothelial cells

- Adhesive platforms (O. Barreiro, Madrid)

- Migratory cups, podosomes (Chris Carman, Beth Israel)

- PECAM recycling (WA Muller, Northwestern)

4. Methods

1. FRET (Minsoo Kim, Rochester)

2. Flow chambers (Simon SI at UC Davis)
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Ley, Klaus
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