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Natural Product Biosynthesis by Microorganisms and Plants Part B, Vol 516. Methods in Enzymology

  • ID: 2237546
  • Book
  • 462 Pages
  • Elsevier Science and Technology
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This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants.

- This new volume continues the legacy of this premier serial- Contains quality chapters authored by leaders in the field- The second of 3 volumes it has chapters on such topics as biological chlorination, bromination and iodination, and phylogenetic approaches to natural product structure prediction

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- In vivo production of thiopeptide variants- Microviridin biosynthesis- Cyclotide isolation and characterization- Ribosomally-encoded cyclic peptide toxins from mushrooms- The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: novel function for a non-ribosomal peptide synthetase- Discovery and biosynthesis of phosphonate and phosphinate natural products- RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins - Fe(II)-dependent, uridine-5'-monophosphate ?-ketoglutarate dioxygenases in the synthesis of 5'-modified nucleosides- Heme-dependent Tailoring Enzymes in Natural Product Biosynthesis: Spectroscopic Characterisation of the L-tryptophan-nitrating Cytochrome P450 TxtE- Oxidative Tailoring Reactions Catalysed by Non-heme Iron-dependent Enzymes: Streptorubin B Biosynthesis as an Example- The rare fluorinated natural products and biotechnological prospects for fluorine enzymology- Enzymatic chlorination and bromination- Prenyltransferases of the dimethylallyltryptophan synthase superfamily- Serine carboxypeptidase-like acyltransferases from plants- 4-Methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis- Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis- High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer
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