Proteases in Health and Disease, Vol 99. Progress in Molecular Biology and Translational Science

  • ID: 1770145
  • Book
  • 328 Pages
  • Elsevier Science and Technology
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Proteases occur naturally in all organisms. They are enzymes that are involved in many physiological reactions such as digestion of food and blood clotting. This volume reviews their role in health and disease and presents the latest research and developments.

* Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

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Chapter 1: Membrane-Anchored Serine Proteases in Health and Disease

by Toni M. Antalis, Thomas Bugge, and Qingyu Wu

Chapter 2: Complex Assemblies of Factor IX and X Regulate the Initiation, Maintenance, and Shutdown of Blood Coagulation

by Thomas Zögg and Hans Brandstetter

Chapter 3: Structure and Proteolytic Properties of ADAMTS13, a Metalloprotease Involved in the Pathogenesis of Thrombotic Microangiopathies

by Stefano Lancellotti and Raimondo De Cristofaro

Chapter 4: Thrombin as an Anticoagulant

by Enrico Di Cera

Chapter 5: Regulation of Proteases by Protein Inhibitors of the Serpin Superfamily

by Steven T. Olson and Peter G.W. Gettins

Chapter 6: Multiple Roles of Metalloproteinases in Neurological Disorders

by Yi Yang, Jeff W. Hill, and Gary A. Rosenberg
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Di Cera, Enrico
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