Osteoporosis in Men. Edition No. 2

  • ID: 1769133
  • Book
  • 741 Pages
  • Elsevier Science and Technology
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Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men.

This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger - 8.5 x 11. This edition  of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy.

  • Brings together more eminent investigators and clinicians to interpret developments in this growing field.
  • Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy.
  • There is no book on the market that covers osteoporosis in men as comprehensively as this book.
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Section 1
Essentials of bone biology

- The Biochemistry of Bone: Composition and Organization

Adele L. Boskey

- Bone Remodeling: Cellular Activities in Bone

David W. Dempster, Hua Zhou, Shi Shou Lu

- Assessment of Bone Turnover Using Biochemical Markers

Patrick Garnero, Pawel Szulc

- Fundamentals of Mineral Homeostasis

David A. Hanley, Shawn K. Davison

- The Mechanical Properties of Bone

David P. Fyhrie

- Assessment of Bone Architecture

Thomas F. Lang

Section 2
Development and growth of the male skeleton

- Skeletal Growth in Males

Qingju Wang, Ego Seeman

- Pubertal Growth of the Male Skeleton

Vincent Gilsanz, Stefano Mora

- The Effects of Sex Steroids on Bone Growth

Giampiero I. Baroncelli, Silvano Bertelloni

- Nutritional Basis of Skeletal Growth

Connie M. Weaver, Elizabeth Haney

- Physical Activity and Skeletal Growth

Heather M. Macdonald, Heather A. McKay, Melonie Burrows

Section 3
Skeletal genetics

- The Genetics of Peak Bone Mass

Luigi Gennari, Robert F. Klein, Serge Ferrari

Section 4
Aging and the male skeleton

- Age-Related Changes in Bone Remodeling and Micro Architecture

Roger Zebaze, Ego Seeman

- Markers of Bone Remodeling and the Aging Skeleton

Serge Cremers, Christian Meier, Markus J. Seibel

- Alterations in Mineral Metabolism in the Aging Male

Shonni J. Silverberg, Bismruta Misra

- Change in Bone Size and Geometry with Aging

Pawel Szulc

- Aging and Bone Density

Steven Boonen, Filip Callewaert, Katrien Venken, Dirk Vanderschueren

- The Effect of Age on Material Properties

Charles H. Turner, Matt Allen, David Burr

Section 5, Nutritional issues

- Calcium, Bone Strength and Fractures

Laura A.G. Armas, David P. Heaney, Joan M. Lappe

- Vitamin D and Bone

Roger Bouillon, Christa Maes, Lieve Verlinden, Geert Carmeliet, Annemieke Verstuyf

- Role of Dietary Protein in Bone Growth and Bone Loss

Rene Rizzoli

Section 6
Sex steroids and the skeleton in men

- The Molecular Biology of Sex Steroids in Bone: Similarities and Differences Among the Sexes

Stavroula Kousteni

- Estrogen and the Skeleton
Rodents

Dirk Vanderschueren, Katrien Venken, Filip Callewaert, Steven Boonen

- Estrogen and the Skeleton
Humans

Liesbeth Vandenput, Claes Ohlsson

- Androgens and the Skeleton
Animal Models

Kristine Wiren, Eric Orwoll

- Androgens and the Skeleton
Humans

Benjamin Z. Leder

- Androgen Effects on the Skeletal Muscle

Shalender Bhasin, Rajan Singh, Ravi Jasuja, Thomas W. Storer

Section 7
Fractures in men

- Epidemiology of Fractures

Shreyasee Amin

- Individualized Progress of Fractures in Men

Tuan V. Nguyen , John A. Eisman

- Physical Activity, Physical Function and Fall and Fracture Risk in Older Men

Peggy Mannen Cawthon, Lynn Marshall

- Economic Impact of Osteoporotic Fractures (vs women)

