The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.
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- The Central Role of 5-HT6 Receptors in Modulating Brain Neurochemistry Lee A Dawson
- 5-HT6 receptor memory and amnesia. Behavioral Pharmacology: Learning and Memory Processes Alfredo Meneses, Pérez-García G, Tellez R, Ponce-Lopez T and C Castillo
- Behavioral Pharmacology: Potential Antidepressant and Anxiolytic Properties Anna Wesolowska, Magdalena Jastrzebska-Wiesek
- The 5-Ht6 Receptor as a Target for Developing Novel Anti Obesity Drugs David Heal, Jane Gosden, and Sharon Smith
- Behavioral and neurochemical pharmacology of 5-HT6 receptors related to reward and reinforcement. Gaetano Di Chiara, Valentina Valentini and Sandro Fenu
- 5-HT6 Receptor Ligands and their Antipsychotic Potential Jørn Arnt and Christina Kurre Olsen
- 5-HT6 Receptor Ligands as Antidementia Drugs Ellen Siobhan Mitchell