From the Foreword by
E.J. Corey, Nobel laureate
An invaluable guide to name reactions on carbocyclic ring formations
Ring–forming reactions have found widespread applicability advantageous to the interests of science. Currently, they are used in all areas of organic synthesis, including medicinal and pharmaceutical, agricultural, fine chemicals, and, most recently, polymer science.
This all–inclusive reference focuses on name reactions specific to ring formations, and details the carbocyclic characteristics that make these rings an effective tool in the synthetic arsenal of organic chemistry with:
A description of a ring–forming reaction included in each section highlighting the following: historical perspective, a mechanism for the reaction, variations and improvements on the reaction, synthetic utilities of the reaction, experimental details, and current references
Coverage of fundamental topics, including various carbocycles (three, five, six, and large–ring carbocycles) and the transformation of carbocycles
Examples of common name reactions, such as Simmons–Smith, Pauson–Khand, Danheiser annulation, Diels–Alder, Robinson annulation, Stork enamine reaction, and ring–closing metathesis
An excellent resource for both students and professionals involved with organic chemistry and polymer synthesis, Name Reactions for Carbocyclic Ring Formations delivers essential information on the latest developments from leading experts in the field and serves as a springboard to further advance scientific discovery.
Chapter 1 Three–Membered Carbocycles.
1.1 Freund Reaction.
1.2 Kishner Cyclopropane Synthesis.
1.3 Kulinovich Cyclopropanol Synthesis.
1.4 Simmons–Smith Reaction.
Chapter 2 Four–Membered Carbocycles.
2.1 Staudinger Ketene Cycloaddition.
Chapter 3 Five–Membered Carbocycles.
3.1 Danheiser Annulation.
3.2 Dieckmann Condensation.
3.3 Favorskii Rearrangement.
3.4 Nazarov Cyclization.
3.5 Pauson–Khand Reaction.
3.6 Weiss Cook Reaction.
Chapter 4 Six–Membered Carbocycles.
4.1 Bardhan–Sengupta Pheantherene Synthesis.
4.2 Bergman Cyclization.
4.3 Bogert–Cook Reaction.
4.4 Bradsher Cycloaddition and Bradsher Reaction.
4.5 Bradsher Reaction.
4.6 Darzens Synthesis of Tetralin Derivatives.
4.7 Diels–Alder Reaction.
4.8 Dötz Benzannulation.
4.9 Elbs Reaction.
4.10 Fujimoto–Belleau Reaction.
4.11 Haworth Reaction.
4.12 Moore Cyclization.
4.13 Myers–Saito Cyclization.
4.14 Robinson Annulation.
4.15 Scholl Reaction.
Chapter 5 Large–Ring Carbocycles.
5.1 Buchner Reaction.
5.2 de Mayo Reaction.
5.3 Ring–closing Metathesis (RCM).
5.4 Thorpe–Ziegler Reaction.
Chapter 6 Transformations of Carbocycles.
6.1 Blanc Chloromethylation Reaction.
6.2 Asymmetric Friedel–Crafts Reactions: Past to Present.
6.3 Houben–Hoesch Reaction.
6.4 Kolbe–Schmitt Reaction.
6.5 Vilsmeier–Haack Reaction.
6.6 von Richter Reaction.
1 Contents Volume 1: Name Reactions in Heterocyclic Chemistry.
2 Contents Volume 2: Name Reactions for Functional Group Transformations.
3 Contents Volume 3: Name Reactions for Homologations Part I.
4 Contents Volume 4: Name Reactions for Homologations Part II.
5 Contents Volume 6: Name Reactions in Heterocyclic Chemistry Part II.