With all the complex issues of acceptance or rejection of a transplanted organ, immunology is a key subject for all transplantation clinicians. During recent years, there has been an explosion of research and knowledge in this area.
Produced in association with the American Society of Transplantation, and written by experts within the field, Transplant Immunology provides a comprehensive overview of the topic in relation to clinical transplantation.
Starting with the basic functionality of the immune system, it then moves on to cover the very latest developments in immunosuppressive drugs and protocols, as well as a look at all emerging technologies in the field.
Key chapters include:
- Transplant–related complications
- Immune responses to transplants
- Emerging issues in transplantation
- Biomarkers of Allograft rejection and tolerance
- T cells and the principles of immune responses
In full colour throughout, over 100 outstanding diagrams support the text, all figures being fully downloadable via the book′s companion website. The result is an essential tool for all those responsible for managing patients awaiting and undergoing organ transplantation, including transplant surgeons and clinicians, immunologists and researchers.
About the companion website, xv
1 Tissues and organs of the immune system, 1Isam W. Nasr, Qiang Zeng, and Fadi G. Lakkis
2 Cells of the immune system, 25Jason R. Lees, Agnes M. Azimzadeh, Yaozhong Ding, Tonya J. Webb, and Jonathan S. Bromberg
3 Soluble mediators in the immune system, 48Charles A. Su, William M. Baldwin III, and Robert L. Fairchild
4 Costimulatory molecules, 65Maria ]Luisa Alegre and Anita S. Chong
5 Major histocompatibility complex, 85Raja Rajalingam, Qiuheng Zhang, J. Michael Cecka, and Elaine F. Reed
6 T cells and the principles of immune responses, 103Jonathan S. Maltzman, Angus Thomson, and David M. Rothstein
7 Ischemia and reperfusion injury, 128Yuan Zhai, Yoichiro Uchida, Bibo Ke, Haofeng Ji, and Jerzy W. Kupiec ]Weglinski
8 Immune responses to transplants, 142Denise J. Lo and Allan D. Kirk
9 Principles of hematopoietic cell transplantation, 164Sung Choi and Pavan Reddy
10 Therapeutic approaches to organ transplantation, 184Philip F. Halloran, Chatchai Kreepala, Gunilla Einecke, Alexandre Loupy, and Joana Sellarés
11 Organ ]specific features in clinical transplantation, 217Roslyn B. Mannon
12 Transplant ]related complications, 237Leonardo V. Riella and Anil Chandraker
13 Biomarkers of allograft rejection and tolerance, 259Choli Hartono, Thangamani Muthukumar, and Manikkam Suthanthiran
14 Emerging issues in transplantation, 280Rupert Oberhuber, Guangxiang Liu, Timm Heinbokel, and Stefan G. Tullius
15 New frontiers and new technologies, 297Haval Shirwan, Yiming Huang, Kadiyala Ravindra, and Suzanne T. Ildstad
16 Experimental models in discovery and translational studies, 316Andrew B. Adams, William H. Kitchens, and Kenneth A. Newell
Xian C. Li, MD, PhD, Professor of Immunology/surgery, Weill Cornell Medical College, Cornell University, New York, NY; and Director, Immunobiology and Transplant Science, Houston Methodist Hospital, Texas Medical Center, Houston, TX, USA.
Anthony M. Jevnikar MSc (Immunology), MD, FRCP(C), Professor of Medicine, Surgery, Immunology and Microbiology, Western University, Director Transplantation Nephrology and Director Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London ON, Canada.