An integrative, investigative approach to coordination chemistry
This book offers a series of investigative inorganic laboratory exercises approached through systematic coordination chemistry. After an introduction that provides an overview of complex coordination concepts, Integrated Approach to Coordination Chemistry: An Inorganic Laboratory Guide leads readers on a progressive, graduated exploration of experimentation in the inorganic field.
Core chapters cover: inorganic synthesis and quantitative analysis; molecular structure; substitution kinetics; and electron transfer reactions
Advanced topics emphasize major applications of coordination complexes that have emerged over the past several decades: metals in medicine, the environment, molecular biology, and organic synthesis
Each chapter features a project overview, at least five related experiments, and detailed references for further study
The book conveys the historical development of coordination chemistry via experiment sets
This guide includes experiments appropriate for college students at all levels, including graduate students. While they get a concise review of coordination chemistry, students also grasp the fundamentals of investigative techniques. An excellent lab manual, this is also ideal for students in bioinorganic chemistry and instrumental analysis. A complementary Instructor′s Manual helps instructors plan, develop, and customize courses.
1. Experimental Inorganic Chemistry: A History of Dazzling Color!
2. Levels 1 2. Werner s Notion Creating the Field: Synthesis and Analysis of Cobalt Ammine Coordination Compounds.
3. Levels 3 and 4. Molecular Geometry and Stability: Solid and Solution Phase Analysis of N,N′–disalicylaldehyde–1,3–propanediimine nickel(II).
4. Levels 3 4. Reactivity I: Substitution Reactions The Reaction of Aquapentacyanoferrate(II) Ion [Fe(CN)5(H2O)]3– with Amino Acids.
5. Levels 4 and 5. Electron Transfer Reactions Structure, Properties and Reactivity of Tris(bidentate chelate) cobalt(II/III) Complexes.
6. Levels 4 and 5. Metals in Medicine: Synthesis and Biological Reactivity of the Platinum Anticancer Drug, cis–Platin and its Isomer, trans–Platin.
7. Levels 4 and 5. Metals in the Environment Cd2+ Sequestration by Phytochelatins and Bioremediation.
8. Level 5. Metals in Molecular Biology Synthesis, Photophysical and Chiral Properties of Tris(1,10–Phenanthroline)Chromium(III): Metal Complex DNA Interactions and Reactivity.
9. Level 5. Oxidation of a Natural Product by a Vanadium Catalyst: Synthesis and Catalytic Activity of Vanadyl–bis (2,4–pentanedione), VO(acac)2.
Appendix 1. Introduction to Pulsed NMR Spectroscopy of Metal Complexes.
Appendix 2. Introduction to Cyclic Voltammetry.
Appendix 3. States and Term Symbols for Polyelectronic Systems.
Appendix 4. Setting up an Maintaining CHO Cell Culture.
Appendix 5. Setting Up and Maintaining Yeast Culture.
Appendix 6. A Brief Guide to Writing in Chemistry.
"Even coordination chemists who already know everything can benefit from this book as a source of inspiration...Not many textbooks can claim to have achieved that and to deserve the label "surprising"." (Angewandte Chemie International Edition, January 2008)