The Protein Chart

  • ID: 2179823
  • Book
  • 6 Pages
  • John Wiley and Sons Ltd
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What the Periodic Table did for the visualization of chemical concepts, this chart will achieve for structural biology. This truly innovative product addresses a growing need in the scientific community –– making the entire spectrum of protein structures instantly accessible on one handy chart. By way of a clever arrangement into rows and columns, this is much more than a simple field guide to individual protein structures: It is also an invaluable aid to understanding the principles behind protein structure diversity.

There is simply no better tool to introduce students to the secrets of proteins.
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INSIDE FACING

The main table displays 86 stuctural domains, organized into four major (alpha proteins, beta proteins, alpha/beta proteins, knots and fibers) and 26 minor architectural classes (such as sandwich, barrel, horseshoe, orthogonal bundle etc.).

For each domain, a representative structure is shown alongside structural and functional information for the fold group.

The abundance of each fold group in the currently sequenced more than 500 genomes is given, with the 10 most abundant "superfolds" highlighted.

OUTSIDE FACING

A satellite table of oligomeric proteins depicts 37 oligomer architectures, ordered according to their highest order rotation axis. For each class, a representative structure is displayed, along with structural and functional information on the class.

Also on the chart is a summary of 10 basic secondary structure topologies (shown in a 2D representation) and of the 12 most important three–dimensional structural motifs such as HTH, EF hand, HLH, Zn finger, P–loop, Greek key etc.

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Richard Charles Garratt
Christine A. Orengo
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