This is also the most up–to–date text in the field – The editors have referenced work up to October 2005, whilst still including all the classic research material and images where appropriate.
Essential for gynecologists, oncologists, basic scientists especially those involved in HPV (viral)research, GPs, nurses, colposcopy practitioners, and sexual transmitted disease doctors
The only definitive major clinical reference book published on the cervix for thirty years
Including the most up–to–date research on HPV including up–to–date vaccine trial data
Highly illustrated in colour including many surgical procedures
Spanning the entire field from embryology to cancer to emotional trauma
International editorship, with leading names in the field
Cervical cancer is the second biggest cause of female cancer mortality worldwide and therefore relevant to the developing and developed world
Specific chapters related to management of cervical cancer in the developing world
Summaries of recommendations by international bodies including the IARC conference (Lyon 2004), dealing with cervical cancer diagnosis and treatment
The Editors, Jordan and Singer, are the co–founders of the British Society for Colposcopy and Cervical Pathology
This edition has been radically transformed because of the discovery of the human papilloma virus and its crucial role in cervical cancer since the first edition was published. It also covers the very recent discovery of the vaccine against HPV. It contains a number of new chapters;
Decidual ectopy of the uterine cervix
Immunochemistry and immunology of the cervix
Angiogenesis in cervical neoplasia
Cytology of normal and neoplastic cervical epithelium
Cytological screening for cervical neoplasia
The management of multi–focal precancer of the lower genital tract
Radiotherapy in the treatement of cervical cancer
The management of cervical cancer by radiotherapy and chemotherapy
Vaccines to prevent and treat HPV associated disease
1 Morphogenesis and differentiation of the cervicovaginal epithelium.
John M. McLean.
2 The functional anatomy of the cervix, the cervical epithelium and the stroma.
Albert Singer and Joseph A. Jordan.
3 The vascular, neural and lymphatic anatomy of the cervix.
Timothy A.J. Mould and Carl Chow.
4 Immunochemistry and immunology of the cervix.
Margaret A. Stanley.
Part 2 Physiological and drug–induced alterations within the cervical epithelium.
5 Morphology of the fetal and prepubertal cervicovaginal epithelium.
The late Ellis Pixley and Albert Singer.
6 The cervical epithelium during puberty and adolescence.
Anna–Barbara Moscicki and Albert Singer.
7 The cervical epithelium and subepithelium during pregnancy and the puerperium.
8 Decidual ectopy of the uterine cervix.
9 The effects of oral contraceptive steroids, menopause and hormone replacement therapy on the cervical epithelium.
Sun Kuie Tay and Albert Singer.
10 Diethylstilbestrol (DES) and the cervicovaginal epithelium.
J. Michael Emens.
Part 3 The cervix and fertility and infertility.
11 The structure, chemistry and physics of human cervical mucus.
Khaldoun Sharif and Olufemi Olufowobi.
12 Sperm transport in the human and mammalian cervix and genital tract: its relation to fertility.
Anne M. Jequier.
Part 4 The cervix in pregnancy and labour.
13 Mechanics, biochemistry and pharmacology of the cervix and labour.
14 The incompetent cervix.
Roy G. Farquharson.
Part 5 Cervical infections.
15 Pathology of inflammatory diseases of the cervix.
Kasturi Das, Michele Burday and Debra S. Heller.
16 Common non–viral infections of the cervix: clinical features and management.
17 Common viral infections of the cervix (excluding human papillomavirus): clinical features and management.
Raymond H. Kaufman and Ervin Adam.
Part 6A Cervical neoplasia: natural history and pathology.
18 Epidemiology and the role of human papillomaviruses.
Anita Koushik and Eduardo L.F. Franco.
19 Molecular basis of cervical neoplasia.
Frank Stubenrauch and Thomas Iftner.
20 Angiogenesis in cervical neoplasia.
Peter W. Hewett and Asif Ahmed.
21 Pathology of neoplastic squamous lesions.
Raji Ganesan and Terence P. Rollason.
22 The pathology of glandular cervical lesions.
Raji Ganesan, the late Andrew G. Östör and Terence P. Rollason.
Part 6B Cervical neoplasia: screening.
23 Emotional aspects of cervical neoplasia screening and management.
Theresa Freeman–Wang and Amali Lokugamage.
24 Cytology of normal and neoplastic cervical epithelium.
Alastair R.S. Deery.
25 Cytological screening for cervical neoplasia.
26 Screening for cervical cancer using HPV tests.
Andrea R. Spence and Eduardo L.F. Franco.
27 Real–time devices for the screening and diagnosis of cervical neoplasia.
Karen Canfell and Carl Chow.
28A Tumour markers in cervical cancer – I.
John J. O Leary, Katharine Astbury and Walter Prendiville.
28B Tumour markers in cervical cancer – II.
Michael Sindos and Narendra Pisal.
29A Screening for cervical cancer in developing countries.
29B Visual screening for cervical neoplasia in developing countries.
Rengaswamy Sankaranarayanan, Thara Somanathan and Twalib Ngoma.
Part 6C Cervical neoplasia: management of premalignant and malignant disease.
Joseph A. Jordan and Albert Singer.
31 The management of cervical intraepithelial neoplasia (squamous).
Mahmood I. Shafi, Joseph A. Jordan and Albert Singer.
32 The management of cervical intraepithelial neoplasia (glandular).
David M. Luesley and Richard W. Todd.
33 The role of HPV in the management of cervical neoplasia.
Chris J.L.M. Meijer, Peter J.F. Snijders and René H.M. Verheijen.
34 The management of cervical premalignancy and malignancy in pregnancy.
Theresa Freeman–Wang and Patrick G. Walker.
35A Immunosuppression and the cervix: human immunovirus (HIV).
Thomas C. Wright Jr.
35B Immunosuppression and the cervix: other immunosuppressive disorders.
Adeola Olaitan and Theresa Freeman–Wang.
36 Staging and pretreatment evaluation of women with cervical cancer.
Howard W. Jones III.
37 The management of microinvasive carcinoma of the cervix.
Donald E. Marsden, Neville F. Hacker and Lyndal Edwards.
38 Management of early–stage cervical cancer by surgery.
John H. Shepherd.
39 The surgical techniques employed for treating early–stage cervical cancer.
Joseph Hanoch and G. Angus McIndoe.
40 The management of advanced cervical cancer by surgery.
John M. Monaghan.
41 The management of multifocal precancer of the lower genital tract.
Nigel Acheson and Richard W. Todd.
42 Radiotherapy in the treatment of cervical cancer.
43 Management of cervical cancer by radiotherapy and chemotherapy.
H. Margot L. Lehman and Gillian M. Thomas.
44 Vaccines to prevent and treat human papillomavirus associated anogenital disease.
Ian H. Frazer and Sally Appleton.
45 Psychosocial aspects associated with cervical disease and neoplasia.
Cornelius O. Granai.
46 Colposcopy training and accreditation.
Charles W.E. Redman.
47 The future – towards the elimination of cervical cancer.
Henry C. Kitchener.