- Includes a considerations of the epidemiology of brain metastases and the quality of life in patients who have them.
- Special topics not previously covered are reviewed, including metastasis to the skull base and strategies for preventing cancer from metastasizing to the brain.
- A novel feature is a chapter devoted to the use of recent techniques such as functional magnetic resonance (MR) imaging, MR spectroscopy (metabolite mapping), and dynamic susceptibility contrast imaging (regional cerebral blood volume mapping) to characterize brain metastases in terms of the sensorimotor perturbations they produce, their metabolic response to therapy, and their degree of vascularization, respectively.
1 Management of Intracranial Metastases: History.
Deric Minwoo Park, MD and Jerome B. Posner, MD.
2 The Epidemiology of Brain Metastasis.
Dima Suki, PhD.
3 The Biology of Brain Metastasis.
Isaiah J. Fidler, DVM, PhD.
4 Brain Metastases: Histopathologic Evaluation and Diagnostic Pitfalls.
Teresa Ribalta, MD, PhD and Gregory N. Fuller, MD, PhD.
5 Imaging of Metastatic Tumors of the Brain.
Norman E. Leeds, MD, Edward F. Jackson, PhD, MS, BS, and Ashok J. Kumar, MD.
II. Principles of Therapy.
6 Intracranial Metastases: Medical Management and Prognostic Factors.
Susanne M. Arnold, MD and Roy A. Patchell, MD.
7 Surgical Management and Techniques.
Frederick F. Lang, MD, FACS.
8 Whole Brain Radiation Therapy.
Ritsuko Komaki, MD, FACR and Eric Chang, MD.
9 Radiosurgery for Single and Multiple Brain Metastases.
Minesh P. Mehta, MD and Ivo Tremont–Lukats, MD.
10 Stereotactic Radiation of Intracranial Metastases.
Griffith R. Harsh IV, MD.
11 Chemotherapy for Brain Metastases.
Sigmund H. Hsu, MD and W. K. Alfred Yung, MD.
III. Specific Tumor Sites.
12 Metastatic Lung Cancer.
James L. Frazier, ScB, Ira M. Garonzik, MD, and Laurence D. Rhines, MD.
13 Current Management Strategies in Intracranial Breast Cancer Metastasis.
Stacy Moulder, MD, David H. Johnson, MD and Steven A. Toms, MD, MPH.
14 Management of Brain Metastasis in Malignant Melanoma Patients.
Andrew A. Kanner, MD and Gene H. Barnett, MD.
15 Brain Metastases from Renal Cell Carcinoma.
Fadi Hanbali, MD and Jeffrey S. Weinberg, MD.
16 Metastatic Colorectal Carcinoma.
Vijayabalan Balasingam MD, PhD, FRCS (C) and Ian E. McCutcheon MD, FRCS (C).
17 Brain Metastasis from Cancer of an Unknown Primary Site.
Robert J. Bohinski, MD, PhD and Ronald E. Warnick, MD.
18 Leptomeningeal Carcinomatosis: Diagnosis and Management.
Morris D. Groves, Jr., MD, JD.
19 Brain Metastases from Gynecologic Cancers.
Maciej S. Lesniak, MD and Alessandro Olivi, MD.
20 Brain Metastases from Genitourinary Cancer: Germ Cell, Testicular, Prostate and Bladder Cancer.
Philip V. Theodosopoulos, MD, James L. Rubenstein, MD, and Michael W. McDermott, MD.
21 Brain Metastasis from Upper Gastrointestinal Tract Cancers: Esophageal, Gastric, Hepatic, Gallbladder, and Pancreatic.
Jeffrey S. Weinberg, MD, Renato Lenzi, MD, and Ziya L. Gokaslan, MD, FACS.
22 Brain Metastases From Thyroid Carcinoma and Other Endocrine Malignancies.
Rena Vassilopoulou–Sellin, MD.
23 Brain Metastasis From Sarcomas.
Andrew E. Sloan, MD and Michael Kraut, MD.
IV. Special Considerations.
24 Metastatic Tumors of the Skull Base.
Fadi Hanbali MD and Franco DeMonte MD, FRCSC, FACS.
25 Neuropsychological Impact of the Brain Metastasis and its Treatment.
Anne E. Kayl, PhD and Christina A. Meyers, PhD, ABPP.
26 Adjuvant Approaches for Preventing Brain Metastases.
David G. Menter, PhD, Anita L. Sabichi, MD, and Scott M. Lippman, MD.
27 Intracranial Metastases: Management Guidelines and Decision Making.
Syed Enam, MD and Jack P. Rock, MD.