Terence O'Neill

- Adverse Health Outcomes in Men with Osteoporosis

Deborah T. Gold, Stuart L. Silverman

Section 8. Metabolic bone disease in men

- Idiopathic Osteoporosis

Jean-Marc Kaufman, Bruno Lepauw, Youri Taes, Stefan Goemeare

- Glucocorticoid Induced Osteoporosis

Andrea Giustina, Gherardo Mazziotti

- Testicular Dysfunction

David J. Handelsman, Christian Meier, Markus J. Seibel

- Alcohol and Bone

Neil Binkley

- Transplantation Osteoporosis

Elizabeth Shane, Juliet E. Compston, Emily Stein

- Management of Fractures in Men with Impaired Renal Function

Paul D. Miller

- Hyperparathyroidism

John P. Bilezikian, Claudio Marccoci

- Hypercalciuria

Murray J. Favus

- The Skeletal Phenotype of the Male Athlete

Clifford J. Rosen, Ann E. Maloney

- Inherited and Related Disorders of Bone Matrix Synthesis in Men

Jay R. Shapiro

Section 9
Diagnostic approach

- Dual-Energy X-ray Absorptiometry (DXA) in Men

Neil C. Binkley, Robert A. Adler

- Quantitative Ultrasound Diagnosis of Osteoporosis in Men

Robert A. Adler, Neil C. Binkley

- Advanced Structural Assessment of Bone Using CT and MRI

X. Edward Guo, X. Sherry Liu, Felix W. Wehrli

- Vertebral Fracture Assessments

Piet Geusens, Willem Lems

- The Use of Bone Biopsies in the Diagnosis of Male Osteoporosis

Erik F. Eriksen, Johan Halse

- Overall diagnostic strategy

Eric Orwoll

Section 10
Therapy

- Diagnostic Thresholds for Osteoporosis in Men

John A. Kanis, Anders Oden, Helena Johansson, Eugene V. McCloskey

- Cost-Effectiveness of Interventions to Reduce Osteoporosis-Related Fractures in Men: Current Data, Controversies, and Challenges

John T. Schoesboe

- Nutritional Therapy for Skeletal Health in Men

Deborah E. Sellmeyer, Diana M. Antoniucci

- Exercise Programs for Patients with Osteoporosis

Dieter Felsenberg, Martin Runge

- Calcitonin: History, Physiology, Pathophysiology and Therapeutic Applications

Sunil J. Wimalawansa

- Treatment of Male Osteoporosis with Bisphosphonates

Socrates E. Papapoulos, Andrea Giusti

- Treatment of Male Osteoporosis with Parathyroid Hormone

Monica Giotra, Felicia Cosman, John P. Bilezikian

- Testosterone Therapy for Osteoporosis in Men

Kishore M. Lakshman, Andre B. Araujo, Shalendar Bhasin

57. Future Therapies: Strontium, SERMs, SARMs and New Therapies on the Horizon

Ghada El-Hajj Fuleihan, Mahmoud Tabbal
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Orwoll, Eric S.
Professor of Medicine and Director, Clinical Research Center, Division of Endocrinology, Diabetes and Clinical Nutrition, Oregon Health & Science University, Portland, Oregon
Bilezikian, John P.
John P. Bilezikian, MD, the Dorothy L. and Daniel H. Silberberg Professor of Medicine and Professor of Pharmacology at the College of Physicians & Surgeons, Columbia University is Chief of the Division of Endocrinology and Director of the Metabolic Bone Diseases Program at Columbia University Medical Center. Dr. Bilezikian received his undergraduate training at Harvard College and his medical training at the College of Physicians & Surgeons. He completed four years of house staff training (internship, residency and Chief Residency) on the Medical Service at Columbia Presbyterian Medical Center. Dr. Bilezikian received his training in Metabolic Bone Diseases and in Endocrinology at the NIH in the Mineral Metabolism Branch under the tutelage of Dr. Gerald Aurbach. Dr. Bilezikian belongs to a number of professional societies including the American Society for Bone and Mineral Research, of which he served as President, 1995-1996 and the International Society of Clinical Densitometry, of which he served as President, 1999-2001. He serves on the Board of Governors of the International Osteoporosis Foundation (1998-present) and on its Committee of Scientific Advisors (2001-present). He is Chair of the Endocrine Fellows Foundation. He served as Editor-in-Chief of the Journal of Clinical Endocrinology and Metabolism (2000-2004) and as Senior Associate Editor of the Journal of Bone and Mineral Research (2008-2012). He is Executive Advisory Editor of Bone Research (2013-present). His books include Editor-in-Chief of The Parathyroids [1994, 2001, 2014], and co-editor of The Aging Skeleton (1999), Dynamics of Bone and Cartilage Metabolism (1999, 2006), Principles of Bone Biology (1996, 2002, 2008) and Osteoporosis in Men (2010). He served as co-chair of the last three NIH Workshops on Primary Hyperparathyroidism (2002, 2008, 2013). He is the recipient of the Distinguished Physician Award of the Endocrine Society, the Frederic C. Bartter Award of the American Society for Bone and Mineral Research (ASBMR) for Excellence in Clinical Research and the First Annual Global Leadership Award of the International Society of Clinical Densitometry. In 2009, he received the Gideon A. Rodan Excellence in Mentorship Award from the ASBMR. He received the Laureate Distinguished Educator Award of The Endocrine Society in 2014. In 2014, he was made honorary member of the Brazilian Society of Endocrinology and Metabolism. His publications number over 700.
Vanderschueren, Dirk
Professor of Medicine, Division of Endocrinology, Department of Internal Medicine, UZ Gasthuisberg, Leuven, Belgium
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