Therapeutics of Parkinson's Disease and Other Movement Disorders

  • ID: 2325433
  • Book
  • 512 Pages
  • John Wiley and Sons Ltd
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Over the past few decades, neurology has seen spectacular developments in diagnostic techniques, particularly in neuroimaging and molecular genetics, accompanied by an increasing number of effective therapies to treat neurological disease. This is particularly true for the field of movement disorders. Since the highly successful introduction of levodopa about 40 years ago, the therapeutic options for Parkinson's disease have grown exponentially, often making treatment decisions difficult.

This is the only current book on movement disorders to emphasize treatment. The authors, experts in their field, have used evidence from randomized controlled clinical trials to develop practical recommendations for every day clinical practice, bringing their personal clinical acumen and therapeutic wisdom to the book.

- Provides a comprehensive update on therapies for Parkinson's disease and other movement disorders
- Describes the basic mechanisms of neurodegeneration, pharmacologic interventions for motor and non–motor symptoms, and surgical management
- Features summary tables and algorithms that serve as a quick reference guide for practical treatment decisions
- The expert guidance of recognised authorities will enable readers of this book to plan their patients' care with greater confidence

Therapeutics of Parkinson's Disease & Other Movement Disorders is essential reading for residents in clinical neurology, clinical research fellows in neurology and related disciplines, general neurologists, and movement disorder specialists, as well as those working in the pharmaceutical industry with an interest in movement disorders.
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Preface.

Contributors.

PART I PARKINSON′S DISEASE AND PARKINSONISM.

1 The Etiopathogenesis of Parkinson′s Disease: Basic Mechanisms of Neurodegeneration (C. Warren Olanow and Kevin McNaught).

2 Physiology of Parkinson′s Disease (Shlomo Elias, Zvi Israel and Hagai Bergman).

3 Pharmacology of Parkinson′s Disease (Jonathan M. Brotchie).

4 The Treatment of Early Parkinson′s Disease (Olivier Rascol and Regina Katzenschlager).

5 Treatment of Motor Complications in Advanced Parkinson′s Disease (Susan H. Fox and Anthony E. Lang).

6 Managing the Non–Motor Symptoms of Parkinson′s Disease (Werner Poewe and Klaus Seppi).

7 Surgery for Parkinson′s Disease (Jens Volkmann).

8 Future Cell– and Gene–Based Therapies for Parkinson′s Disease (Tomas Bjorklund, Asuka Morizane, Deniz Kirik and Patrik Brundin).

9 Parkinson–Plus Disorders (Martin Kollensperger and Gregor K. Wenning).

PART II TREMOR DISORDERS.

10 Essential Tremor (Rodger J. Elble).

11 Other Tremor Disorders (Gunther Deuschl).

PART III DYSTONIA, CRAMPS, AND SPASMS.

12 Pathophysiology of Dystonia (Mark Hallett).

13 General Management Approach to Dystonia (Cynthia L. Comella).

14 Botulinum Toxin for Treatment of Dystonia (Dirk Dressler).

15 Surgical Treatments of Dystonia (Christopher Kenney and Joseph Jankovic).

16 Wilson′s Disease (George J. Brewer).

17 Cramps and Spasms (Christine D. Esper, Pratibha G. Aia, Leslie J. Cloud and Stewart A. Factor).

18 Stiff Person Syndrome (Philip D. Thompson and Hans–Michael Meinck).

PART IV CHOREA, TICS AND OTHER MOVEMENT DISORDERS.

19 Huntington′s Disease (Kevin M. Biglan and Ira Shoulson).

20 Chorea (Francisco Cardoso).

21 Treatment of Tics and Tourette Syndrome (Harvey S. Singer and Erika L.F. Hedderick).

22 Therapeutics of Paroxysmal Dyskinesias (Shyamal H. Mehta and Kapil D. Sethi).

23 Treatment of Miscellaneous Disorders (Marie Vidailhet, Emmanuel Roze and David Grabli).

24 Myoclonus (Shu–Ching Hu, Steven J. Frucht and Hiroshi Shibasaki).

PART V DRUG–INDUCED MOVEMENT DISORDERS.

25 Neuroleptic–Induced Movement Disorders (S. Elizabeth Zauber and Christopher G. Goetz).

26 Other Drug–Induced Dyskinesias (Oscar S. Gershanik).

PART VI ATAXIA AND DISORDERS OF GAIT AND BALANCE.

27 Ataxia (Thomas Klockgether).

28 Treatment of Gait and Balance Disorders (Bastiaan R. Bloem, Alexander C. Geurts, S. Hassin–Baer and Nir Giladi).

PART VII RESTLESS LEGS SYNDROME.

29 The Restless Legs Syndrome (Richard P. Allen and Birgit Hogl).

PART VIII PEDIATRIC MOVEMENT DISORDERS.

30 Pediatric Movement Disorders (Jonathan W. Mink).

PART IX PSYCHOGENIC MOVEMENT DISORDERS.

31 Psychogenic Movement Disorders (Elizabeth Peckham and Mark Hallett).

Index.

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"This book can be strongly recommended and is an asset to libraries of both movement disorder specialists and general neurologists. Its logical structure, linking therapy with underlying pathophysiology, means that it will remain a useful reference even as new therapies inevitably emerge." (The Lancet Neurology, July 2009)
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