Functional Neural Transplantation III, Vol 200. Progress in Brain Research

  • ID: 2485250
  • Book
  • 448 Pages
  • Elsevier Science and Technology
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This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

- Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research- Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered- All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

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- Preface

Stephen Dunnett and Anders Björklund

- Transplantation in the Future

Fred H. Gage

- Ethical Challenges for Using Human Cells in Clinical Cell Therapy

Göran Hermerén

- Banking Stem Cells for Research and Clinical Applications

Glyn Stacey

- Survival, Differentiation and Connectivity of Ventral Mesencephalic Dopamine Neurons following Transplantation

Lachlan Thompson and Anders Björklund

- Electrophysiological Investigations of Synaptic Connectivity between Host and Graft Neurons

Jan Tønnesen and Merab Kokaia

- Nigral Grafts in Animal Models of Parkinson's Disease. Is Recovery beyond Motor Function Possible?

Mariah J. Lelos, Eilís Dowd and Stephen B. Dunnett

- L-DOPA- and Graft-Induced Dyskinesia following Transplantation

Emma L. Lane and Christian Winkler

- Current Status of Clinical Trials of Neural Transplantation in Parkinson's Disease

Jonathan R Evans, Sarah L Mason and Roger A Barker

- In vivo Imaging of the Integration and Function of Nigral Grafts in Clinical Trials

Marios Politis and Paola Piccini

- Neuropathology in Transplants in Parkinson's Disease: Implications for Disease Pathogenesis and the Future of Cell Therapy

Patrik Brundin and Jeffrey H. Kordower

- Derivation of Dopaminergic Neurons from Pluripotent Stem Cells

Lorenz Studer

- Characterization and Criteria of Embryonic Stem and Induced Pluripotent Stem Cells for a Dopamine Replacement Therapy

Oliver Cooper, Malin Parmar and Ole Isacson

- Skilled Motor Control for the Preclinical Assessment of Functional Deficits and Recovery following Nigral and Striatal Cell Transplantation

Alexander Klein and Ian Q. Whishaw

- Role of Experience, Training and Plasticity in the Functional Efficacy of Striatal Transplants

Máté D. Döbrössy and Guido Nikkhah

- In vivo Imaging of Integration and Function of Striatal Grafts in Rodent and Non-Human Primate Animal Models

Philippe Hantraye and Romina Aron Badin

- Clinical Trials of Neural Transplantation in Huntington's Disease

Anne E. Rosser and Anne-Catherine Bachoud-Lévi

- Derivation of Striatal Neurons from Human Stem Cells Pedro Viegas, Camille Nicoleau and Anselme L. Perrier
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