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Profiles of Drug Substances, Excipients, and Related Methodology. Profiles of Drug Substances, Excipients and Related Methodology Volume 38

  • ID: 2485026
  • Book
  • August 2013
  • Elsevier Science and Technology

Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic.

The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

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- Alendronate Sodium

Gennady Ananchenko, Jasmina Novakovic, and Anna Tikhomirova

- Aripiprazole

Febry Ardiana, Maria L.A.D. Lestari, and Gunawan Indrayanto

- Butyl Methoxy Dibenzoylmethane

Jutta Kockler, Sherryl Robertson, Michael Oelgemöller, Murray Davies, Bruce Bowden, Harry G. Brittain, and Beverley D. Glass

- Carvedilol

Kevin Beattie, Geeta Phadke, and Jasmina Novakovic

- Melatonin

Fatmah A.M. Al-Omary

- Menadione

Ghada S. Hassan

- Analytical Profile of Moxidectin

Atul Awasthi, Majid Razzak, Raida Al-Kassas, Joanne Harvey, and Sanjay Garg

- Paroxetine Hydrochloride

David Germann, George Ma, Feixue Han, and Anna Tikhomirova

- Paroxetine Hydrochloride: Polymorphs and Solvatomorphs

Harry G. Brittain

- Sucralose

Omar A.A. AlDeeb, Hoda Mahgoub, and Nagwa H. Foda

- Tramadol Hydrochloride Robert Smyj, Xiao-Ping Wang, and Feixue Han
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Harry G. Brittain Center for Pharmaceutical Physics, Milford, NJ, USA.

Dr. Brittain is presently the Institute Director of the Center for Pharmaceutical Physics, a research and consulting institute he established in 1999 for the study of substances having pharmaceutical interest. His research interest include all areas of pharmaceutical physics and physical pharmacy, including preformulation, formulation design, product characterization, polymorphism, solvatomorphism, and cocrystals of drug substances. Formerly, Dr. Brittain was Vice President for Pharmaceutical Development of Discovery Laboratories, Inc., he served as Director of Pharmaceutical Development at Ohmeda, Inc., and also led a variety of groups within the Analytical R&D department at Bristol-Myers Squibb.

Dr. Brittain is a graduate of Queens College (B.A. in chemistry, 1970; M.A. in physical chemistry 1972), and of the City University of New York (Ph.D. in physical chemistry, 1975). He was a postdoctoral fellow at the University of Virginia, and has held full-time faculty positions at Ferrum College (Assistant Professor of Chemistry) and Seton Hall University (Associate Professor of Physical and Inorganic Chemistry). He has been Adjunct Professor of Pharmaceutics at Rutgers University, and both Adjunct Professor of Chemistry and Visiting Research Scientist at Lehigh University.

Dr. Brittain has authored over 340 research publications and book chapters, and has presented over 175 invited lectures and short courses in the pharmaceutical field. He has edited the monographs Analytical Applications of Circular Dichroism, Physical Characterization of Pharmaceutical Solids, Polymorphism in Pharmaceutical Solids (first and second editions), Spectroscopy of Pharmaceutical Solids, and Preformulation in Solid Dosage Form Development. He is also the Editor-In-Chief of the book series Profiles of Drug Substances, Excipients, and Related Methodology, having edited 23 published volumes in the series that is now published annually by Elsevier. Dr. Brittain is also an Editor of Physical Pharmacy for the Journal of Pharmaceutical Sciences, and is a co-author of 22 issued United States patents.

During his academic tenure at Seton Hall University, in 1980 Dr. Brittain was named as one of the Teacher-Scholars of the Camille and Henry Dreyfus Foundation. Dr. Brittain was elected as a Fellow of the American Association of Pharmaceutical Sciences (AAPS) in 1991, and received the AAPS Research Achievement Award in Analysis and Pharmaceutical Quality in 1998. He is also a Fellow of the Royal Society of Chemistry.
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