Foldamers. Structure, Properties and Applications

  • ID: 2179712
  • Book
  • 456 Pages
  • John Wiley and Sons Ltd
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This truly comprehensive treatise of foldamers, ranging from synthesis to applications in bio–,material, and nanoscience, is both an introduction to the topic, while also providing in depth accounts on various aspects aimed specifically at the specialist.

The book is clearly structures, with the firs part concentrating on structure and foldamer design concepts, while the second part covers functional aspects from properties to applications. The international team of expert authors provides up–to–date overviews of this rapidly expanding and highly interdisciplinary field.

From the foreword by Francios Diederich, Swiss Federal Institute of Technology (ETH), Zurich: "I strongly recommend this monograph to all academic and industrial researchers interest in fascinating perspectives for future chemical research; it will also take its place in modern graduate student education."

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Foreword

STRUCTURE: FOLDAMER DESIGN CONCEPTS

Foldamers Based on Local Conformation Preferences

Foldamers Based on Remote Intrastrand Interactions

Foldamers Based on Solvophobic Effects

Foldamer Hybrids: Defined Supramolecular Structures from Flexible Molecules

Control of Polypeptide Chain Folding and Assembly

Simulation of Folding Equilibria

FUNCTION: FROM PROPERTIES TO APPLICATIONS

Foldamer–based Molecular Recognition

Biological Application of Foldamers

Protein Design

Nucleic Acid Foldamers: Design, Engineering and Selection of Programmable Biomaterials with Recognition, Catalytic and Self–assembly Properties

Helically Folding Polymers

Polyisocyanides: Stiffened Foldamers

Foldamers at Interfaces

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Stefan Hecht
Ivan Huc
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