Multiple Sclerosis. Diagnosis and Therapy

  • ID: 2223460
  • Book
  • 328 Pages
  • John Wiley and Sons Ltd
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Multiple Sclerosis: a complex disease requiring sophisticated management
Multiple Sclerosis poses labyrinthine challenges. There is no blood test to rely on for diagnosis; clinical acumen is essential. Yet an effective diagnosis only takes you part of the way: treatment offers further enigmas. The MS treatment landscape is complicated, and will become even more so with time.

Multiple Sclerosis: Diagnosis and Therapy is the map you need to navigate this maze. Written and edited by leaders in the field, it guides you towards effective and positive choices for your patients. The diagnosis section provides state–of–the–art thinking about pathogenesis. With clear coverage of biomarkers, genetics, and imaging, it presents a coherent framework for making the correct diagnosis. The management section comprehensively covers current and future treatments to steer you through the many options for

 Symptom management
 Cognitive dysfunction
 Depression and other mental health issues  

Top Tips throughout provide the practical guidance you need for the best management of your patients.

Multiple Sclerosis: Diagnosis and Therapy should be on the bookshelf of anyone who treats patients with multiple sclerosis.

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List of Contributors, vii

Preface, ix

Part I Pathology and Diagnosis, 1

1 Disease Pathogenesis, 3Roopali Gandhi and Howard L. Weiner

2 Biomarkers, 26Manuel Comabella and Samia J. Khoury

3 Epidemiology and Genetics, 56Philip L. De Jager

4 Diagnosis, 77James M. Stankiewicz, Varun Chaubal, and Guy J. Buckle

5 Pediatric Multiple Sclerosis and Acute Disseminated Encephalomyelitis, 101Tanuja Chitnis

6 Magnetic Resonance Imaging in Multiple Sclerosis, 136Mohit Neema, Antonia Ceccarelli, Jonathan S. Jackson, and Rohit Bakshi

7 Predicting Clinical Course, 163Brian Healy and Maria Liguori

Part II Management, 181

8 Medication Treatment in Multiple Sclerosis, 183James M. Stankiewicz and Samia J. Khoury

9 Symptom Management, 213Lynn Stazzone and Brandon Brown

10 Cognitive Dysfunction in Multiple Sclerosis, 239Bonnie I. Glanz and Maria K. Houtchens

11 Depression and Other Psychosocial Issues in Multiple Sclerosis, 263David J. Rintell

12 Future Therapeutic Approaches, 283Howard L. Weiner and Laura Edwards

Index, 301

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Edited byHoward L. Weiner, MD, Harvard Medical School, Brigham and Women′s Hospital & Partners MS Center, Boston, MA, USA

James M. Stankiewicz, MD,  Harvard Medical School, Brigham and Women s Hospital & Partners MS Center, Boston, MA, USA

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