Industrial Biotechnology. Sustainable Growth and Economic Success

  • ID: 2183097
  • Book
  • 522 Pages
  • John Wiley and Sons Ltd
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Industrial Biotechnology, also referred to as "White Biotechnology", is a green and clean technology based on renewable resources, with promising increased conversion efficiency and specificity, less waste generation, lower energy consumption and reduced greenhouse gas emission.

Describing most of the topics on white biotechnology admitted to the 7th EU Framework Program as well as new industrial production processes aiming towards reaching the Kyoto objectives, this comprehensive textbook covers the enabling sciences and technologies, the application domains, as well as the economic potential and societal impact.

From the contents:

∗ History of industrial biotechnology

∗ Use of renewable versus fossil resources

∗ Systems microbial biotechnology

∗ Metabolic engineering and modeling

∗ Fermentation technologies

∗ Directed evolution and production of of industrial enzymes

∗ Nanobiotechnology

∗ Downstreamprocessing

∗ Chemicals and biopharmaceuticals

∗ Food and feed

∗ Paper and pulp

∗ Fuels from biomass

∗ Enviromental, economic and societal aspects

This comprehensive text is primarily directed at readers with a general interest in Industrial Biotechnology. It is equally very suitable as an introductory handbook to students , scientists and academics as well as researchers and engineers now active in a wide range of industries, including the bulk, fine and petrochemical sector, biotechnology and pharmaceutical companies, the personal care sector, the food and feed industries, agriculture and biorefineries, the paper and pulp sector, energy and fuel production and many more.
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Preface

THE SCOPE AND IMPACT OF INDUSTRIAL BIOTECHNOLOGY

HISTORY OF INDUSTRIAL BIOTECHNOLOGY

Early History

The Penicillin Story

The Coming of the Cephalosporins

The Waksman Era

Strain Improvement

Semi–Synthetic Antibiotics to Combat Resistant Microbes

The Primary Metabolites

The Shift from Antibiotics to Pharmacological Agents

The Biopharmaceutical Revolution

Recombinant Hosts

Enzymes

Bioconversions

Vaccines

Systems Microbiology

INDUSTRIAL SYSTEMS BIOLOGY

Introduction

Industrial Biotechnology

Market Drivers for Industrial Biotechnology

Industrial Systems Biology

Metabolic Models

Reconstructed Metabolic Network Models

Industrial Systems Biology Case Studies

Conclusion and Future Perspectives

FERMENTATION TECHNOLOGY

Introduction

Types of Fermentations

Fermentation Process

Fermentation Medium Design

sterilization of Air and Fermentation Medium

Environmental Factors

Fermentation Kinetics

Fermentation Equipment

Recovery of Fermentation Products

Concluding Remarks

DIRECTED EVOLUTION OF INDUSTRIAL BIOCATALYSTS

Introduction

Strategies for Protein Design

Assay Systems

Examples

Conclusions

THE INDUSTRIAL PRODUCTION OF ENZYMES

Introduction

Enzyme Production

Enzyme Improvement

Large–Scale Enzyme Applications

Conclusions

APPLIED BIOCATALYSIS: AN OVERVIEW

Introduction

The Design of the Bioconversion System

Bioreactors

Rationalizing and Speeding Up the Development and Characterization of a Bioconversion Process

Concluding Remarks

NANOBIOTECHNOLOGY

Setting the Stage

Industrial Perspective

Nanotechnology in Biology and Biochemistry

Biomimicry

Materials and Products

Processes and Devices

Outlook

DOWNSTREAM PROCESSING IN INDUSTRIAL BIOTECHNOLOGY

Introduction

Separations in Industrial Biotechnology

Examples of Downstream Processing of Different Product Groups

INDUSTRIAL BIOTECHNOLOGY IN THE CHEMICAL AND PHARMACEUTICAL INDUSTRIES

Introduction

Biocatalytic Processes: Scientific and Technological Perspectives

Biocatalytic Processes: Business and Commercial Perspective

Safety, Health, and the Environmental Perspective

Outlook

INDUSTRIAL BIOTECHNOLOGY IN THE FOOD AND FEED SECTOR

Introduction

Food Applications

Food and Feed Applications

Feed Applications

INDUSTRIAL BIOTECHNOLOGY IN THE PAPER AND PULP SECTOR

Introduction

Enzymes for the Pulp and Paper Industry

Enzymes as Process Aids

Enzymes for Product Design

Biorefinery Concepts

Conclusions

BIOFUELS: PRODUCTION AND APPLICATIONS

A Renewed Interest in Biofuels

Present Conversion Pathways

Biodiesel Production from Vegetable Oils and Fats

Ethanol and ETBE Production

The Need for New Developments

Lignocellulosic Biomass Resources

Production of Ethanol from Lignocellulosic Biomass

Production of Biofuels Through the Thermochemical Pathway

Biorefineries

Biofuels and Sustainability

Conclusion

ENVIRONMENTAL AND ECONOMIC ASPECTS OF INDUSTRIAL BIOTECHNOLOGY

Introduction

Methodology

Overall Results

Conclusions

SOCIETAL ISSUES IN INDUSTRIAL BIOTECHNOLOGY

Introduction

The Impact of Industrial Biotechnology

Public Perceptions of Industrial Biotechnology

Societal Issues in Industrial Biotechnology

Conclusions and Discussions: A Joint Agenda for the Smooth Introduction of Acceptable Sustainable Industrial Biotechnology

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Wim Soetaert
Erick J. Vandamme
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