Name Reactions in Heterocyclic Chemistry II. Comprehensive Name Reactions

  • ID: 2171727
  • Book
  • 704 Pages
  • John Wiley and Sons Ltd
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The up–to–DATE guide to name reactions in heterocyclic chemistry

Name Reactions in Heterocyclic Chemistry II presents a comprehensive treatise on name reactions in heterocyclic chemistry, one of the most exciting and important fields within organic chemistry today.

The book not only covers fresh ground, but also provides extensive information on new and/or expanded reactions in:

  • Three– and four–membered heterocycles

  • Five–membered heterocycles (pyrroles and pyrrolidines, indoles, furans, thiophenes, and oxazoles)

  • Six–membered heterocycles, including pyridines, quinolines, and isoquinolines

Featuring contributions from the leading authorities in heterocyclic chemistry. Each section includes a description of the given reaction, as well as the relevant historical perspective, mechanism, variations and improvements, synthetic utilities, experimental details, and references to the current primary literature.

The reactions covered in Name Reactions in Heterocyclic Chemistry have been widely adopted in all areas of organic synthesis, from the medicinal/pharmaceutical field, to agriculture, to fine chemicals, and the book brings the most cutting–edge knowledge to practicing synthetic chemists and students, along with the tools needed to synthesize new and useful molecules.

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Foreword.

Preface.

Contributing Authors.

PART 1 THREE– AND FOUR–MEMBERED HETEROCYCLES.

Chapter 1 Aziridines and Epoxides.

1.1 Blum Aziridine Synthesis.

1.2 Gabriel Heine Aziridine Isomerization.

1.3 Shi Epoxidation.

PART 2 FIVE–MEMBERED HETEROCYCLES.

Chapter 2 Pyrroles and Pyrrolidines.

2.1 Clauson Kass Pyrrole Synthesis.

2.2 Houben Hoech Acylation of Pyrroles.

2.3 Overman Pyrrolidine Synthesis.

2.4 Trofimov Synthesis of Pyrroles.

Chapter 3 Indoles.

3.1 Bischler Möhlau Indole Synthesis.

3.2 Borsche Drechsel Cyclization.

3.3 Buchwald Hartwig Indole Synthesis.

3.4 Cadogan Sundberg Indole Synthesis.

3.5 Fukuyama Indole Synthesis.

3.6 Gassman Oxindole Synthesis.

3.7 Larock Indole Synthesis.

3.8 Matinet Dioxindole Synthesis.

3.9 Mori Ban Indole Synthesis.

3.10 Sandmeyer Isatin Synthesis.

3.11 Sommelet Hauser Rearrangement.

3.12 Stollé Oxindole Synthesis.

Chapter 4 Furans and Oxazoles.

4.1 Nierenstein Reaction.

4.2 Davidson Oxazole Synthesis.

4.3 Fischer Oxazole Synthesis.

4.4 Japp Oxazole Synthesis.

4.5 Schöllkopf Oxazole Synthesis.

Chapter 5 Other Five–Membered Heterocycles.

5.1 Bamberger Imidazole Cleavage.

5.2 Dimroth Triazole Synthesis.

5.3 Finnegan Tetrazole Synthesis.

5.4 Hantsch Thiazole Synthesis.

5.5 Huisgen Tetrazole Rearrangement.

5.6 Knorr Pyrazole Synthesis.

5.7 Pechmann Pyrazole Synthesis.

PART 3 SIX–MEMBERED HETEROCYCLES.

Chapter 6 Pyridines.

6.1 Baeyer Pyridine Synthesis.

6.2 Katrizky Reaction.

Chapter 7 Quinolines and Isoquinolines.

7.1 Betti reaction.

7.2 Bernthsen Acridine Synthesis.

7.3 Lehmstedt Tanasescu Reaction.

7.4 Niementowski Quinoline Synthesis.

7.5 Povarov Reaction.

Chapter 8 Six–Membered Heterocycles.

8.1 Balaban Nenitzescu Praill Reaction.

8.2 Borsche Cinnoline Synthesis.

8.3 Gutknecht Pyrazine Synthesis.

8.4 Niementowski Quinazoline Synthesis.

8.5 Pechmann Coumarin Synthesis.

8.6 Robinson Schöpf Condensation.

8.7 Simonis Chromone Cyclization.

8.8 Wesseley Moser Rearrangement.

8.9 Widman Stoermer Cinnoline Synthesis.

8.10 Wichterle Reaction.

Chapter 9 Miscellaneous Name Reactions.

9.1 ANRORC Mechanism.

9.2 Boulton Katritzky Rearrangement.

9.3 Chichibabin Amination Reaction.

9.4 Dimroth Rearrangement.

9.5 Hantzsch Synthesis.

9.6 Ortoleva King Reaction.

Appendices.

Appendix 1, Table of Contents for Volume 1: Name Reactions in Heterocyclic Chemistry.

Appendix 2, Table of Contents for Volume 2: Name Reactions for Functional Group Transformations.

Appendix 3, Table of Contents for Volume 3: Name Reactions for Homologations–I.

Appendix 4, Table of Contents for Volume 4: Name Reactions for Homologations–II.

Appendix 5, Table of Contents for Volume 5: Name Reactions for Ring Formations.

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Jie
Jack Li is a Chemist at Bristol–Myers Squibb Company. He has authored or edited various books, including the first volume of Name Reactions in Heterocyclic Chemistry, Name Reactions for Functional Group Transformations, Name Reactions for Carbocyclic Ring Formations, and several others, all published by Wiley.
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