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The Organic Chemistry of Drug Synthesis, Volume 1. Organic Chemistry Series of Drug Synthesis

  • ID: 2181242
  • Book
  • February 1977
  • 496 Pages
  • John Wiley and Sons Ltd
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Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.
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A Case Study in Molecular Manipulation: The Local Anesthetics.

Monocyclic Alicyclic Compounds.

Benzyl and Benzhydryl Derivatives.

Penethyl and Phenylpropylamines.

Arylacetic and Arylpropionic Acids.

Arylethylenes and Their Reduction Products.

Monocyclic Aromatic Compounds.

Polycyclic Aromatic Compounds.



Acyclic Compounds.

Five–Membered Heterocycles.

Six–Membered Heterocycles.

Derivatives of Morphine, Morphinan, and Benzomorphan;


Five–Membered Heterocycles Fused to One Benzene Ring.

Six–Membered Heterocycles Fused to One Benzene Ring.



Additional Heterocycles Fused to Two Benzene Rings.

beta–Lactam Antibiotics.

Miscellaneous Fused Heterocycles.

Cross Index of Drugs.


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Daniel Lednicer
Lester A. Mitscher
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