An Introduction to Recombinant DNA in Medicine. 2nd Edition

  • ID: 2176057
  • Book
  • 216 Pages
  • John Wiley and Sons Ltd
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An extensively updated version of Alan Emery?s Introduction to Recombinant DNA, this new edition reflects the major advances in molecular genetics which have occurred in the last decade. Essentially it is a straightforward outline of the general principles and medical applications of molecular genetics which describes experimental techniques in a jargon–free style. Bibliographies and a glossary are provided, and this edition is extensively revised and illustrated with explanatory diagrams and photographs. With the emphasis on clinical applications rather than technology, and little biochemical knowledge assumed, this book is ideal for anyone approaching the subject of molecular genetics for the first time, whether from a clinical, medical or science background.

Reviews from First Edition:
?The book is extremely well written and immensely readable. It is clearly a classic that should be read by all practising clinicians.? Journal of the Royal Society of Medicine
?This book, written in a style that is easy to read, is an excellent first step for clinicians and any other scientists interested in molecular biology applied to medicine.? The Lancet

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The Development of Recombinant DNA Technology.

Structure and Function of DNA.

The Technology.

Gene Mapping, Structure and Function.

Molecular Pathology of Single Gene Disorders.

Molecular Pathology of Some Common Diseases.

Prevention of Genetic Disease.

Treatment.

Some Broader Applications.

Problems and Future of Recombinant DNA.

Glossary.

Index.
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Alan E. H. Emery, Emeritus Professor of Human Genetics, University of Edinburgh, Honorary Fellow, Green Templeton College, Oxford and Honorary Visiting Fellow, Peninsula College of Medicine, Plymouth, UK,Francesco Muntoni, Professor and Honorary Consultant in Paediatric Neurology, UCL Institute of Child Health and Great Ormond Street Hospital Foundation Trust, London, UK,Rosaline C. M. Quinlivan, Consultant in Neuromuscular Disorders, Centre for Neuromuscular Diseases, National Hospital for Neurology and Neurosurgery, and Dubowitz Neuromuscular Centre, Great Ormond Street Foundation Trust, London UK.

Alan EH Emery is a qualified physician, scientist and educator with wide experience of patient care and human genetics laboratory research. In 1966 he was first to describe a unique form of Emery–Dreifuss muscular dystrophy and to discover a significant biochemical defect linked to the pathogenesis of Duchenne muscular dystrophy. On this he wrote the first detailed scientific monograph in 1987 (Duchenne Muscular Dystrophy, Oxford University Press; 4th edition, 2014) and in 1989 founded the European Neuromuscular Centre to research related disorders. He has published over 400 scientific papers and written or edited 30 books regarding clinical, biochemical and genetic studies in neuromuscular disorders. For his work over the last 40 years he has received many national and international awards, including the Lifetime Achievement Award of the World Federation of Neurology. He is currently a Vice–President of the Muscular Dystrophy Campaign of Great Britain.

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