Therapeutic Applications and Strategies
SUNIL MAULIK and SALIL D. PATEL
Recombinant DNA technology, or genetic engineering, has revolutionized our understanding of life at the molecular level–giving us a detailed picture of the living cell′s functions and spawning diverse biotechnologies that use molecules, cells, tissues, and even entire organisms.
This introduction to molecular biotechnology is a practical, up–to–date guide to this rapidly growing field. Based on courses taught by the authors to biotechnology professionals, Molecular Biotechnology: Therapeutic Applications and Strategies applies the principles of modern biotechnology to advances and trends in the development of therapeutic strategies and approaches to disease prevention and intervention. By focusing on select applications and strategies, this volume exemplifies the convergence of biological, chemical, and informational advances in the discovery of novel targets and drugs. This multidisciplinary approach, essential to the development of commercial therapeutic molecules, includes carefully selected real–world examples from the pharmaceutical and biotechnology industries. Specific topics covered include:
∗ Genome Based Medicine and the Human Genome Project
∗ Human Gene Therapy
∗ Combinatorial Chemistry
∗ Rational Drug Design
∗ Reengineering the Immune System
User–friendly and organized for maximum understanding, Molecular Biotechnology: Therapeutic Applications and Strategies is an excellent text/reference for biotechnology professionals, researchers, physicians, students, managers, industry analysts, and investors interested in learning more about the field of molecular biotechnology.
Human Gene Therapy.
Drug Discovery by Combinatorial Chemistry and Molecular Diversity.
Protein Engineering and Computer–Assisted Drug Design.
Re–Engineering the Immune Response.