Preimplantation Genetic Diagnosis

  • ID: 2176279
  • Book
  • 278 Pages
  • John Wiley and Sons Ltd
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Preimplantation Genetic Diagnosis provides a valuable introduction and overview of the principles and practice of this relatively new branch of medicine, which has been formed by the fusion of Prenatal Diagnosis (PD) with in vitro fertilisation (IVF). This book contains research from leading scientists and clinicians within this field.

Features include:

∗ A concise introduction to the field of Preimplantation Genetic Diagnosis (PGD)

∗ Detailed explanations of the techniques and procedures used

∗ The law and ethical implications of PGD

∗ Future uses of PGD

Preimplantation Genetic Diagnosis has been carefully written for both the prenatal diagnosis community (clinical geneticists and fetal medicine specialists within obstetrics and gynaecology) and the IVF and reproductive medicine community, with special introductory chapters for non–specialists.
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List of Contributors.



Introduction (J. Harper).

Genetic Basis of Inherited Disease (J. Delhanty).

Prenatal Diagnosis (A. Cockell & C. Rodeck).

Genetic Counselling (S. Raeburn).

In Vitro Fertilization (K. Elder).

Gametogenesis and Preimplantation Embryo Development (K. Elder & S. Fleming).

Preimplantation Genetics (E. Pergament, et al.).


Clinical Aspects of Preimplantation Diagnosis (C. Overton, et al.).

Embryo Biopsy (J. Harper & A. Thornhill).

Diagnosis of Single Gene Disorders (D. Wells & J. Sherlock).

FISH and Embryo Sexing to Avoid X–linked Disease (J. Harper & L. Wilton).

Preimplantation Genetic Diagnosis of Chromosome Abnormalities: Specific Chromosomal Rearrangements and Age–related Aneuploidy (J. Delhanty & C. Conn).


Ethical Perspectives and Regulation of Preimplantation Genetic Diagnostic Practice (S. Viville, et al.).

Future Developments in PGD (J. Harper & D. Wells).

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Joyce C. Harper
Joy D. A. Delhanty
Alan H. Handyside
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