In these two volumes, each of the around 40 chapters covers one class of heterocycle, clearly structured as follows:
∗ Structural formulas of most important examples (market products)
∗ Short background of history or discovery
∗ Typical syntheses of important examples
∗ Mode of action
∗ Characteristic biological activity
∗ Structure–activity relationship
∗ Additional chemistry information
A valuable one–stop reference source for researchers in academia and industry as well as for graduate students with career aspirations in the field of pharmaceutical and agrochemical chemistry.
Penicillins and Cephalosporins
INFLAMMATION AND GASTROINTESTINAL DISEASES
Pyrimidine and Triazine Sulfonylureas
Pyridine and Thiazole Neonicotinoids
Pyrazole and Pyrimidine Acaricides
Jürgen Dinges obtained his M.S. degree in organic chemistry at the Technical University in Darmstadt, Germany, in 1988. He then joined the group of Prof. Frieder W. Lichtenthaler at the same university, where he received his Ph.D. degree in organic chemistry and chemical engineering in 1991. After being awarded a Feodor–Lynen scholarship from the Humboldt foundation, he spent 18 months as a postdoctoral fellow in the group of Prof. William G. Dauben at the University of California at Berkeley (USA). In 1993, Jürgen Dinges joined the department for biochemistry at Syntex, USA and since 1995 he is working in the pharmaceutical research department at Abbott Laboratories, USA. During his 18 years of industrial experience, Jürgen Dinges has specialized in drug discovery. In 2009, he was a guest editor for "Current Topics in Medicinal Chemistry" for a special issue on Parkinson′s disease. He is an author of 17 publications and 23 patents and a co–inventor of more than 10 clinical drug development candidates.