Severe Dementia

  • ID: 2325079
  • Book
  • 260 Pages
  • John Wiley and Sons Ltd
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Severe dementia is a relatively neglected area of psychiatry that attracts considerably less attention than the earlier stages of the illness. However, later stages of dementia are as important, if not more so, as the earlier stages, since they harbour unique characteristics and events which profoundly affect the lives of patients and their carers.

Severe Dementia addresses the special challenges faced by clinicians managing the late stage of this illness. After a brief introduction to diagnosis and the underlying pathology, a comprehensive section covers clinical features, such as behavioural disturbances and physical effects.  This is followed by the section on management, which addresses treatment options, both with drugs and non–pharmacologically, and health economics.  It also deals with ethical and nursing issues regarding caring for people in the terminal stages of illness, palliative care and the role of the family. 

Written and edited by an expert team of geriatric psychiatrists, Severe Dementia will be of value to all clinicians involved in the management of the complex and vulnerable group of patients.  It will also be of interest to general practitioners and carers in nursing homes.

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List of contributors.



Chapter 1: Assessment and Diagnosis of Severe Dementia (Paul Newhouse and Joseph Lasek).

Chapter 2: Neurochemistry of Severe Dementia (Sally I. Sharp, Paul T. Francis and Clive G. Ballard).

Chapter 3: The Molecular Pathology of Severe Dementia (Clive Holmes).


Chapter 4: Cognitive Functions in Severe Dementia (Judith Saxton and François Boller).

Chapter 5: Behavioural and Psychological Symptons of Dementia Agitation (E. Jane Byrne and Deborah Collins).

Chapter 6: Depression in Severe Dementia (Kate Bielinski and Brian Lawlor).

Chapter 7: Physical Aspects of Severe Alzheimer s Disease (Bruno Vellas).

Chapter 8: Clinical Features of Severe Dementia: Staging (Barry Reisberg, Jerzy Wegiel, Emile Franssen, Sridhar Kadiyala, Stefanie Auer, Liduïn Souren, Marwan Sabbagh and James Golomb).

Chapter 9: Clinical Features of Severe Dementia: Function (Serge Gauthier).


Chapter 10: Drug Treatment: Memantine (Anton P. Porsteinsson and Pierre N. Tariot).

Chapter 11: Drug Treatment: Cholinesterase Inhibitors (Michael Woodward and Howard Feldman).

Chapter 12: Drug Treatment: Treatment of Behavioural and Psychological Symptoms of Dementia with Neuroleptics (Peter Paul De Deyn).

Chapter 13: Non–pharmacological Treatment of Severe Dementia: An Overview (Ross Overshott and Alistair Burns).

Chapter 14: Non–pharmacological Treatment of Severe Dementia: the Seattle Protocols (Rebecca G. Logsdon, Linda Teri and Sue M. McCurry).

Chapter 15: Care by Families for Late Stage Dementia (Steven H. Zarit and Joseph E. Gaugler).

Chapter 16: Person–centred Care for People with Severe Dementia (Murna Downs, Neil Small and Katherine Froggatt).

Chapter 17: Palliative Care in Patients with Severe Dementia (Raymond Koopmans, H. Roeline W. Pasman and Jenny T. van der Steen).

Chapter 18: Narrative Ethics and Ethical Narratives in Dementia (Clive Baldwin).

Chapter 19: Health Economics of Severe Dementia (Anders Wimo and Bengt Winblad).


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Alistair Burns
Bengt Winblad
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