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Evidence-based Dementia Practice

  • ID: 2249627
  • Book
  • March 2002
  • Region: Global
  • 928 Pages
  • John Wiley and Sons Ltd
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The era of therapeutic nihilism in dementia has ended, with the emergence of agents for symptomatic treatment, those that delay the course of the disease or prevent the onset of dementia, and new methods to manage symptoms. With the expansion of therapies, there is a clear danger of being overwhelmed by the volume of data.

This book is designed to collect this information, distil what is relevant and reliable, and present it in a format that is useful to clinicians who manage and treat people with dementia. It brings together the latest and best evidence on all aspects of the disease and its management, from diagnosis and therapy to social and ethical considerations.

There are no other books that take such a practical and problem–oriented or approach to the diagnosis and management of dementia. Furthermore none but this can be described as being truely evidence–based.

The editors are all dynamic clinicians involved in the care of patients with dementia and the evaluation of therapies. Two of the editors are the leaders of the Cochrane Collaboration for the examination of therapies for dementia.

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SECTION I : Evidence–based Methods in Dementia.


Finding the evidence.

Critical Appraisal.

Evidence–based Etiology and Harm.

Evidence–based Diagnosis.

Evidence–based Prognosis.

Evidence–based Interventions.

Evidence–based Systematic Reviews and Meta–analyses.

Evidence–based Guidelines.

Evidence–based Economic Evaluation.

Accessing and Using the Best Evidence Efficiently in Dementia.

Evidence–based Audit: Evaluating Implementation.

SECTION II : Diagnosis.

Introduction Practice Guidelines.

Reaching a Diagnosis of Dementia.

Reaching a Diagnosis of Dementia Subtype Conclusions.

SECTION III : Background Facts.

Historical Evolution of the Concept of Dementia: a Systematic Review From 2000 BC to 2000 AD.

Alzheimer′s Disease.

Vascular Dementia.

Lewy Body Dementia.

Frontotemporal Lobar Atrophies: The Pick Complex.

Other Important Dementias.

Reversible or Arrestable Dementias.

Mild Cognitive Impairment.

SECTION IV: Overview of Treatment and Management.

Aims of Treatment.

Criteria for Clinical Decisions.

Clinical Decisions in Practice.

Delivering an Integrated Treatment Plan.

What is the Evidence that a Dementia Treatment Works?.

Non–pharmacological Techniques.

Drugs in Development and Experimental Approaches.

SECTION V: Therapies for Cognitive Symptoms, Disease Modification and Prevention.

Introduction to Specific Therapies for Cognitive Symptoms or Modifying Disease Prognosis.

Treatment of Alzheimer′s Disease (With or Without Cerebrovascular disease).

Treatment of Vascular Dementia.

Treatment of Lewy Body Dementia.

Treatment of Reversible or Arrestable Dementias.

Treatment of Age–associated Memory Impairment.

Prevention of Dementia.

SECTION VI: Treating Non–cognitive Problems.

VI.A: A Problem–oriented Approach to Common Psychiatric Problems.


Classes of Psychotropics – Overview of Evidence from Clinical Trials.


Summary, Practical Recommendations and Opinions.

VI.B: A Problem–oriented Approach to Common Medical Problems.

Common Medical Problems.

SECTION VII: Social, Ethical and Health Services Issues.

Social and Ethical Issues.


Care–giver Interventions.

Genetic Counseling.

Nursing Home Care for Patients with Dementia.

Organisation of Care.

Memory Clinics – a Guide to Implementation and Evaluation.

Health Economics.

APPENDIX 1: Diagnostic Criteria for Common Dementias.

APPENDIX 2: Dementia Rating Scales.

APPENDIX 3: National Alzheimer′s Disease and Dementia Associations and Societies.

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Nawab Qizilbash
Lon S. Schneider
Henry Brodaty
Pierre Tariot
Jeffrey Kaye
Helena Chui
Timo Erkinjuntti
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