Parasitology. An Integrated Approach

  • ID: 2180792
  • Book
  • 456 Pages
  • John Wiley and Sons Ltd
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Parasitology is a concise, student–friendly account of parasites and parasitic relationships with a strong emphasis throughout on parasite interactions with other pathogens as well as looking at how host behaviour contributes to the spread and control of infections.

The effects of parasitic infections are influenced by a range of host factors such as genetic constitution, immune status, and behaviour and this text takes an integrated approach to provide a full understanding of a wide range of topics from molecular biology and immunology to social, religious and cultural factors. Emphasis is also given to diagnostic techniques, from light microscopy to advanced molecular biology, and to treatment and control – highlighting recent advances in medicine, genomics and economics.
  • A concise, clearly–written integrated introduction to the study of parasites.
  • Includes self–assessment quizzes, case studies and suggestions for student projects.
  • Clearly set out with sections of full colour illustrations.
  • An emphasis on recent research throughout.
  • Companion website with additional illustrations, quizzes and project work.(URL to be added)

Students of biology, zoology, agriculture, animal welfare, biomedical sciences, medicine and veterinary science will appreciate this clear and accessible introduction.

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Preface xiii

1 Animal associations 1

1.1 Introduction 1

1.2 Animal associations 1

1.3 Parasite hosts 11

1.4 The co–evolution of parasites and their hosts 13

1.5 Parasitism as a ′lifestyle′: advantages and limitations 16

1.6 The economic cost of parasitic diseases 18

1.7 Why parasitic diseases remain a problem 21

1.8 Taxonomy 24

2 Parasitic protozoa, fungi and plants 28

2.1 Introduction 28

2.2 Parasitic protozoa 28

2.3 Phylum Rhizopoda 29

2.4 Phylum Metamonada 34

2.5 Phylum Apicomplexa 40

2.6 Subclass Coccidiasina 50

2.7 Phylum Kinetoplastida 62

2.8 Phylum Chlorophyta 81

2.9 Kingdom fungi 83

2.10 Kingdom plantae 85

3 Helminth parasites 86

3.1 Introduction: invertebrate taxonomy 86

3.2 Phylum Platyhelminthes 87

3.3 Class Trematoda 87

3.4 Class Cestoda 103

3.5 Phylum Acanthocephala 112

3.6 Phylum Nematoda (Nemata) 114

4 Arthropod parasites 137

4.1 Introduction 137

4.2 Phylum Chelicerata 138

4.3 Phylum Crustacea 148

4.4 Sub–phylum Hexapoda 153

5 Parasite transmission 180

5.1 Introduction 180

5.2 Contaminative transmission 181

5.3 Transmission associated with reproduction 184

5.4 Autoinfection 189

5.5 Nosocomial transmission 190

5.6 Active parasite transmission 191

5.7 Hosts and vectors 192

5.8 Host factors 196

5.9 Co–transmission and interactions between infectious agents 199

5.10 How religion can influence parasite transmission 202

5.11 The influence of war on parasite transmission 204

5.12 The influence of parasites on host behaviour 205

5.13 Environmental factors 207

6 Immune reactions to parasitic infections 212

6.1 Introduction 212

6.2 Invertebrate immunity 213

6.3 Vertebrate immunity 215

6.4 Innate immunity to parasitic infection 221

6.5 Adaptive immunity 226

6.6 Immunity to malaria 233

6.7 Schistosoma mansoni and Hepatitis C virus interactions 237

6.8 HIV–AIDS and parasitic disease 238

7 Pathology 245

7.1 Introduction 245

7.2 Factors that influence pathogenesis 245

7.3 Mechanisms by which parasites induce pathology 247

7.4 Types of pathology 250

7.5 Damage to specific organs 269

7.6 Co–infections and pathogenesis 289

8 The useful parasite 292

8.1 Introduction: the goodness of parasites? 292

8.2 The importance of parasites for the maintenance of a healthy immune system 293

8.3 The use of parasites to treat medical conditions 297

8.4 Parasites as sources of novel pharmaceutically–active compounds 308

8.5 Parasites as biological control agents 309

8.6 Parasites as forensic indicators 312

9 Identification of protozoan and helminth parasites 316

9.1 Introduction 316

9.2 The importance of correct identification 316

9.3 Properties of an ideal diagnostic test 318

9.4 Isolation of parasites 320

9.5 Identification from gross morphology 323

9.6 Biochemical techniques 329

9.7 Immunological techniques 329

9.8 Molecular techniques 331

9.9 Rapid diagnostic tests (RDTs) 334

9.10 MALDI–TOF MS 337

10 Parasite treatment and control 339

10.1 Introduction 339

10.2 Importance of understanding parasite life cycles for effective treatment and control 339

10.3 Treatment of parasitic diseases 341

10.4 Vaccines against parasitic diseases 356

10.5 Control of parasitic diseases 362

References 375

Index 431

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Overall, a very enjoyable and useful book at a price that is not too astronomical .   (British Journal of Biomedical Science, 1 January 2013)

Suitable as an undergraduate text in parasitology courses.  Summing Up:  Recommended.  Lower–and upper–division undergraduates.   (Choice, 1 January 2013)

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