For each condition, the authors give helpful advice on differential diagnoses and clinical management. This third edition has been extensively updated throughout, in light of recent developments in this rapidly advancing area of medicine.
A well established textbook on the diagnosis and treatment of blood disorders in childhood
∗ A balanced and a cutting edge referenced text on all aspects of diagnosis and treatment
∗ Easy to use – practically organised – with essential aspects of biology included within each chapter
∗ International editorial and contributor team representing a wide geographical and chronological range
Whether you are an established sub–specialist in pediatric hematology/oncology, a pediatrician, a trainee or nursing specialist this book will answer all your questions about benign and malignant disorders of the blood in children and young adults.
1 Hematopoiesis: an introduction (Hugh J.M. Brady).
Section 2: Marrow Failure Syndromes.
2 Failure of red cell production (Sarah E. Ball).
3 Inherited bone marrow failure syndromes (Yigal Dror).
4 Acquired aplastic anemia (Juliana Teo and Yigal Dror).
Section 3: Red Cell Disorders.
5 Disorders of iron metabolism: iron deficiency, iron overload and the sideroblastic anemias (Andrew M. Will).
6 Megaloblastic anemia and disorders of cobalamin and folate metabolism (Eric J. Werner).
7 Nonimmune neonatal anemias (Brenda E.S. Gibson and Christina Halsey).
8 Immune hemolytic anemias (Bertil Glader).
9 Disorders of erythrocyte metabolism including porphyria (Lawrence Wolfe and Peter E. Manley).
10 Sickle cell disease (Corrina McMahon).
11 Hemoglobin variants and the rarer hemoglobin disorders (Andreas E. Kulozik).
12 Red cell membrane abnormalities (Patrick G. Gallagher).
13 Thalassemias (Nancy F. Olivieri and David J. Weatherall).
Section 4: Granulocyte Disorders.
14 Disorders of granulopoiesis and granulocyte function (Arian Laurence, Pratima Chowdary and Philip Ancliff).
15 Histiocytic disorders (Amir H. Shahlaee and Robert J. Arceci).
16 Acute myeloid leukemia (Leslie S. Kean, Robert J. Arceci and William G. Woods).
17 Chronic myeloid leukemia (Irene A.G. Roberts and Inderjeet S. Dokal).
18 Myelodysplastic syndromes (David K.H. Webb).
Section 5: Lymphocyte Disorders.
19 Primary and acquired immunodeficiency (Andrew R. Gennery, Adam H.R. Finn and Andrew J. Cant).
20 Clinical features and therapy of lymphoblastic leukemia (Owen P. Smith and Ian M. Hann).
21 Lymphomas (O.B. Eden and Ross Pinkerton).
Section 6: Platelet Disorders.
22 Inherited and congenital thrombocytopenia (Owen P. Smith).
23 Idiopathic thrombocytopenic purpura (Paul Imbach).
24 Thrombocytosis (Christof Dame).
25 Platelet function disorders (Alan D. Michelson).
Section 7: Coagulation Disorders.
26 Hemophilia A and B (Judith Smith and Owen P. Smith).
27 von Willebrand disease (David Lillicrap).
28 Rare congenital hemorrhagic disorders (Nigel S. Key and Margaret A. Heisel–Kurth).
29 Acquired disorders of hemostasis (Elizabeth A. Chalmers, Michael D. Williams and Angela Thomas).
30 Bleeding in the neonate (Elizabeth A. Chalmers).
31 Thromboembolic complications in children (Mary Bauman and M. Patricia Massicotte).
Section 8: Supportive Therapy.
32 Blood components and fractionated plasma products: preparation, indications and administration (Nancy Robitaille and Heather A. Hume).
33 Hazards of transfusion (Naomi L.C. Luban and Edward C.C. Wong).
34 Management of infection in children with bone marrow failure (Subarna Chakravorty and Ian M. Hann).
Section 9: Secondary Problems.
35 Hematologic effects of systemic disease and nonhematopoietic tumors (Angela Thomas)
36 Lysosomal storage disorders (Brad T. Tinkle and Gregory A. Grabowski).
37 Reference values (Paula S. Simpkin and Roderick F. Hinchliffe).