Beginning with an overview of metals and selected nonmetals in biology, the book then discusses the following concepts: basic coordination chemistry for biologists; structural and molecular biology for chemists; biological ligands for metal ions; intermediary metabolism and bioenergetics; and methods to study metals in biological systems.
The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment.
- Winner of a 2013 Textbook Excellence Awards (Texty) from the Text and Academic Authors Association
- Readable style, complemented by anecdotes and footnotes
- Enables the reader to more readily grasp the biological and clinical relevance of the subject
- Color illustrations enable easy visualization of molecular mechanisms
Basic coordination chemistry for biologists
Structural and molecular biology for chemists
Biological ligands for metal ions
An overview of intermediary metabolism and bioenergetics
Methods which can be used to study metals in biology
Metal assimilation pathways
Transport, storage and homeostasis of metal ions
Sodium and potassium
Nickel and cobalt
Molybdenum, vanadium, tungsten and chromium
Metals in brain function
Metals in medicine and the environment
Robert Crichton is Emeritus Professor, Faculty of Science, Universite Catholique de Louvain in Belgium. He has some forty years experience in teaching the subject, and published over 200 scientific articles and a number of books. Since 1985 he has organized a series of over twenty advanced courses on Metals in Biology in Louvain-la-Neuve, which have trained over 1300 doctoral and post-doctoral students, many of whom are today leaders in the field.
The Second Edition of Biological Inorganic Chemistry: An Introduction to Molecular Structure and Function received the 2013 TEXTY Textbook Excellence Award in Physical Sciences from the Text and Academic Authors Association.