NMR of Proteins and Nucleic Acids. Baker Lecture Series

  • ID: 2175980
  • Book
  • 320 Pages
  • John Wiley and Sons Ltd
1 of 4
An introduction to underlying principles and experimental procedures using the newest strategies and techniques for obtaining extensive NMR assignments in biopolymers based on NMR data and the primary structure. Includes an extensive and non–mathematical discussion of 2D NMR and Nulcear Overhauser effects; resonance assignments and structure determination in proteins; and resonance assignments and structure determination in nucleic acids. Enables specialists and non–specialists to evaluate the potentialities and limitations of the method.
Note: Product cover images may vary from those shown
2 of 4
Introduction and Survey.

THE FOUNDATIONS: STRUCTURE AND NMR OF BIOPOLYMERS.

NMR of Amino Acid Residues and Mononucleotides.

NMR Spectra of Proteins and Nucleic Acids in Solution.

The NMR Assignment Problem in Biopolymers.

Two–Dimensional NMR With Proteins and Nucleic Acids.

Nuclear Overhauser Enhancement (NOE) in Biopolymers.

RESONANCE ASSIGNMENTS AND STRUCTURE DETERMINATION IN PROTEINS.

NOE–Observable 1H–1H Distances in Proteins.

Sequence–Specific Resonance Assignments in Proteins.

Polypeptide Secondary Structures in Proteins by NMR.

Three–Dimensional Protein Structures by NMR.

RESONANCE ASSIGNMENTS AND STRUCTURE DETERMINATION IN NUCLEIC ACIDS.

NOE–Observable 1H–1H Distances in Nucleic Acids.

Resonance Assignments in Nucleic Acids Using Scalar Couplings.

Nucleic Acid Conformation, 1H–1H Overhauser Effects, and Sequence–Specific Resonance Assignments.

WITH NMR TO BIOPOLYMER CONFORMATION AND BEYOND.

Conformation of Noncrystalline Proteins and Nucleic Acids.

NMR Studies of Intermolecular Interactions with Biopolymers.

References.

Index.
Note: Product cover images may vary from those shown
3 of 4

Loading
LOADING...

4 of 4
Kurt Wuthrich was a co–recipient of the 2003 Nobel Prize in Chemistry for his work on nuclear magnetic resonance technology and its application to protein analysis.
Note: Product cover images may vary from those shown
5 of 4
Note: Product cover images may vary from those shown
Adroll
adroll