Stress - From Molecules to Behavior. A Comprehensive Analysis of the Neurobiology of Stress Responses

  • ID: 2183268
  • Book
  • 395 Pages
  • John Wiley and Sons Ltd
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This title comprehensively covers the molecular basis of stress responses of the nervous system, providing a unique and fundamental insight into the molecular, physiological and behavioral basis of the stress response of a whole organism. Edited by leading experts in the field and summarizing the latest research advances in this area, this ready reference is an invaluable resource for clinicians dealing with stress–related disorders, biomedical researchers working in the field as well as for pharmacology and biotech companies.
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SYSTEMS

On the Role of Stress in Evolution (Hadany)

Catecholamines and Stress (Sabban)

Stress and the Cholinergic System: (De Biasi)

CELLS AND CIRCUITS

Effects of Stress on the Function of Hippocampal Cells (Joëls, Karst)

Stress and Adult Neurogenesis in the Mammalian Central Nervous System (Kirby, Kaufer)

Individual differences in Reactivity to Social Stress in the Laboratory and its Mediation by Common genetic polymorphisms (Shalev, Lerer, Israel, Uzefovsky, Gritsenko, Mankuta, Kait, Ebstein)

COGNITION AND BEHAVIOUR

Corticosteroid Hormones in Stress and Anxiety;

Role of Receptor Variants and Environmental Inputs (de Rijk, Kitraki, de Kloet)

Corticotropin–Releasing Factor (CRF) and CRF–Related Peptides– a Linkage Between Stress and Anxiety (Thomas Blank, Joachim Spiess)

Stress, Emotion, and Memory: The Good, the Bad, and the Intriguing (Marin, Schramek, Maheu, Lupien)

Contribution of Early Life Stress to Anxiety Disorder (Weinstock)

IMMUNE RESPONSES

Stress Effects on Immunity in vertebrates and Invertebrates (Shapira)

Immunity to Self Maintains Resistance to Mental Stress;

Boosting Immunity as a complement to Psychological Therapy (Lewitus, Schwartz–Stav, Schwartz)

Brain Interleukin–1 (IL–1) Mediates Stress–Induced Alterations in HPA Activation, Memory Functioning and Neural Plasticity (Goshen, Yirmiya)

POST–TRAUMATIC STRESS DISORDER

Post–Traumatic Stress disorder in Animal Models (Cohen, Kozlovsky, Richter–Levin, Zohar)

The Cholinergic Model for PTSD: From Acute Stress to PTSD, From Neuron to Network and Behavior: (Friedman, Pavlovsky)

VULNERABILITY TO DISEASE

Stress and Neurodegeneration: Adding Insult to Injury? (Berson, Hanan, Soreq)

Stress and Neurotransmission: Clinical Evidence and Therapeutic Implications (Shalev, Cohen)

Metabolic Components of Neuroendocrine Allostatic Responses: Implications in Life–Style Related Diseases (Berg, Pedersen)

Environmental Stress is not Always Vicious: A Lesson from Heat Acclimation–Mediated Neuroprotection after Traumatic Brain Injury (Horowitz and Shohami)

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Hermona Soreq, PhD, professor of molecular biology and the elected Dean at the Faculty of Mathematics and Natural Sciences, The Hebrew University of Jerusalem is best known for her discovery of the molecular basis of mammalian stress reactions which increase the risk of chronic diseases such as anxiety and fear responses, muscle fatigue, inflammation and neurodegeneration. This, and the development of RNA–targeted oligonucleotide drugs limiting accumulation of stress–induced proteins, are fundamentally important at both neuroscience and genomic research levels. Prof. Soreq has authored over 400 scientific publications and has been awarded several prizes and honorary degrees at Stockholm, Buenos–Aires, Erlangen–Nuremberg and Beer–Sheva.

Daniela Kaufer earned a PhD from the Hebrew University of Jerusalem and completed post–doctoral training at Stanford University. She is an assistant professor in the Department of Integrative Biology at UC Berkley, and associated with the Helen Wills Neuroscience Institute, and the Berkeley Stem Cell Center. Current research in her lab focuses on hormonal regulation of adult hippocampal neurogenesis, and the regulation of gene expression and RNA processing (i.e., transcription regulation, RNA splicing and micro RNA) under stress, blood brain barrier injury and neurological insults. In her work Dr. Kaufer combines genomics, cellular and molecular imaging techniques, with physiological and behavioral tools.

Alon Friedman graduated from Ben–Gurion University of the Negev in 1992 after completing its MD–PhD program. He leads the laboratory for neurophysiology and experimental neurosurgery in Ben–Gurion University and Soroka University Medical Center. His research focuses on the pathophysiology of brain disorders, specifically on the effects of stress on the function of the neurovascular unit and the role of the blood–brain barrier in the pathophysiology of brain disorders. In his work Dr. Friedman combines clinical and basic research using molecular, imaging and neurophysiological approaches in both human patients and animal models.
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