"An excellent text . . . will no doubt provide the benchmark for comparative works for many years." Journal of the American Chemical Society
"An excellent state–of–the–art compilation of catalytic asymmetric chemistry . . . should be included in any chemistry reference collection." Choice
"This is a tremendous resource and an excellent read. I recommend immediate purchase." Perkin Transactions
Since this important work was first published in 1993, the field of catalytic asymmetric synthesis has grown explosively, spawning effective new methods for obtaining enantiomerically pure compounds on a large scale and stimulating new applications in diverse fields from medicine to materials science. Catalytic Asymmetric Synthesis, Third Edition addresses these rapid changes through contributions from highly recognized world leaders in the field.
This seminal text presents detailed accounts of the most important catalytic asymmetric reactions known today, and discusses recent advances and essential information on the initial development of certain processes. An excellent working resource for academic researchers and industrial chemists alike, the Third Edition features:
Six entirely new chapters focusing on novel approaches to catalytic asymmetric synthesis including non–conventional media/conditions, organocatalysis, chiral Lewis and Bronsted acids, CH activation, carbon–heteroatom bond–forming reactions, and enzyme–catalyzed asymmetric synthesis
A new section focusing on the important new reaction, asymmetric metathesis, in carbon–carbon bond–forming reactions
Updated chapters on hydrogenation, carbon–carbon bond–forming reactions, hydrosilylations, carbonylations, oxidations, amplifications and autocatalysis, and polymerization reactions
Retaining the best of its predecessors but now thoroughly up to date, Catalytic Asymmetric Synthesis, Third Edition serves as an excellent desktop reference and text for researchers and students from the upper–level undergraduates through experienced professionals in industry or academia.
Preface to the Second Edition.
Preface to the First Edition.
1 Catalytic Asymmetric Synthesis in Non–Conventional Media/Conditions (Chikako Ogawa and Shu Kobayashi).
2 Asymmetric Organocatalysis.
2A Enantioselective Organocatalysis Involving Iminium, Enamine, SOMO and Photoredox Activation (Allan J. B. Watson and David W. C. MacMillan).
2B Asymmetric Acid–Base Bifunctional Catalysis with Organic Molecules (Yi Wang and Li Deng).
2C Asymmetric Phase–Transfer and Ion Pair Catalysis (Seiji Shirakawa and Keiji Maruoka).
3 Chiral Lewis Acids and Brønsted Acids in Asymmetric Synthesis (Hisashi Yamamoto and Cheol Hong Cheon).
4 Asymmetric Synthesis through C?H Activation (Huw M. L. Davies and Jørn Hansen).
5 Asymmetric Carbon–Heteroatom Bond–Forming Reactions (Yoshiji Takemoto and Hideto Miyabe).
6 Enzyme–Catalyzed Asymmetric Synthesis (Harald Gröger).
7 Transition Metal–Catalyzed Homogeneous Asymmetric Hydrogenation (Gao Shang, Wei Li and Xumu Zhang).
8 Asymmetric Carbon–Carbon Bond Forming Reactions.
8A Catalytic Asymmetric Conjugate Addition (Jian–Xin Ji and Albert S. C. Chan).
8B Enantioselective Allylic Substitutions with Carbon–Nucleophiles (Günter Helmchen,Uli Kazmaier and Sebastian Förster).
8C Asymmetric Carbometallation and Carbocyclizations (Iwao Ojima, Joseph J. Kaloko, Stephen J. Chaterpaul, Yu–Han Gary Teng and Chi–Feng Lin).
8D Asymmetric Ene Reactions and Cycloadditions (Koichi Mikami and Kohsuke Aikawa).
8E Catalytic Enantioselective Olefin Metathesis Reactions (Amir H. Hoveyda, Steven J. Malcolmson, Simon J. Meek and Adil R. Zhugralin).
9 Asymmetric Hydrosilation of Carbon–Carbon Double Bonds and Related Reactions (Jin Wook Han and Tamio Hayashi).
10 Asymmetric Carbonylations (Cyril Godard, Aurora Ruiz, Montserrat Diéguez, Oscar Pàmies and Carmen Claver).
11 Asymmetric Oxidations and Related Reactions (Kazuhiro Matsumoto and Tsutomu Katsuki).
12 Asymmetric Amplification and Autocatalysis (Kenso Soai, Tsuneomi Kawasaki, and Takanori Shibata).
13 Asymmetric Polymerization (Shingo Ito and Kyoko Nozaki).