Proteases occur naturally in all organisms. They are enzymes that are involved in many physiological reactions such as digestion of food and blood clotting. This volume reviews their role in health and disease and presents the latest research and developments.
* Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields
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by Toni M. Antalis, Thomas Bugge, and Qingyu Wu
Chapter 2: Complex Assemblies of Factor IX and X Regulate the Initiation, Maintenance, and Shutdown of Blood Coagulation
by Thomas Zögg and Hans Brandstetter
Chapter 3: Structure and Proteolytic Properties of ADAMTS13, a Metalloprotease Involved in the Pathogenesis of Thrombotic Microangiopathies
by Stefano Lancellotti and Raimondo De Cristofaro
Chapter 4: Thrombin as an Anticoagulant
by Enrico Di Cera
Chapter 5: Regulation of Proteases by Protein Inhibitors of the Serpin Superfamily
by Steven T. Olson and Peter G.W. Gettins
Chapter 6: Multiple Roles of Metalloproteinases in Neurological Disorders
by Yi Yang, Jeff W. Hill, and Gary A. Rosenberg